[Term]
id: PR:Q9Z1A5
name: NEDD8-activating enzyme E1 regulatory subunit (rat)
def: "A NEDD8-activating enzyme E1 regulatory subunit that is encoded in the genome of rat." [OMA:Q9Z1A5, PANTHER:PTHR10953:SF29, PRO:DNx]
comment: Category=organism-gene.
synonym: "Nae1" RELATED Gene-based [UniProtKB:Q9Z1A5]
synonym: "rNAE1" EXACT PRO-short-label [PRO:DNx]
synonym: "Appbp1" RELATED Gene-based [UniProtKB:Q9Z1A5]
synonym: "APP-BP1 (rat)" EXACT [UniProtKB:Q9Z1A5]
synonym: "amyloid protein-binding protein 1 (rat)" EXACT [UniProtKB:Q9Z1A5]
synonym: "amyloid beta precursor protein-binding protein 1, 59 kDa (rat)" EXACT [UniProtKB:Q9Z1A5]
xref: UniProtKB:Q9Z1A5
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000010957 ! NEDD8-activating enzyme E1 regulatory subunit
relationship: has_gene_template RGD:619945 ! Nae1 (rat)

[Term]
id: PR:Q9UT93
name: NEDD8-activating enzyme E1 regulatory subunit (Schizosaccharomyces pombe 972h-)
def: "A NEDD8-activating enzyme E1 regulatory subunit that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q9UT93, PANTHER:PTHR10953:SF29, PRO:DNx]
comment: Category=organism-gene.
synonym: "uba5" RELATED Gene-based [UniProtKB:Q9UT93]
synonym: "ula1" RELATED Gene-based [UniProtKB:Q9UT93]
synonym: "SPAC323.06c" RELATED Gene-based [UniProtKB:Q9UT93]
synonym: "Spom972h-NAE1" EXACT PRO-short-label [PRO:DNx]
synonym: "ubiquitin-like activation protein 1 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:Q9UT93]
synonym: "ubiquitin-activating enzyme E1-like 1 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:Q9UT93]
xref: UniProtKB:Q9UT93
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000010957 ! NEDD8-activating enzyme E1 regulatory subunit
relationship: has_gene_template PomBase:SPAC323.06c ! uba5 (Schizosaccharomyces pombe)

[Term]
id: PR:Q7SXP2-2
name: NEDD8-activating enzyme E1 regulatory subunit isoform 2 (zebrafish)
def: "A NEDD8-activating enzyme E1 regulatory subunit (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7SXP2-2." [PRO:DNx, UniProtKB:Q7SXP2]
comment: Category=organism-sequence.
synonym: "z-NAE1/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q7SXP2-2
is_a: PR:Q7SXP2 ! NEDD8-activating enzyme E1 regulatory subunit (zebrafish)
relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio

[Term]
id: PR:Q7SXP2-1
name: NEDD8-activating enzyme E1 regulatory subunit isoform 1 (zebrafish)
def: "A NEDD8-activating enzyme E1 regulatory subunit (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7SXP2-1." [PRO:DNx, UniProtKB:Q7SXP2]
comment: Category=organism-sequence.
synonym: "z-NAE1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q7SXP2-1
is_a: PR:Q7SXP2 ! NEDD8-activating enzyme E1 regulatory subunit (zebrafish)
relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio

[Term]
id: PR:Q5ZIE6
name: NEDD8-activating enzyme E1 regulatory subunit (chicken)
def: "A NEDD8-activating enzyme E1 regulatory subunit that is encoded in the genome of chicken." [OMA:Q5ZIE6, PANTHER:PTHR10953:SF29, PRO:DNx]
comment: Category=organism-gene.
synonym: "NAE1" RELATED Gene-based [UniProtKB:Q5ZIE6]
synonym: "APPBP1" RELATED Gene-based [UniProtKB:Q5ZIE6]
synonym: "chick-NAE1" EXACT PRO-short-label [PRO:DNx]
synonym: "RCJMB04_27g6" RELATED Gene-based [UniProtKB:Q5ZIE6]
synonym: "APP-BP1 (chicken)" EXACT [UniProtKB:Q5ZIE6]
synonym: "amyloid protein-binding protein 1 (chicken)" EXACT [UniProtKB:Q5ZIE6]
xref: UniProtKB:Q5ZIE6
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000010957 ! NEDD8-activating enzyme E1 regulatory subunit
relationship: has_gene_template NCBIGene:415792 ! NAE1 (chicken)

[Term]
id: PR:Q13564
name: NEDD8-activating enzyme E1 regulatory subunit (human)
def: "A NEDD8-activating enzyme E1 regulatory subunit that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13564]
comment: Category=organism-gene.
synonym: "HPP1" RELATED Gene-based [UniProtKB:Q13564]
synonym: "NAE1" RELATED Gene-based [UniProtKB:Q13564]
synonym: "hNAE1" EXACT PRO-short-label [PRO:DNx]
synonym: "APPBP1" RELATED Gene-based [UniProtKB:Q13564]
synonym: "APP-BP1 (human)" EXACT [UniProtKB:Q13564]
synonym: "proto-oncogene protein 1 (human)" EXACT [UniProtKB:Q13564]
synonym: "amyloid protein-binding protein 1 (human)" EXACT [UniProtKB:Q13564]
synonym: "amyloid beta precursor protein-binding protein 1, 59 kDa (human)" EXACT [UniProtKB:Q13564]
xref: UniProtKB:Q13564
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010957 ! NEDD8-activating enzyme E1 regulatory subunit
relationship: has_gene_template HGNC:621 ! NAE1 (human)

[Term]
id: PR:Q9VTE9
name: Nedd8-activating enzyme E1 regulatory subunit (fruit fly)
def: "A NEDD8-activating enzyme E1 regulatory subunit that is encoded in the genome of fruit fly." [OMA:Q9VTE9, PANTHER:PTHR10953:SF29, PRO:DNx]
comment: Category=organism-gene.
synonym: "CG7828" RELATED Gene-based [UniProtKB:Q9VTE9]
synonym: "APP-BP1" RELATED Gene-based [UniProtKB:Q9VTE9]
synonym: "dAPP-BP1" EXACT [UniProtKB:Q9VTE9]
synonym: "fly-NAE1" EXACT PRO-short-label [PRO:DNx]
synonym: "beta-amyloid precursor binding protein 1 (fruit fly)" EXACT [UniProtKB:Q9VTE9]
xref: UniProtKB:Q9VTE9
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000010957 ! NEDD8-activating enzyme E1 regulatory subunit
relationship: has_gene_template FlyBase:FBgn0261112 ! APP-BP1 (fruit fly)

[Term]
id: PR:Q8VBW6
name: NEDD8-activating enzyme E1 regulatory subunit (mouse)
def: "A NEDD8-activating enzyme E1 regulatory subunit that is encoded in the genome of mouse." [OMA:Q8VBW6, PRO:DNx]
comment: Category=organism-gene.
synonym: "Nae1" RELATED Gene-based [UniProtKB:Q8VBW6]
synonym: "mNAE1" EXACT PRO-short-label [PRO:DNx]
synonym: "Appbp1" RELATED Gene-based [UniProtKB:Q8VBW6]
synonym: "APP-BP1 (mouse)" EXACT [UniProtKB:Q8VBW6]
synonym: "amyloid protein-binding protein 1 (mouse)" EXACT [UniProtKB:Q8VBW6]
synonym: "amyloid beta precursor protein-binding protein 1, 59 kDa (mouse)" EXACT [UniProtKB:Q8VBW6]
xref: UniProtKB:Q8VBW6
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000010957 ! NEDD8-activating enzyme E1 regulatory subunit
relationship: has_gene_template MGI:2384561 ! Nae1 (mouse)

[Term]
id: PR:Q8VBW6-1
name: NEDD8-activating enzyme E1 regulatory subunit isoform 1 (mouse)
def: "A NEDD8-activating enzyme E1 regulatory subunit isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mNAE1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8VBW6-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040453 ! NEDD8-activating enzyme E1 regulatory subunit isoform 1

[Term]
id: PR:000010957
name: NEDD8-activating enzyme E1 regulatory subunit
def: "A protein that is a translation product of the human NAE1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "HPP1" RELATED Gene-based []
synonym: "NAE1" EXACT PRO-short-label [PRO:DNx]
synonym: "APPBP1" RELATED Gene-based []
synonym: "APP-BP1" EXACT []
synonym: "proto-oncogene protein 1" EXACT []
synonym: "amyloid protein-binding protein 1" EXACT []
synonym: "amyloid beta precursor protein-binding protein 1, 59 kDa" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q54JM3
name: NEDD8-activating enzyme E1 regulatory subunit (Dictyostelium discoideum)
def: "A NEDD8-activating enzyme E1 regulatory subunit that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54JM3, PANTHER:PTHR10953:SF29, PRO:DNx]
comment: Category=organism-gene.
synonym: "nae1" RELATED Gene-based [UniProtKB:Q54JM3]
synonym: "appbp1" RELATED Gene-based [UniProtKB:Q54JM3]
synonym: "Dicty-NAE1" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0287965" RELATED Gene-based [UniProtKB:Q54JM3]
xref: UniProtKB:Q54JM3
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000010957 ! NEDD8-activating enzyme E1 regulatory subunit
relationship: has_gene_template dictyBase:DDB_G0287965 ! nae1 (Dictyostelium discoideum)

[Term]
id: PR:000040453
name: NEDD8-activating enzyme E1 regulatory subunit isoform 1
def: "A NEDD8-activating enzyme E1 regulatory subunit that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13564-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "NAE1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010957 ! NEDD8-activating enzyme E1 regulatory subunit

[Term]
id: PR:Q9Z1A5-1
name: NEDD8-activating enzyme E1 regulatory subunit isoform 1 (rat)
def: "A NEDD8-activating enzyme E1 regulatory subunit isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rNAE1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Z1A5-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000040453 ! NEDD8-activating enzyme E1 regulatory subunit isoform 1

[Term]
id: PR:Q12059
name: NEDD8-activating enzyme E1 regulatory subunit (yeast)
def: "A NEDD8-activating enzyme E1 regulatory subunit that is encoded in the genome of yeast." [OMA:Q12059, PANTHER:PTHR10953:SF29, PRO:DNx]
comment: Category=organism-gene.
synonym: "ENR2" RELATED Gene-based [UniProtKB:Q12059]
synonym: "ULA1" RELATED Gene-based [UniProtKB:Q12059]
synonym: "yNAE1" EXACT PRO-short-label [PRO:DNx]
synonym: "LPA14W" RELATED Gene-based [UniProtKB:Q12059]
synonym: "YPL003W" RELATED Gene-based [UniProtKB:Q12059]
synonym: "E1 N-terminus-related protein 2 (yeast)" EXACT [UniProtKB:Q12059]
synonym: "ubiquitin-like activation protein 1 (yeast)" EXACT [UniProtKB:Q12059]
synonym: "ubiquitin-activating enzyme E1-like 1 (yeast)" EXACT [UniProtKB:Q12059]
xref: UniProtKB:Q12059
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000010957 ! NEDD8-activating enzyme E1 regulatory subunit
relationship: has_gene_template SGD:S000005924 ! ULA1 (yeast)

[Term]
id: PR:Q13564-4
name: NEDD8-activating enzyme E1 regulatory subunit isoform h4 (human)
def: "A NEDD8-activating enzyme E1 regulatory subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13564-4." [PRO:DNx, UniProtKB:Q13564]
comment: Category=organism-sequence.
synonym: "hNAE1/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13564-4
is_a: PR:Q13564 ! NEDD8-activating enzyme E1 regulatory subunit (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q18217
name: NEDD8-activating enzyme E1 regulatory subunit (worm)
def: "A NEDD8-activating enzyme E1 regulatory subunit that is encoded in the genome of worm." [OMA:Q18217, PANTHER:PTHR10953:SF29, PRO:DNx]
comment: Category=organism-gene.
synonym: "ula-1" RELATED Gene-based [UniProtKB:Q18217]
synonym: "C26E6.8" RELATED Gene-based [UniProtKB:Q18217]
synonym: "NAE1 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "ubiquitin-like activation protein 1 (worm)" EXACT [UniProtKB:Q18217]
xref: UniProtKB:Q18217
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000010957 ! NEDD8-activating enzyme E1 regulatory subunit
relationship: has_gene_template WormBase:WBGene00006735 ! ula-1 (worm)

[Term]
id: PR:Q7SXP2
name: NEDD8-activating enzyme E1 regulatory subunit (zebrafish)
def: "A NEDD8-activating enzyme E1 regulatory subunit that is encoded in the genome of zebrafish." [OMA:Q7SXP2, PANTHER:PTHR10953:SF29, PRO:DNx]
comment: Category=organism-gene.
synonym: "nae1" RELATED Gene-based [UniProtKB:Q7SXP2]
synonym: "appbp1" RELATED Gene-based [UniProtKB:Q7SXP2]
synonym: "z-NAE1" EXACT PRO-short-label [PRO:DNx]
synonym: "APP-BP1 (zebrafish)" EXACT [UniProtKB:Q7SXP2]
synonym: "amyloid protein-binding protein 1 (zebrafish)" EXACT [UniProtKB:Q7SXP2]
xref: UniProtKB:Q7SXP2
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000010957 ! NEDD8-activating enzyme E1 regulatory subunit
relationship: has_gene_template ZFIN:ZDB-GENE-040426-1552 ! nae1 (zebrafish)

[Term]
id: PR:Q13564-1
name: NEDD8-activating enzyme E1 regulatory subunit isoform 1 (human)
def: "A NEDD8-activating enzyme E1 regulatory subunit isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hNAE1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13564-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040453 ! NEDD8-activating enzyme E1 regulatory subunit isoform 1

[Term]
id: PR:Q13564-2
name: NEDD8-activating enzyme E1 regulatory subunit isoform h2 (human)
def: "A NEDD8-activating enzyme E1 regulatory subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13564-2." [PRO:DNx, UniProtKB:Q13564]
comment: Category=organism-sequence.
synonym: "hNAE1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13564-2
is_a: PR:Q13564 ! NEDD8-activating enzyme E1 regulatory subunit (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13564-3
name: NEDD8-activating enzyme E1 regulatory subunit isoform h3 (human)
def: "A NEDD8-activating enzyme E1 regulatory subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13564-3." [PRO:DNx, UniProtKB:Q13564]
comment: Category=organism-sequence.
synonym: "hNAE1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13564-3
is_a: PR:Q13564 ! NEDD8-activating enzyme E1 regulatory subunit (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens