[Term]
id: PR:P15018
name: leukemia inhibitory factor (human)
def: "A leukemia inhibitory factor that is encoded in the genome of human." [PRO:DNx, UniProtKB:P15018]
comment: Category=organism-gene.
synonym: "LIF" RELATED Gene-based [UniProtKB:P15018]
synonym: "hLIF" EXACT PRO-short-label [PRO:DNx]
synonym: "HILDA" RELATED Gene-based [UniProtKB:P15018]
synonym: "MLPLI (human)" EXACT [UniProtKB:P15018]
synonym: "D factor (human)" EXACT [UniProtKB:P15018]
synonym: "emfilermin (human)" EXACT [UniProtKB:P15018]
synonym: "melanoma-derived LPL inhibitor (human)" EXACT [UniProtKB:P15018]
synonym: "differentiation-stimulating factor (human)" EXACT [UniProtKB:P15018]
xref: UniProtKB:P15018
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000009799 ! leukemia inhibitory factor
relationship: has_gene_template HGNC:6596 ! LIF (human)

[Term]
id: PR:P15018-1
name: leukemia inhibitory factor isoform 1 (human)
def: "A leukemia inhibitory factor isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hLIF/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P15018-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038919 ! leukemia inhibitory factor isoform 1

[Term]
id: PR:P15018-2
name: leukemia inhibitory factor isoform h2 (human)
def: "A leukemia inhibitory factor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15018-2." [PRO:DNx, UniProtKB:P15018]
comment: Category=organism-sequence.
synonym: "hLIF/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P15018-2
is_a: PR:P15018 ! leukemia inhibitory factor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048197
name: leukemia inhibitory factor, signal peptide removed form (human)
def: "A leukemia inhibitory factor (human) that has had the signal peptide removed. UniProtKB:P15018, 23-202." [PRO:DNx, Reactome:R-HSA-5696436]
comment: Category=organism-modification.
synonym: "hLIF/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000017715" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P15018, 23-202" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5696436 "PR:000048197 located_in GO:0005576"
intersection_of: PR:P15018 ! leukemia inhibitory factor (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000009799
name: leukemia inhibitory factor
def: "A protein that is a translation product of the human LIF gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "LIF" EXACT PRO-short-label [PRO:DNx]
synonym: "HILDA" RELATED Gene-based []
synonym: "MLPLI" EXACT []
synonym: "D factor" EXACT []
synonym: "emfilermin" EXACT []
synonym: "melanoma-derived LPL inhibitor" EXACT []
synonym: "differentiation-stimulating factor" EXACT []
is_a: PR:000000001 ! protein