[Term]
id: PR:000045425
name: microtubule-associated protein tau sequence variant A152T (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Thr residue at the position equivalent to Ala-152 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; Ala-469 in PNS-Tau). Example: UniProtKB:P10636-8, Ala-152, CHEBI:30013." [Alzforum:KD, PMID:21176711, PMID:22556362, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:A152T" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Ala-152, CHEBI:30013" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-a152t
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045427
name: microtubule-associated protein tau sequence variant G200E (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Glu residue at the position equivalent to Gly-200 of the amino acid sequence represented by UniProtKB:P10636-1 (PNS-Tau; residue encoded within an exon missing from Tau-F). Example: UniProtKB:P10636-1, Gly-200, CHEBI:29972." [Alzforum:KD, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:G200E" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-1, Gly-200, CHEBI:29972" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-g200e
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045426
name: microtubule-associated protein tau sequence variant A178T (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Thr residue at the position equivalent to Ala-178 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; Ala-495 in PNS-Tau). Example: UniProtKB:P10636-8, Ala-178, CHEBI:30013." [Alzforum:KD, PMID:10443890, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:A178T" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Ala-178, CHEBI:30013" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-a178t
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000028709
name: microtubule-associated protein tau sequence variant R5H (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a His residue at the position equivalent to Arg-5 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; same residue in PNS-Tau). Example: UniProtKB:P10636-8, Arg-5, CHEBI:29979." [Alzforum:KD, PMID:11921059, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:R5H" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Arg-5, CHEBI:29979" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_019660
xref: Alzforum_mut:mapt-r5h
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000028708
name: microtubule-associated protein tau sequence variant (human)
def: "A microtubule-associated protein tau (human) that has at least one amino acid residue that differs from the corresponding residue found in another microtubule-associated protein tau (human) when such a difference arises as the result of genetic differences, i.e., different alleles of microtubule-associated protein tau (human). Operationally, this means the sequence representation of the microtubule-associated protein tau (human) has at least one amino acid residue that differs from the corresponding residue found in the amino acid sequence represented by UniProtKB:P10636-1." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:P10636 ! microtubule-associated protein tau (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000027678
name: microtubule-associated protein tau isoform Tau-C phosphorylated 7 (human)
def: "A microtubule-associated protein tau isoform Tau-C phosphorylated 7 in human. UniProtKB:P10636-5, Ser-199/Ser-202/Ser-262/Ser-365/Ser-373, MOD:00046|Thr-205, MOD:00047." [PMID:9485060, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "Tau 69" BROAD [PRO:DNx]
synonym: "3R-Tau 69" EXACT []
synonym: "hMAPT/iso:Tau-C/Phos:7" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-5, Ser-199/Ser-202/Ser-262/Ser-365/Ser-373, MOD:00046|Thr-205, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027677 ! microtubule-associated protein tau isoform Tau-C phosphorylated 7
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000027670
name: microtubule-associated protein tau isoform Tau-F phosphorylated 15 (human)
def: "A microtubule-associated protein tau isoform Tau-F phosphorylated 15 in human. UniProtKB:P10636-8, Ser-356, MOD:00046." [PMID:20658989, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-F/Phos:15" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-356, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027669 ! microtubule-associated protein tau isoform Tau-F phosphorylated 15
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000027672
name: microtubule-associated protein tau isoform Tau-F phosphorylated 18 (human)
def: "A microtubule-associated protein tau isoform Tau-F phosphorylated 18 in human. UniProtKB:P10636-8, Ser-199/Ser-202/Ser-214, MOD:00046|Thr-205/Thr-212, MOD:00047." [PMID:10090668, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-F/Phos:18" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-199/Ser-202/Ser-214, MOD:00046|Thr-205/Thr-212, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027671 ! microtubule-associated protein tau isoform Tau-F phosphorylated 18
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000027674
name: microtubule-associated protein tau isoform Tau-E phosphorylated 7 (human)
def: "A microtubule-associated protein tau isoform Tau-E phosphorylated 7 in human. UniProtKB:P10636-7, Ser-170/Ser-173/Ser-233/Ser-367/Ser-375, MOD:00046|Thr-176, MOD:00047." [PMID:9485060, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "Tau 69" BROAD [PRO:DNx]
synonym: "4R-Tau 69" EXACT []
synonym: "hMAPT/iso:Tau-E/Phos:7" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-7, Ser-170/Ser-173/Ser-233/Ser-367/Ser-375, MOD:00046|Thr-176, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027673 ! microtubule-associated protein tau isoform Tau-E phosphorylated 7
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000027676
name: microtubule-associated protein tau isoform Tau-D phosphorylated 7 (human)
def: "A microtubule-associated protein tau isoform Tau-D phosphorylated 7 in human. UniProtKB:P10636-6, Ser-140/Ser-144/Ser-204/Ser-338/Ser-346, MOD:00046|Thr-147, MOD:00047." [PMID:9485060, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "Tau 64" BROAD [PRO:DNx]
synonym: "4R-Tau 64" EXACT []
synonym: "hMAPT/iso:Tau-D/Phos:7" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-6, Ser-140/Ser-144/Ser-204/Ser-338/Ser-346, MOD:00046|Thr-147, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027675 ! microtubule-associated protein tau isoform Tau-D phosphorylated 7
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000037549
name: microtubule-associated protein tau sequence variant V363I (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Ile residue at the position equivalent to Val-363 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Val-680 in PNS-Tau). Example: UniProtKB:P10636-8, Val-363, CHEBI:30009." [Alzforum:KD, PMID:17712160, PMID:21343707, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:V363I" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Val-363, CHEBI:30009" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-v363i
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037548
name: microtubule-associated protein tau sequence variant S352L (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Leu residue at the position equivalent to Ser-352 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Ser-669 in PNS-Tau). Example: UniProtKB:P10636-8, Ser-352, CHEBI:30006." [Alzforum:KD, PMID:14595660, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_019667 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:S352L" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Ser-352, CHEBI:30006" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_019667
xref: Alzforum_mut:mapt-s352l
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037543
name: microtubule-associated protein tau sequence variant S320F (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Phe residue at the position equivalent to Ser-320 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Ser-637 in PNS-Tau). Example: UniProtKB:P10636-8, Ser-320, CHEBI:29997." [Alzforum:KD, PMID:11891833, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_019665 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:S320F" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Ser-320, CHEBI:29997" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_019665
xref: Alzforum_mut:mapt-s320f
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037542
name: microtubule-associated protein tau sequence variant S320Y (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Tyr residue at the position equivalent to Ser-320 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Ser-637 in PNS-Tau). Example: UniProtKB:P10636-8, Ser-320, CHEBI:46858." [Alzforum:KD, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:S320Y" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Ser-320, CHEBI:46858" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-s320y
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037541
name: microtubule-associated protein tau sequence variant K317M (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Met residue at the position equivalent to Lys-317 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Lys-634 in PNS-Tau). Example: UniProtKB:P10636-8, Lys-317, CHEBI:16044." [Alzforum:KD, PMID:15883319, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_037440 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:K317M" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Lys-317, CHEBI:16044" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_037440
xref: Alzforum_mut:mapt-k317m
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037540
name: microtubule-associated protein tau sequence variant L315R (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Arg residue at the position equivalent to Leu-315 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Arg-632 in PNS-Tau)). Example: UniProtKB:P10636-8, Leu-315, CHEBI:29952." [Alzforum:KD, PMID:14595646, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:L315R" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Leu-315, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-l315r
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037547
name: microtubule-associated protein tau sequence variant E342V (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Val residue at the position equivalent to Glu-342 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Glu-659 in PNS-Tau). Example: UniProtKB:P10636-8, Glu-342, CHEBI:30015." [Alzforum:KD, PMID:11117541, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_019666 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:E342V" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Glu-342, CHEBI:30015" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_019666
xref: Alzforum_mut:mapt-e342v
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037546
name: microtubule-associated protein tau sequence variant V337M (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Met residue at the position equivalent to Val-337 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Val-654 in PNS-Tau). Example: UniProtKB:P10636-8, Val-337, CHEBI:16044." [Alzforum:KD, PMID:1734292, PMID:9629852, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_010351 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:V337M" EXACT PRO-short-label [PRO:DAN]
synonym: "Seattle Family A MAPT" EXACT [Alzforum_mut:mapt-v337m-seattle-family]
synonym: "UniProtKB:P10636-8, Val-337, CHEBI:16044" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_010351
xref: Alzforum_mut:mapt-v337m-seattle-family
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037545
name: microtubule-associated protein tau sequence variant Q336R (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Arg residue at the position equivalent to Gln-336 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Gln-653 in PNS-Tau). Example: UniProtKB:P10636-8, Gln-336, CHEBI:29952." [Alzforum:KD, PMID:15047590, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:Q336R" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Gln-336, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-q336r
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037544
name: microtubule-associated protein tau sequence variant G335S (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Ser residue at the position equivalent to Gly-335 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka GLy-652 in PNS-Tau). Example: UniProtKB:P10636-8, Gly-335, CHEBI:29999." [Alzforum:KD, PMID:17186252, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:G335S" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Gly-335, CHEBI:29999" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-g335s
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000050508
name: microtubule-associated protein tau unphosphorylated 9 (human)
def: "A microtubule-associated protein tau (human) that has not been phosphorylated at the position equivalent to Ser-396 of the amino acid sequence represented by UniProtKB:P10636-8. Example: UniProtKB:P10636-8, Ser-396, PR:000026291." [PRO:DAN]
comment: Category=organism-modification.
synonym: "hMAPT/UnPhos:9" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636, Ser-713, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-1, Ser-713, PR:000026291" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-396, PR:000026291" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P10636 ! microtubule-associated protein tau (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037528
name: microtubule-associated protein tau sequence variant G272V (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Val residue at the position equivalent to Gly-272 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Gly-589 in PNS-Tau). Example: UniProtKB:P10636-8, Gly-272, CHEBI:30015." [Alzforum:KD, PMID:9641683, PMID:9811325, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_010345 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:G272V" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Gly-272, CHEBI:30015" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_010345
xref: Alzforum_mut:mapt-g272v
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000027668
name: microtubule-associated protein tau isoform Tau-F phosphorylated 14 (human)
def: "A microtubule-associated protein tau isoform Tau-F phosphorylated form (human) that has been phosphorylated at the first threonine and the third Ser in the motif AVVRTPPKSPSS. UniProtKB:P10636-8, Thr-231, MOD:00047|Ser-238, MOD:00046." [PMID:16443603, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-F/Phos:14" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Thr-231, MOD:00047|Ser-238, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:000027446 ! microtubule-associated protein tau isoform Tau-F phosphorylated form (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000010173
name: microtubule-associated protein tau
def: "A protein that is a translation product of the human MAPT gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene. Requested by=Alzforum.
synonym: "TAU" RELATED Gene-based []
synonym: "MAPT" EXACT PRO-short-label [PRO:DNx]
synonym: "MAPTL" RELATED Gene-based []
synonym: "MTBT1" RELATED Gene-based []
synonym: "Mtapt" RELATED Gene-based []
synonym: "PHF-tau" EXACT []
synonym: "paired helical filament-tau" EXACT []
synonym: "neurofibrillary tangle protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000027662
name: microtubule-associated protein tau isoform Tau-F phosphorylated 10 (human)
def: "A microtubule-associated protein tau isoform Tau-F phosphorylated 10 in human. UniProtKB:P10636-8, Thr-217, MOD:00047." [PMID:16443603, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-F/Phos:10" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Thr-217, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027661 ! microtubule-associated protein tau isoform Tau-F phosphorylated 10
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000027660
name: microtubule-associated protein tau isoform Tau-F phosphorylated 9 (human)
def: "A microtubule-associated protein tau isoform Tau-F phosphorylated 9 in human. UniProtKB:P10636-8, Ser-396, MOD:00046." [PMID:16443603, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-F/Phos:9" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-396, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027659 ! microtubule-associated protein tau isoform Tau-F phosphorylated 9
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000027667
name: microtubule-associated protein tau isoform Tau-F phosphorylated 13 (human)
def: "A microtubule-associated protein tau isoform Tau-F phosphorylated form (human) that has been phosphorylated at the first threonine and the first Ser in the motif AVVRTPPKSPSS. UniProtKB:P10636-8, Thr-231, MOD:00047|Ser-235, MOD:00046." [PMID:16443603, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-F/Phos:13" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Thr-231, MOD:00047|Ser-235, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:000027446 ! microtubule-associated protein tau isoform Tau-F phosphorylated form (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037526
name: microtubule-associated protein tau sequence variant I260V (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Val residue at the position equivalent to Ile-260 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Ile-577 in PNS-Tau). Example: UniProtKB:P10636-8, Ile-260, CHEBI:30015." [Alzforum:KD, PMID:14637086, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:I260V" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Ile-260, CHEBI:30015" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-i260v
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000027664
name: microtubule-associated protein tau isoform Tau-F phosphorylated 11 (human)
def: "A microtubule-associated protein tau isoform Tau-F phosphorylated 11 in human. UniProtKB:P10636-8, Ser-214, MOD:00046|Thr-217, MOD:00047." [PMID:16443603, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-F/Phos:11" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-214, MOD:00046|Thr-217, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027663 ! microtubule-associated protein tau isoform Tau-F phosphorylated 11
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000045406
name: microtubule-associated protein tau sequence variant A90V (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Val residue at the position equivalent to Ala-90 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; same residue in PNS-Tau). Example: UniProtKB:P10636-8, Ala-90, CHEBI:30015." [Alzforum:KD, PMID:25937274, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:A90V" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ala-90, CHEBI:30015" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-a90v
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045405
name: microtubule-associated protein tau sequence variant A41T (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Thr residue at the position equivalent to Ala-41 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; same residue in PNS-Tau). Example: UniProtKB:P10636-8, Ala-41, CHEBI:30013." [Alzforum:KD, PMID:25604855, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:A41T" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ala-41, CHEBI:30013" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-a41t
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045404
name: microtubule-associated protein tau sequence variant P4T (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Thr residue at the position equivalent to Pro-4 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; same residue in PNS-Tau). Example: UniProtKB:P10636-8, Pro-4, CHEBI:30013." [Alzforum:KD, PMID:25937274, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:P4T" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Pro-4, CHEBI:30013" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-p4t
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045403
name: microtubule-associated protein tau sequence variant R5C (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Cys residue at the position equivalent to Arg-5 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; same residue in PNS-Tau). Example: UniProtKB:P10636-8, Arg-5, CHEBI:29950." [Alzforum:KD, PMID:25604855, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:R5C" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Arg-5, CHEBI:29950" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-r5c
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000027656
name: microtubule-associated protein tau isoform Tau-F phosphorylated 7 (human)
def: "A microtubule-associated protein tau isoform Tau-F phosphorylated 7 in human. UniProtKB:P10636-8, Ser-199/Ser-202/Ser-262/Ser-396/Ser-404, MOD:00046|Thr-205, MOD:00047." [PMID:9485060, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "Tau 74" EXACT []
synonym: "hMAPT/iso:Tau-F/Phos:7" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-199/Ser-202/Ser-262/Ser-396/Ser-404, MOD:00046|Thr-205, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027655 ! microtubule-associated protein tau isoform Tau-F phosphorylated 7
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:P10636-4
name: microtubule-associated protein tau isoform Tau-B (human)
def: "A microtubule-associated protein tau isoform Tau-B that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10636-4
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026995 ! microtubule-associated protein tau isoform Tau-B

[Term]
id: PR:000027658
name: microtubule-associated protein tau isoform Tau-F phosphorylated 8 (human)
def: "A microtubule-associated protein tau isoform Tau-F phosphorylated 8 in human. UniProtKB:P10636-8, Ser-262, MOD:00046." [PMID:16443603, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-F/Phos:8" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-262, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027657 ! microtubule-associated protein tau isoform Tau-F phosphorylated 8
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:P10636
name: microtubule-associated protein tau (human)
def: "A microtubule-associated protein tau that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-gene. Requested by=Alzforum.
synonym: "TAU" RELATED Gene-based [UniProtKB:P10636]
synonym: "MAPT" RELATED Gene-based [UniProtKB:P10636]
synonym: "MAPTL" RELATED Gene-based [UniProtKB:P10636]
synonym: "MTBT1" RELATED Gene-based [UniProtKB:P10636]
synonym: "hMAPT" EXACT PRO-short-label [PRO:DNx]
synonym: "PHF-tau (human)" EXACT [UniProtKB:P10636]
synonym: "paired helical filament-tau (human)" EXACT [UniProtKB:P10636]
synonym: "neurofibrillary tangle protein (human)" EXACT [UniProtKB:P10636]
xref: UniProtKB:P10636
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000010173 ! microtubule-associated protein tau
relationship: has_gene_template HGNC:6893 ! MAPT (human)

[Term]
id: PR:P10636-7
name: microtubule-associated protein tau isoform Tau-E (human)
def: "A microtubule-associated protein tau isoform Tau-E that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-E" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10636-7
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026998 ! microtubule-associated protein tau isoform Tau-E

[Term]
id: PR:000044550
name: microtubule-associated protein tau sequence variant P512H (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a His residue at the position equivalent to Pro-512 of the amino acid sequence represented by UniProtKB:P10636-9 (Tau-G; residue encoded within an exon missing from Tau-F and PNS-Tau). Example: UniProtKB:P10636-9, Pro-512, CHEBI:29979." [Alzforum:KD, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:P512H" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-9, Pro-512, CHEBI:29979" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-p512h
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045666
name: microtubule-associated protein tau phosphorylated 1 (human)
def: "A microtubule-associated protein tau (human) that has been phosphorylated at the position equivalent to Tyr-18 of the amino acid sequence represented by UniProtKB:P10636-1. Example: UniProtKB:P10636-1, Tyr-18, MOD:00048." [PMID:18070606, iPTMnet:P10636]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:18070606). Status=unreviewed.
synonym: "hMAPT/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-1, Tyr-18, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P10636 ! microtubule-associated protein tau (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045438
name: microtubule-associated protein tau sequence variant S318L (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Leu residue at the position equivalent to Ser-318 of the amino acid sequence represented by UniProtKB:P10636-1 (PNS-Tau; residue encoded within an exon missing from Tau-F). Example: UniProtKB:P10636-1, Ser-318, CHEBI:30006." [Alzforum:KD, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:S318L" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-1, Ser-318, CHEBI:30006" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-s318l
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045439
name: microtubule-associated protein tau sequence variant P332S (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Ser residue at the position equivalent to Pro-332 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; Pro-649 in PNS-Tau). Example: UniProtKB:P10636-8, Pro-332, CHEBI:29999." [Alzforum:KD, PMID:22699846, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:P332S" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Pro-332, CHEBI:29999" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-p332s
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000036993
name: microtubule-associated protein tau sequence variant Q336H (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a His residue at the position equivalent to Gln-336 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; Gln-653 in PNS-Tau). Example: UniProtKB:P10636-8, Gln-336, CHEBI:29979." [Alzforum:KD, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:Q336H" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Gln-336, CHEBI:29979" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-q336h
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000036992
name: microtubule-associated protein tau sequence variant G335V (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Val residue at the position equivalent to Gly-335 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; Gly-652 in PNS-Tau). Example: UniProtKB:P10636-8, Gly-335, CHEBI:30015." [Alzforum:KD, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:G335V" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Gly-335, CHEBI:30015" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-g335v
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045432
name: microtubule-associated protein tau sequence variant S285R (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Arg residue at the position equivalent to Ser-285 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; Ser-602 in PNS-Tau). Example: UniProtKB:P10636-8, Ser-285, CHEBI:29952." [Alzforum:KD, PMID:22818528, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:S285R" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Ser-285, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-s285r
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045433
name: microtubule-associated protein tau sequence variant V287I (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Ile residue at the position equivalent to Val-287 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; Val-604 in PNS-Tau). Example: UniProtKB:P10636-8, Val-287, CHEBI:30009." [Alzforum:KD, PMID:22906081, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:V287I" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Val-287, CHEBI:30009" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-v287i
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045430
name: microtubule-associated protein tau sequence variant V224G (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Gly residue at the position equivalent to Val-224 of the amino acid sequence represented by UniProtKB:P10636-1 (PNS-Tau; residue encoded within an exon missing from Tau-F). Example: UniProtKB:P10636-1, Val-224, CHEBI:29947." [Alzforum:KD, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:V224G" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-1, Val-224, CHEBI:29947" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-v224g
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045431
name: microtubule-associated protein tau sequence variant A239T (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Thr residue at the position equivalent to Ala-239 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; Ala-556 in PNS-Tau). Example: UniProtKB:P10636-8, Ala-239, CHEBI:30013." [Alzforum:KD, PMID:11912108, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:A239T" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Ala-239, CHEBI:30013" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-a239t
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045436
name: microtubule-associated protein tau sequence variant A297V (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Val residue at the position equivalent to Ala-297 of the amino acid sequence represented by UniProtKB:P10636-1 (PNS-Tau; residue encoded within an exon missing from Tau-F). Example: UniProtKB:P10636-1, Ala-297, CHEBI:30015." [Alzforum:KD, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:A297V" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-1, Ala-297, CHEBI:30015" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-a297v
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045437
name: microtubule-associated protein tau sequence variant K317N (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Asn residue at the position equivalent to Lys-317 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; Lys-634 in PNS-Tau). Example: UniProtKB:P10636-8, Lys-317, CHEBI:50347." [Alzforum:KD, PMID:25900293, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:K317N" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Lys-317, CHEBI:50347" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-k317n
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045434
name: microtubule-associated protein tau sequence variant C291R (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Arg residue at the position equivalent to Cys-291 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; Cys-608 in PNS-Tau). Example: UniProtKB:P10636-8, Cys-291, CHEBI:29952." [Alzforum:KD, PMID:26402116, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:C291R" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Cys-291, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-c291r
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045435
name: microtubule-associated protein tau sequence variant N296D (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Asp residue at the position equivalent to Asn-296 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; Asn-613 in PNS-Tau). Example: UniProtKB:P10636-8, Asn-296, CHEBI:29958." [Alzforum:KD, PMID:25108559, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:N296D" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Asn-296, CHEBI:29958" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-n296d
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000027640
name: microtubule-associated protein tau phosphorylated 11 (human)
def: "A microtubule-associated protein tau phosphorylated 11 in human. Example: UniProtKB:P10636-8, Ser-214, MOD:00046|Thr-217, MOD:00047." [PMID:16443603, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/Phos:11" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636, Ser-531, MOD:00046|Thr-534, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-1, Ser-531, MOD:00046|Thr-534, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-214, MOD:00046|Thr-217, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027639 ! microtubule-associated protein tau phosphorylated 11
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000027642
name: microtubule-associated protein tau phosphorylated 12 (human)
def: "A microtubule-associated protein tau phosphorylated 12 in human. Example: UniProtKB:P10636-8, Thr-231, MOD:00047." [PMID:16443603, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/Phos:12" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636, Thr-548, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-1, Thr-548, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-8, Thr-231, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027641 ! microtubule-associated protein tau phosphorylated 12
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000027645
name: microtubule-associated protein tau phosphorylated 16 (human)
def: "A microtubule-associated protein tau phosphorylated 16 in human. Example: UniProtKB:P10636-8, Ser-202, MOD:00046|Thr-205, MOD:00047." [PMID:19413330, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/Phos:16" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636, Ser-519, MOD:00046|Thr-522, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-202, MOD:00046|Thr-205, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027644 ! microtubule-associated protein tau phosphorylated 16
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000027647
name: microtubule-associated protein tau phosphorylated 17 (human)
def: "A microtubule-associated protein tau phosphorylated 17 in human. Example: UniProtKB:P10636-8, Ser-202, MOD:00046." [PMID:19413330, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/Phos:17" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636, Ser-519, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-1, Ser-519, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-202, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027646 ! microtubule-associated protein tau phosphorylated 17
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000027649
name: microtubule-associated protein tau phosphorylated 18 (human)
def: "A microtubule-associated protein tau phosphorylated 18 in human. Example: UniProtKB:P10636-8, Ser-199/Ser-202/Ser-214, MOD:00046|Thr-205/Thr-212, MOD:00047." [PMID:10090668, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/Phos:18" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636, Ser-516/Ser-519/Ser-531, MOD:00046|Thr-522/Thr-529, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-1, Ser-516/Ser-519/Ser-531, MOD:00046|Thr-522/Thr-529, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-199/Ser-202/Ser-214, MOD:00046|Thr-205/Thr-212, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027648 ! microtubule-associated protein tau phosphorylated 18
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000044549
name: microtubule-associated protein tau sequence variant L410F (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Phe residue at the position equivalent to Leu-410 of the amino acid sequence represented by UniProtKB:P10636-1 (PNS-Tau; residue encoded within an exon missing from Tau-F). Example: UniProtKB:P10636-1, Leu-410, CHEBI:29997." [Alzforum:KD, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:L410F" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-1, Leu-410, CHEBI:29997" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-l410f
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000044548
name: microtubule-associated protein tau sequence variant Q230R (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Arg residue at the position equivalent to Gln-230 of the amino acid sequence represented by UniProtKB:P10636-1 (PNS-Tau; residue encoded within an exon missing from Tau-F). Example: UniProtKB:P10636-1, Gln-230, CHEBI:29952." [Alzforum:KD, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:Q230R" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-1, Gln-230, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-q230r
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000027430
name: microtubule-associated protein tau isoform Tau-F phosphorylated 3 (human)
def: "A microtubule-associated protein tau isoform Tau-F phosphorylated 3 in human. UniProtKB:P10636-8, Tyr-197, MOD:00048|Ser-198, MOD:00046." [PMID:16923168, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-F/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Tyr-197, MOD:00048|Ser-198, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027429 ! microtubule-associated protein tau isoform Tau-F phosphorylated 3
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:000037532
name: microtubule-associated protein tau sequence variant L284R (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Arg residue at the position equivalent to Leu-284 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Leu-601 in PNS-Tau). Example: UniProtKB:P10636-8, Leu-284, CHEBI:29952." [Alzforum:KD, PMID:20838030, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:L284R" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Leu-284, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-l284r
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037533
name: microtubule-associated protein tau sequence variant N296H (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a His residue at the position equivalent to Asn-296 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Asn-613 in PNS-Tau). Example: UniProtKB:P10636-8, Asn-296, CHEBI:29979." [Alzforum:KD, PMID:11585254, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_019663 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:N296H" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Asn-296, CHEBI:29979" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_019663
xref: Alzforum_mut:mapt-n296h
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037530
name: microtubule-associated protein tau sequence variant N279K (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Lys residue at the position equivalent to Asn-279 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Asn-596 in PNS-Tau). Example: UniProtKB:P10636-8, Asn-279, CHEBI:29967." [Alzforum:KD, PMID:1416801, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_010346 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:N279K" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Asn-279, CHEBI:29967" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_010346
xref: Alzforum_mut:mapt-n279k
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037531
name: microtubule-associated protein tau sequence variant K280del (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a single-residue deletion at the position equivalent to Lys-280 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Lys-597 in PNS-Tau). Example: UniProtKB:P10636-8, 1-279, 281-441." [Alzforum:KD, PMID:17723255, PMID:9973279, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_010347 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:K280del" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-1, 1-596, 598-758" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "UniProtKB:P10636-8, 1-279, 281-441" NARROW PRO-proteoform-std [PRO:DAN]
xref: UniProtKB_VAR:VAR_010347
xref: Alzforum_mut:mapt-k280del
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037536
name: microtubule-associated protein tau sequence variant P301L (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Leu residue at the position equivalent to Pro-301 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Pro-618 in PNS-Tau). Example: UniProtKB:P10636-8, Pro-301, CHEBI:30006." [Alzforum:KD, PMID:9641683, PMID:9736786, PMID:9789048, PMID:9811325, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_010348 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:P301L" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Pro-301, CHEBI:30006" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_010348
xref: Alzforum_mut:mapt-p301l
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037537
name: microtubule-associated protein tau sequence variant G303V (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Val residue at the position equivalent to Gly-303 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka GLy-620 in PNS-Tau). Example: UniProtKB:P10636-8, Gly-303, CHEBI:30015." [Alzforum:KD, PMID:16157753, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_037439 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:G303V" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Gly-303, CHEBI:30015" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_037439
xref: Alzforum_mut:mapt-g303v
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037534
name: microtubule-associated protein tau sequence variant P301S (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Ser residue at the position equivalent to Pro-301 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Pro-618 in PNS-Tau). Example: UniProtKB:P10636-8, Pro-301, CHEBI:29999." [Alzforum:KD, PMID:10374757, PMID:10553987, PMID:12796837, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_010349 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:P301S" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Pro-301, CHEBI:29999" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_010349
xref: Alzforum_mut:mapt-p301s
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037535
name: microtubule-associated protein tau sequence variant P301T (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Thr residue at the position equivalent to Pro-301 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Pro-618 in PNS-Tau). Example: UniProtKB:P10636-8, Pro-301, CHEBI:30013." [Alzforum:KD, PMID:17662000, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:P301T" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Pro-301, CHEBI:30013" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-p301t
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037538
name: microtubule-associated protein tau sequence variant S305I (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Ile residue at the position equivalent to Ser-305 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Ser-622 in PNS-Tau). Example: UniProtKB:P10636-8, Ser-305, CHEBI:30009." [Alzforum:KD, PMID:18066559, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:S305I" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Ser-305, CHEBI:30009" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-s305i
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037539
name: microtubule-associated protein tau sequence variant S305N (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Asn residue at the position equivalent to Ser-305 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Ser-622 in PNS-Tau). Example: UniProtKB:P10636-8, Ser-305, CHEBI:50347." [Alzforum:KD, PMID:10208578, PMID:12143928, PMID:12928922, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_010350 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:S305N" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Ser-305, CHEBI:50347" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_010350
xref: Alzforum_mut:mapt-s305n
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045429
name: microtubule-associated protein tau sequence variant G213R (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Arg residue at the position equivalent to Gly-213 of the amino acid sequence represented by UniProtKB:P10636-1 (PNS-Tau; residue encoded within an exon missing from Tau-F). Example: UniProtKB:P10636-1, Gly-213, CHEBI:29952." [Alzforum:KD, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:G213R" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-1, Gly-213, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-g213r
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045428
name: microtubule-associated protein tau sequence variant R211H (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a His residue at the position equivalent to Arg-211 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; Arg-528 in PNS-Tau). Example: UniProtKB:P10636-8, Arg-211, CHEBI:29979." [Alzforum:KD, PMID:25604855, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:R211H" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Arg-211, CHEBI:29979" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-r211h
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045446
name: microtubule-associated protein tau sequence variant P511R (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Arg residue at the position equivalent to Pro-511 of the amino acid sequence represented by UniProtKB:P10636-9 (Tau-G; residue encoded within an exon missing from Tau-F and PNS-Tau). Example: UniProtKB:P10636-9, Pro-511, CHEBI:29952." [Alzforum:KD, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:P511R" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-9, Pro-511, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-p511r
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045444
name: microtubule-associated protein tau sequence variant S427F (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Phe residue at the position equivalent to Ser-427 of the amino acid sequence represented by UniProtKB:P10636-1 (PNS-Tau; residue encoded within an exon missing from Tau-F). Example: UniProtKB:P10636-1, Ser-427, CHEBI:29997." [Alzforum:KD, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:S427F" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-1, Ser-427, CHEBI:29997" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-s427f
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000027635
name: microtubule-associated protein tau phosphorylated 9 (human)
def: "A microtubule-associated protein tau phosphorylated 9 in human. Example: UniProtKB:P10636-8, Ser-396, MOD:00046." [PMID:16443603, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/Phos:9" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636, Ser-713, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-1, Ser-713, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-396, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027634 ! microtubule-associated protein tau phosphorylated 9
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000027631
name: microtubule-associated protein tau phosphorylated 7 (human)
def: "A microtubule-associated protein tau phosphorylated 7 in human. Example: UniProtKB:P10636-8, Ser-199/Ser-202/Ser-262/Ser-396/Ser-404, MOD:00046|Thr-205, MOD:00047." [PMID:9485060, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "Tau 55" NARROW [PRO:DAN]
synonym: "Tau 69" NARROW [PRO:DAN]
synonym: "Tau 74" NARROW [PRO:DAN]
synonym: "hMAPT/Phos:7" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636, Ser-516/Ser-519/Ser-579/Ser-713/Ser-721, MOD:00046|Thr-522, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-1, Ser-516/Ser-519/Ser-579/Ser-713/Ser-721, MOD:00046|Thr-522, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-199/Ser-202/Ser-262/Ser-396/Ser-404, MOD:00046|Thr-205, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027630 ! microtubule-associated protein tau phosphorylated 7
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000027633
name: microtubule-associated protein tau phosphorylated 8 (human)
def: "A microtubule-associated protein tau phosphorylated 8 in human. Example: UniProtKB:P10636-8, Ser-262, MOD:00046." [PMID:16443603, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/Phos:8" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636, Ser-579, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-1, Ser-579, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-262, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027632 ! microtubule-associated protein tau phosphorylated 8
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000027638
name: microtubule-associated protein tau phosphorylated 10 (human)
def: "A microtubule-associated protein tau phosphorylated 10 in human. Example: UniProtKB:P10636-8, Thr-217, MOD:00047." [PMID:16443603, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/Phos:10" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636, Thr-534, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-1, Thr-534, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P10636-8, Thr-217, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027637 ! microtubule-associated protein tau phosphorylated 10
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000027450
name: microtubule-associated protein tau isoform Tau-F phosphorylated 2 (human)
def: "A microtubule-associated protein tau isoform Tau-F phosphorylated 2 in human. UniProtKB:P10636-8, Thr-231, MOD:00047." [PMID:16443603, PRO:CG, PRO:DAN]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-F/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "hMAPT/iso:Tau-F/Phos:12" EXACT [PRO:CG]
synonym: "UniProtKB:P10636-8, Thr-231, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "microtubule-associated protein tau isoform Tau-F phosphorylated 12 (human)" EXACT [PRO:CG]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027449 ! microtubule-associated protein tau isoform Tau-F phosphorylated 2
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:P10636-5
name: microtubule-associated protein tau isoform Tau-C (human)
def: "A microtubule-associated protein tau isoform Tau-C that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-C" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10636-5
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026996 ! microtubule-associated protein tau isoform Tau-C

[Term]
id: PR:P10636-6
name: microtubule-associated protein tau isoform Tau-D (human)
def: "A microtubule-associated protein tau isoform Tau-D that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-D" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10636-6
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026997 ! microtubule-associated protein tau isoform Tau-D

[Term]
id: PR:000027453
name: microtubule-associated protein tau isoform Tau-F phosphorylated 4 (human)
def: "A microtubule-associated protein tau isoform Tau-F phosphorylated 4 in human. UniProtKB:P10636-8, Ser-199/Ser-202, MOD:00046." [PMID:16923168, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-F/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-199/Ser-202, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027452 ! microtubule-associated protein tau isoform Tau-F phosphorylated 4
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:P10636-1
name: microtubule-associated protein tau isoform PNS-tau (human)
def: "A microtubule-associated protein tau isoform PNS-tau that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/iso:PNS-tau" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10636-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026992 ! microtubule-associated protein tau isoform PNS-tau

[Term]
id: PR:000027456
name: microtubule-associated protein tau isoform Tau-F phosphorylated 5 (human)
def: "A microtubule-associated protein tau isoform Tau-F phosphorylated 5 in human. UniProtKB:P10636-8, Ser-422, MOD:00046|Thr-427, MOD:00047." [PMID:16923168, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-F/Phos:5" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-422, MOD:00046|Thr-427, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027455 ! microtubule-associated protein tau isoform Tau-F phosphorylated 5
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:P10636-3
name: microtubule-associated protein tau isoform Tau-A (human)
def: "A microtubule-associated protein tau isoform Tau-A that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10636-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026994 ! microtubule-associated protein tau isoform Tau-A

[Term]
id: PR:000027459
name: microtubule-associated protein tau isoform Tau-F phosphorylated 6 (human)
def: "A microtubule-associated protein tau isoform Tau-F phosphorylated 6 in human. UniProtKB:P10636-8, Ser-416/Ser-422, MOD:00046|Thr-427, MOD:00047." [PMID:16923168, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-F/Phos:6" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Ser-416/Ser-422, MOD:00046|Thr-427, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027458 ! microtubule-associated protein tau isoform Tau-F phosphorylated 6
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:P10636-8
name: microtubule-associated protein tau isoform Tau-F (human)
def: "A microtubule-associated protein tau isoform Tau-F that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hTau40" EXACT []
synonym: "hMAPT/iso:Tau-F" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10636-8
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026999 ! microtubule-associated protein tau isoform Tau-F

[Term]
id: PR:P10636-9
name: microtubule-associated protein tau isoform Tau-G (human)
def: "A microtubule-associated protein tau (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10636-9." [PRO:DNx, UniProtKB:P10636]
comment: Category=organism-sequence.
synonym: "hMAPT/iso:Tau-G" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10636-9
is_a: PR:P10636 ! microtubule-associated protein tau (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048335
name: microtubule-associated protein tau, initiator methionine removed form (human)
def: "A microtubule-associated protein tau (human) that has had the initiator methionine removed. UniProtKB:P10636, 2-758." [PRO:DNx, Reactome:R-HSA-201574]
comment: Category=organism-modification.
synonym: "PRO_0000072739" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hMAPT/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636, 2-758" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-201574 "PR:000048335 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P10636 ! microtubule-associated protein tau (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045443
name: microtubule-associated protein tau sequence variant G366R (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Arg residue at the position equivalent to Gly-366 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; GLy-683 in PNS-Tau). Example: UniProtKB:P10636-8, Gly-366, CHEBI:29952." [Alzforum:KD, PMID:21943955, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:G366R" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Gly-366, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-g366r
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045442
name: microtubule-associated protein tau sequence variant P364S (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Ser residue at the position equivalent to Pro-364 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; Pro-681 in PNS-Tau). Example: UniProtKB:P10636-8, Pro-364, CHEBI:29999." [Alzforum:KD, PMID:21943955, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:P364S" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Pro-364, CHEBI:29999" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-p364s
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045441
name: microtubule-associated protein tau sequence variant I360V (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Val residue at the position equivalent to Ile-360 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; Ile-677 in PNS-Tau). Example: UniProtKB:P10636-8, Ile-360, CHEBI:30015." [Alzforum:KD, PMID:25604855, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:I360V" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Ile-360, CHEBI:30015" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-i360v
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045440
name: microtubule-associated protein tau sequence variant S356T (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Thr residue at the position equivalent to Ser-356 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; Ser-673 in PNS-Tau). Example: UniProtKB:P10636-8, Ser-356, CHEBI:30013." [Alzforum:KD, PMID:20708332, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:S356T" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Ser-356, CHEBI:30013" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-s356t
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000027680
name: microtubule-associated protein tau isoform Tau-B phosphorylated 7 (human)
def: "A microtubule-associated protein tau isoform Tau-B phosphorylated 7 in human. UniProtKB:P10636-4, Ser-170/Ser-173/Ser-233/Ser-336/Ser-344, MOD:00046|Thr-176, MOD:00047." [PMID:9485060, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "Tau 64" BROAD [PRO:DNx]
synonym: "3R-Tau 64" EXACT []
synonym: "hMAPT/iso:Tau-B/Phos:7" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-4, Ser-170/Ser-173/Ser-233/Ser-336/Ser-344, MOD:00046|Thr-176, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027679 ! microtubule-associated protein tau isoform Tau-B phosphorylated 7
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000045445
name: microtubule-associated protein tau sequence variant R448* (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a premature stop at the position equivalent to Arg-448 of the amino acid sequence represented by UniProtKB:P10636-1 (PNS-Tau; residue encoded within an exon missing from Tau-F). Example: UniProtKB:P10636-1, 1-447." [Alzforum:KD, PMID:21943955, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:R448*" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-1, 1-447" NARROW PRO-proteoform-std [PRO:DAN]
xref: Alzforum_mut:mapt-r448
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000027682
name: microtubule-associated protein tau isoform Fetal-tau phosphorylated 7 (human)
def: "A microtubule-associated protein tau isoform Fetal-tau phosphorylated 7 in human. UniProtKB:P10636-2, Ser-141/Ser-144/Ser-204/Ser-307/Ser-315, MOD:00046|Thr-147, MOD:00047." [PMID:9485060, PRO:CG]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "Tau 55" EXACT []
synonym: "hMAPT/iso:Fetal-tau/Phos:7" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-2, Ser-141/Ser-144/Ser-204/Ser-307/Ser-315, MOD:00046|Thr-147, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027681 ! microtubule-associated protein tau isoform Fetal-tau phosphorylated 7
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000028725
name: microtubule-associated protein tau sequence variant V300I (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Ile residue at the position equivalent to Val-300 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Val-617 in PNS-Tau). Example: UniProtKB:P10636-8, Val-300, CHEBI:30009." [Alzforum:KD, PMID:20020531, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_064624 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:V300I" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Val-300, CHEBI:30009" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_064624
xref: Alzforum_mut:mapt-v300i
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000028724
name: microtubule-associated protein tau sequence variant N296del (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a single-residue deletion at the position equivalent to Asn-296 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Asn-613 in PNS-Tau). Example: UniProtKB:P10636-8, 1-295, 297-441." [Alzforum:KD, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_019664 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:N296del" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-1, 1-612, 614-758" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "UniProtKB:P10636-8, 1-295, 297-441" NARROW PRO-proteoform-std [PRO:DAN]
xref: UniProtKB_VAR:VAR_019664
xref: Alzforum_mut:mapt-n296del-dn296
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037529
name: microtubule-associated protein tau sequence variant G273R (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Arg residue at the position equivalent to Gly-273 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Gly-590 in PNS-Tau). Example: UniProtKB:P10636-8, Gly-273, CHEBI:29952." [Alzforum:KD, PMID:16495329, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:G273R" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Gly-273, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-g273r
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000027446
name: microtubule-associated protein tau isoform Tau-F phosphorylated form (human)
def: "A microtubule-associated protein tau isoform Tau-F phosphorylated form in human." [PRO:DAN]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "pTau" BROAD [PRO:DNx]
synonym: "hMAPT/iso:Tau-F/PhosRes+" EXACT PRO-short-label [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027445 ! microtubule-associated protein tau isoform Tau-F phosphorylated form

[Term]
id: PR:000037525
name: microtubule-associated protein tau sequence variant K257T (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Thr residue at the position equivalent to Lys-257 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Lys-574 in PNS-Tau). Example: UniProtKB:P10636-8, Lys-257, CHEBI:30013." [Alzforum:KD, PMID:11089577, PMID:11117542, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_010344 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:K257T" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Lys-257, CHEBI:30013" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_010344
xref: Alzforum_mut:mapt-k257t
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037524
name: microtubule-associated protein tau sequence variant P202L (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Leu residue at the position equivalent to Pro-202 of the amino acid sequence represented by UniProtKB:P10636-1 (PNS-Tau; residue encoded within an exon missing from Tau-F). Example: UniProtKB:P10636-1, Pro-202, CHEBI:30006." [Alzforum:KD, PMID:10643890, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:P202L" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-1, Pro-202, CHEBI:30006" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-p202l
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037527
name: microtubule-associated protein tau sequence variant L266V (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Val residue at the position equivalent to Leu-266 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Leu-583 in PNS-Tau). Example: UniProtKB:P10636-8, Leu-266, CHEBI:30015." [Alzforum:KD, PMID:12509859, PMID:12883828, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_019662 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:L266V" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Leu-266, CHEBI:30015" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_019662
xref: Alzforum_mut:mapt-l266v
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000027448
name: microtubule-associated protein tau isoform Tau-F phosphorylated 1 (human)
def: "A microtubule-associated protein tau isoform Tau-F phosphorylated 1 in human. UniProtKB:P10636-8, Thr-181, MOD:00047." [PRO:DAN]
comment: Category=organism-modification. Requested by=Alzforum.
synonym: "hMAPT/iso:Tau-F/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Thr-181, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027447 ! microtubule-associated protein tau isoform Tau-F phosphorylated 1
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000037521
name: microtubule-associated protein tau sequence variant G55R (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Arg residue at the position equivalent to Gly-55 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; same residue in PNS-Tau). Example: UniProtKB:P10636-8, Gly-55, CHEBI:29952." [Alzforum:KD, PMID:24086739, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:G55R" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Gly-55, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-g55r
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037523
name: microtubule-associated protein tau sequence variant G86S (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Ser residue at the position equivalent to Gly-86 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; same residue in PNS-Tau). Example: UniProtKB:P10636-8, Gly-86, CHEBI:29999." [Alzforum:KD, PMID:15372253, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:G86S" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Gly-86, CHEBI:29999" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-g86s
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037522
name: microtubule-associated protein tau sequence variant V75A (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Ala residue at the position equivalent to Val-75 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; same residue in PNS-Tau). Example: UniProtKB:P10636-8, Val-75, CHEBI:46217." [Alzforum:KD, PMID:19768372, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:V75A" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Val-75, CHEBI:46217" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-v75a
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P10636-2
name: microtubule-associated protein tau isoform Fetal-tau (human)
def: "A microtubule-associated protein tau isoform Fetal-tau that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/iso:Fetal-tau" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10636-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026993 ! microtubule-associated protein tau isoform Fetal-tau

[Term]
id: PR:000028712
name: microtubule-associated protein tau sequence variant T30A (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Ala residue at the position equivalent to Thr-30 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; same residue in PNS-Tau). Example: UniProtKB:P10636-8, Thr-30, CHEBI:46217." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:T30A" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Thr-30, CHEBI:46217" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_064623
xref: Alzforum_mut:mapt-t30a
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000028713
name: microtubule-associated protein tau sequence variant D285N (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Asn residue at the position equivalent to Asp-285 of the amino acid sequence represented by UniProtKB:P10636-1 (PNS-Tau; residue encoded within an exon missing from Tau-F). Example: UniProtKB:P10636-1, Asp-285, CHEBI:50347." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:D285N" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-1, Asp-285, CHEBI:50347" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_010340
xref: Alzforum_mut:mapt-d285n
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000028710
name: microtubule-associated protein tau sequence variant R5L (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Lys residue at the position equivalent to Arg-5 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; same residue in PNS-Tau). Example: UniProtKB:P10636-8, Arg-5, CHEBI:29967." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:R5L" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Arg-5, CHEBI:29967" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_019661
xref: Alzforum_mut:mapt-r5l
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000028711
name: microtubule-associated protein tau sequence variant T17M (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Met residue at the position equivalent to Thr-17 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; same residue in PNS-Tau). Example: UniProtKB:P10636-8, Thr-17, CHEBI:16044." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:T17M" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-8, Thr-17, CHEBI:16044" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_064622
xref: Alzforum_mut:mapt-t17m
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000028716
name: microtubule-associated protein tau sequence variant Y441H (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a His residue at the position equivalent to Tyr-441 of the amino acid sequence represented by UniProtKB:P10636-1 (PNS-Tau; residue encoded within an exon missing from Tau-F). Example: UniProtKB:P10636-1, Tyr-441, CHEBI:29979." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: Both alleles Y441 and H441 occur in healthy individuals. Hence Alzforum describes both in a single entry.
synonym: "hMAPT/var:H441Y" EXACT [Alzforum_mut:mapt-h441y]
synonym: "hMAPT/var:Y441H" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-1, Tyr-441, CHEBI:29979" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_010342
xref: Alzforum_mut:mapt-h441y
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000028717
name: microtubule-associated protein tau sequence variant S447P (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Pro residue at the position equivalent to Ser-447 of the amino acid sequence represented by UniProtKB:P10636-1 (PNS-Tau; residue encoded within an exon missing from Tau-F). Example: UniProtKB:P10636-1, Ser-447, CHEBI:50342." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:S447P" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-1, Ser-447, CHEBI:50342" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_010343
xref: Alzforum_mut:mapt-s447p
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000028714
name: microtubule-associated protein tau sequence variant V289A (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Ala residue at the position equivalent to Val-289 of the amino acid sequence represented by UniProtKB:P10636-1 (PNS-Tau; residue encoded within an exon missing from Tau-F). Example: UniProtKB:P10636-1, Val-289, CHEBI:46217." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:V289A" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-1, Val-289, CHEBI:46217" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_010341
xref: Alzforum_mut:mapt-v289a
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000028715
name: microtubule-associated protein tau sequence variant R370W (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Trp residue at the position equivalent to Arg-370 of the amino acid sequence represented by UniProtKB:P10636-1 (PNS-Tau; residue encoded within an exon missing from Tau-F). Example: UniProtKB:P10636-1, Arg-370, CHEBI:29954." [PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:R370W" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10636-1, Arg-370, CHEBI:29954" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_056121
xref: Alzforum_mut:mapt-r370w
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037550
name: microtubule-associated protein tau sequence variant K369I (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Ile residue at the position equivalent to Lys-369 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Lys-686 in PNS-Tau). Example: UniProtKB:P10636-8, Lys-369, CHEBI:30009." [Alzforum:KD, PMID:11601501, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_019668 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:K369I" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Lys-369, CHEBI:30009" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_019668
xref: Alzforum_mut:mapt-k369i
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037551
name: microtubule-associated protein tau sequence variant G389R (human)
def: "A microtubule-associated protein tau sequence variant (human) that has an Arg residue at the position equivalent to Gly-389 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Gly-706 in PNS-Tau). Example: UniProtKB:P10636-8, Gly-389, CHEBI:29952." [Alzforum:KD, PMID:10604746, PMID:11117542, PMID:11193177, PMID:18307268, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_010352 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:G389R" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Gly-389, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_010352
xref: Alzforum_mut:mapt-g389r-ga
xref: Alzforum_mut:mapt-g389r-gc
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037552
name: microtubule-associated protein tau sequence variant R406W (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Trp residue at the position equivalent to Arg-406 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Arg-723 in PNS-Tau). Example: UniProtKB:P10636-8, Arg-406, CHEBI:29954." [Alzforum:KD, PMID:9382464, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_010353 is with respect to PNS-Tau numbering.
synonym: "hMAPT/var:R406W" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Arg-406, CHEBI:29954" NARROW PRO-proteoform-std [PRO:DNx]
xref: UniProtKB_VAR:VAR_010353
xref: Alzforum_mut:mapt-r406w
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037553
name: microtubule-associated protein tau sequence variant N410H (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a His residue at the position equivalent to Asn-410 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Asn-727 in PNS-Tau). Example: UniProtKB:P10636-8, Asn-410, CHEBI:29979." [Alzforum:KD, PMID:24121548, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:N410H" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Asn-410, CHEBI:29979" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-n410h
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037554
name: microtubule-associated protein tau sequence variant T427M (human)
def: "A microtubule-associated protein tau sequence variant (human) that has a Met residue at the position equivalent to Thr-427 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Thr-744 in PNS-Tau). Example: UniProtKB:P10636-8, Thr-427, CHEBI:16044." [Alzforum:KD, PMID:15940384, PRO:DAN]
comment: Category=organism-sequence. Requested by=Alzforum.
synonym: "hMAPT/var:T427M" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P10636-8, Thr-427, CHEBI:16044" NARROW PRO-proteoform-std [PRO:DNx]
xref: Alzforum_mut:mapt-t427m
is_a: PR:000028708 ! microtubule-associated protein tau sequence variant (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens