[Term]
id: PR:P10085
name: myoblast determination protein 1 (mouse)
def: "A myoblast determination protein 1 that is encoded in the genome of mouse." [OMA:P10085, PRO:DNx]
comment: Category=organism-gene.
synonym: "Myod" RELATED Gene-based [UniProtKB:P10085]
synonym: "Myod1" RELATED Gene-based [UniProtKB:P10085]
synonym: "mMYOD1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10085
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000010875 ! myoblast determination protein 1
relationship: has_gene_template MGI:97275 ! Myod1 (mouse)

[Term]
id: PR:P16075
name: myoblast determination protein 1 homolog (chicken)
def: "A myoblast determination protein 1 that is encoded in the genome of chicken." [OMA:P16075, PANTHER:PTHR11534:SF2, PRO:DNx]
comment: Category=organism-gene.
synonym: "CMD1" RELATED Gene-based [UniProtKB:P16075]
synonym: "MYOD" RELATED Gene-based [UniProtKB:P16075]
synonym: "MYOD1" RELATED Gene-based [UniProtKB:P16075]
synonym: "chick-MYOD1" EXACT PRO-short-label [PRO:DNx]
synonym: "MYOD1 homolog (chicken)" EXACT [UniProtKB:P16075]
xref: UniProtKB:P16075
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000010875 ! myoblast determination protein 1
relationship: has_gene_template NCBIGene:374048 ! MYOD1 (chicken)

[Term]
id: PR:000029168
name: myoblast determination protein 1 phosphorylated 3 (mouse)
def: "A myoblast determination protein 1 phosphorylated 3 in mouse. This phosphorylation decreases DNA binding activity. UniProtKB:P10085, Thr-115, MOD:00047." [PMID:17761773, PRO:ALI]
comment: Category=organism-modification.
synonym: "mMYOD1/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "murine myod1 pT115" RELATED []
synonym: "myod phosphorylated (mouse)" RELATED []
synonym: "myod1 phosphorylated (mouse)" RELATED []
synonym: "UniProtKB:P10085, Thr-115, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000029167 ! myoblast determination protein 1 phosphorylated 3
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000029166
name: myoblast determination protein 1 phosphorylated 2 (mouse)
def: "A myoblast determination protein 1 phosphorylated 2 in mouse. This phosphorylation occurs via activation of the cyclin B-Cdc2 complex, and represseses transcriptional activity of the protein. UniProtKB:P10085, Ser-5/Ser-200, MOD:00046." [PMID:14749395, PRO:ALI]
comment: Category=organism-modification. Kinase=("Cyclin B-Cdc2 complex").
synonym: "mMYOD1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "murine myod1 pS5/pS200" RELATED []
synonym: "myod phosphorylated (mouse)" RELATED []
synonym: "myod1 phosphorylated (mouse)" RELATED []
synonym: "UniProtKB:P10085, Ser-5/Ser-200, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000029165 ! myoblast determination protein 1 phosphorylated 2
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000029167
name: myoblast determination protein 1 phosphorylated 3
def: "A myoblast determination protein 1 that has been phosphorylated on a Thr residue within the DNA-binding domain. Example: UniProtKB:P10085, Thr-115, MOD:00047." [PMID:17761773, PRO:ALI]
comment: Category=modification.
synonym: "myod1 pT115" RELATED []
synonym: "MYOD1/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "myod phosphorylated" RELATED []
synonym: "myod1 phosphorylated" RELATED []
is_a: PR:000010875 ! myoblast determination protein 1
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000029164
name: myoblast determination protein 1 unmodified form (mouse)
def: "A myoblast determination protein 1 unmodified form in mouse." [PRO:CNA]
comment: Category=organism-modification.
synonym: "mMYOD1/UnMod" EXACT PRO-short-label [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000029163 ! myoblast determination protein 1 unmodified form

[Term]
id: PR:000029165
name: myoblast determination protein 1 phosphorylated 2
def: "A myoblast determination protein 1 that has been phosphorylated on in a Ser located in the transactivation domain, and the second Ser residue of the consecutive Ser residues in the motif GDSDASSPRSNC. These Ser are in consensus CDK sites ([ST]P). Example: UniProtKB:P10085, Ser-5/Ser-200, MOD:00046." [PMID:14749395, PRO:ALI]
comment: Category=modification.
synonym: "MYOD1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "myod1 pS5/pS200" RELATED []
synonym: "myod phosphorylated" RELATED []
synonym: "myod1 phosphorylated" RELATED []
is_a: PR:000010875 ! myoblast determination protein 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000029162
name: myoblast determination protein 1 phosphorylated 1 (mouse)
def: "A myoblast determination protein 1 phosphorylated 1 in mouse. This phosphorylated form shows decreased transcription factor activity towards myogenin. UniProtKB:P10085, Ser-199/Ser-200, MOD:00046." [PMID:20026657, PRO:ALI]
comment: Category=organism-modification. Kinase=("MAPK12"; PR:O08911).
synonym: "mMYOD1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "myod phosphorylated (mouse)" RELATED []
synonym: "myod1 phosphorylated (mouse)" RELATED []
synonym: "UniProtKB:P10085, Ser-199/Ser-200, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000029161 ! myoblast determination protein 1 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000029163
name: myoblast determination protein 1 unmodified form
def: "A myoblast determination protein 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "MYOD1/UnMod" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000010875 ! myoblast determination protein 1
intersection_of: has_part PR:000021935 ! immature protein part
intersection_of: lacks_part PR:000025513 ! modified amino-acid residue
disjoint_from: PR:000018264 ! proteolytic cleavage product

[Term]
id: PR:000029161
name: myoblast determination protein 1 phosphorylated 1
def: "A myoblast determination protein 1 that has been phosphorylated on either one or two of the consecutive Ser residues in the motif GDSDASSPRSNC. This phosphorylation occurs via activation of the MAPK12 (p38 gamma) dependent signaling. Example: UniProtKB:P10085, Ser-199/Ser-200, MOD:00046." [PMID:20026657, PRO:ALI]
comment: Category=modification.
synonym: "MYOD1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "myod phosphorylated" RELATED []
synonym: "myod1 phosphorylated" RELATED []
is_a: PR:000010875 ! myoblast determination protein 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:P10085-1
name: myoblast determination protein 1 isoform 1 (mouse)
def: "A myoblast determination protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:PD]
comment: Category=organism-sequence.
synonym: "mMYOD1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10085-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000028759 ! myoblast determination protein 1 isoform 1

[Term]
id: PR:000010875
name: myoblast determination protein 1
def: "A protein that is a translation product of the human MYOD1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MYF3" RELATED Gene-based []
synonym: "MYOD" RELATED Gene-based []
synonym: "MYOD1" EXACT PRO-short-label [PRO:DNx]
synonym: "Myf-3" EXACT []
synonym: "BHLHC1" RELATED Gene-based []
synonym: "bHLHc1" EXACT []
synonym: "myogenic factor 3" EXACT []
synonym: "class C basic helix-loop-helix protein 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P15172
name: myoblast determination protein 1 (human)
def: "A myoblast determination protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P15172]
comment: Category=organism-gene.
synonym: "MYF3" RELATED Gene-based [UniProtKB:P15172]
synonym: "MYOD" RELATED Gene-based [UniProtKB:P15172]
synonym: "MYOD1" RELATED Gene-based [UniProtKB:P15172]
synonym: "BHLHC1" RELATED Gene-based [UniProtKB:P15172]
synonym: "hMYOD1" EXACT PRO-short-label [PRO:DNx]
synonym: "Myf-3 (human)" EXACT [UniProtKB:P15172]
synonym: "myogenic factor 3 (human)" EXACT [UniProtKB:P15172]
synonym: "class C basic helix-loop-helix protein 1 (human)" EXACT [UniProtKB:P15172]
xref: Reactome:R-HSA-445441 "PR:P15172 located_in GO:0005654"
xref: UniProtKB:P15172
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010875 ! myoblast determination protein 1
relationship: has_gene_template HGNC:7611 ! MYOD1 (human)

[Term]
id: PR:Q90477
name: myoblast determination protein 1 homolog (zebrafish)
def: "A myoblast determination protein 1 that is encoded in the genome of zebrafish." [OMA:Q90477, PANTHER:PTHR11534:SF2, PRO:DNx]
comment: Category=organism-gene.
synonym: "myod" RELATED Gene-based [UniProtKB:Q90477]
synonym: "myod1" RELATED Gene-based [UniProtKB:Q90477]
synonym: "z-MYOD1" EXACT PRO-short-label [PRO:DNx]
synonym: "myogenic factor 1 (zebrafish)" EXACT [UniProtKB:Q90477]
xref: UniProtKB:Q90477
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000010875 ! myoblast determination protein 1
relationship: has_gene_template ZFIN:ZDB-GENE-980526-561 ! myod1 (zebrafish)

[Term]
id: PR:Q02346
name: myoblast determination protein 1 (rat)
def: "A myoblast determination protein 1 that is encoded in the genome of rat." [PANTHER:PTHR11534:SF2, PRO:DNx]
comment: Category=organism-gene.
synonym: "Myod" RELATED Gene-based [UniProtKB:Q02346]
synonym: "Myod1" RELATED Gene-based [UniProtKB:Q02346]
synonym: "rMYOD1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q02346
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000010875 ! myoblast determination protein 1
relationship: has_gene_template RGD:631429 ! Myod1 (rat)

[Term]
id: PR:P15172-1
name: myoblast determination protein 1 isoform 1 (human)
def: "A myoblast determination protein 1 isoform 1 that is encoded in the genome of human." [PRO:PD]
comment: Category=organism-sequence.
synonym: "hMYOD1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P15172-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000028759 ! myoblast determination protein 1 isoform 1

[Term]
id: PR:000045682
name: myoblast determination protein 1 phosphorylated 1 (human)
def: "A myoblast determination protein 1 (human) that has been phosphorylated at Ser-200. UniProtKB:P15172, Ser-200, MOD:00046." [PMID:9710583, iPTMnet:P15172]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:9710583). Status=unreviewed.
synonym: "hMYOD1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P15172, Ser-200, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P15172 ! myoblast determination protein 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000028762
name: myoblast determination protein 1 isoform 1 acetylated 1 (human)
def: "A myoblast determination protein 1 isoform 1 acetylated 1 in human. Acetylation increases the transactivating capability of the protein. UniProtKB:P15172-1, Lys-99/Lys-102, MOD:00064." [PMID:10944526, PRO:PD]
comment: Category=organism-modification. Acetylase=("CREBBP/EP300"; PR:000027108).
synonym: "hMYOD1/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P15172-1, Lys-99/Lys-102, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000028761 ! myoblast determination protein 1 isoform 1 acetylated 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:000028761
name: myoblast determination protein 1 isoform 1 acetylated 1
def: "A myoblast determination protein 1 isoform 1 that has been acetylated on Lys residues located at the boundary of the DNA binding/dimerization domain. Example: UniProtKB:P15172-1, Lys-99/Lys-102, MOD:00064." [PMID:10944526, PRO:PD]
comment: Category=modification.
synonym: "MYOD1/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000028759 ! myoblast determination protein 1 isoform 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:000028759
name: myoblast determination protein 1 isoform 1
def: "A myoblast determination protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15172-1 or a 1:1 ortholog thereof." [PMID:10944526, PRO:PD]
comment: Category=sequence.
synonym: "MYOD1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010875 ! myoblast determination protein 1