[Term]
id: PR:000028616
name: transcription factor Jun isoform 1 acetylated 1 (human)
def: "A transcription factor Jun isoform 1 acetylated 1 in human. UniProtKB:P05412-1, Lys-268/Lys-271/Lys-273, MOD:00064." [KAT:P05412, PMID:18793328, PRO:PD]
comment: Category=organism-modification. Acetylase=("EP300"; PR:000007102).
synonym: "hJUN/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P05412-1, Lys-268/Lys-271/Lys-273, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000028615 ! transcription factor Jun isoform 1 acetylated 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:000009232
name: transcription factor Jun
def: "A protein that is a translation product of the human JUN gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "AP1" EXACT []
synonym: "JUN" EXACT PRO-short-label [PRO:DNx]
synonym: "p39" BROAD [PRO:DNx]
synonym: "AH119" EXACT []
synonym: "jun A" EXACT []
synonym: "activator protein 1" EXACT []
synonym: "proto-oncogene c-Jun" EXACT []
synonym: "transcription factor AP-1 subunit Jun" EXACT []
synonym: "V-jun avian sarcoma virus 17 oncogene homolog" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000025892
name: transcription factor Jun isoform 1 phosphorylated 1 (mouse)
def: "A transcription factor Jun isoform 1 phosphorylated 1 in mouse. UniProtKB:P05627-1, Ser-63/Ser-73, MOD:00046|MOD:00696." [PMID:19144319, PMID:20516211, PRO:HJD]
comment: Category=organism-modification.
synonym: "mJUN/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P05627-1, Ser-63/Ser-73, MOD:00046|MOD:00696" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:000025891 ! transcription factor Jun isoform 1 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00696 ! phosphorylated residue
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000048089
name: transcription factor Jun phosphorylated 2 (human)
def: "A transcription factor Jun (human) that has been post-translationally modified to include phosphoserine at positions 63 and 73 of the amino acid sequence represented by UniProtKB:P05412. UniProtKB:P05412, Ser-63/Ser-73, MOD:00046." [PRO:DNx, Reactome:R-HSA-450237]
comment: Category=organism-modification.
synonym: "hJUN/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P05412, Ser-63/Ser-73, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-450237 "PR:000048089 located_in GO:0005654"
xref: Reactome:R-HSA-8868682 "PR:000048089 located_in GO:0005829"
is_a: PR:P05412 ! transcription factor Jun (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000025890
name: transcription factor Jun isoform 1
def: "A transcription factor Jun that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05627-1 or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=sequence.
synonym: "JUN/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000009232 ! transcription factor Jun

[Term]
id: PR:000025891
name: transcription factor Jun isoform 1 phosphorylated 1
def: "A transcription factor Jun isoform 1 that has been phosphorylated in the N-terminal transactivation domain." [PMID:11057897, PRO:CNA, PRO:DAN]
comment: Category=modification.
synonym: "JUN/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000025890 ! transcription factor Jun isoform 1
relationship: has_part MOD:00696 ! phosphorylated residue

[Term]
id: PR:P05412
name: transcription factor Jun (human)
def: "A transcription factor Jun that is encoded in the genome of human." [PRO:DNx, UniProtKB:P05412]
comment: Category=organism-gene.
synonym: "JUN" RELATED Gene-based [UniProtKB:P05412]
synonym: "hJUN" EXACT PRO-short-label [PRO:DNx]
synonym: "AP1 (human)" EXACT [UniProtKB:P05412]
synonym: "p39 (human)" BROAD [UniProtKB:P05412]
synonym: "activator protein 1 (human)" EXACT [UniProtKB:P05412]
synonym: "proto-oncogene c-Jun (human)" EXACT [UniProtKB:P05412]
synonym: "transcription factor AP-1 subunit Jun (human)" EXACT [UniProtKB:P05412]
synonym: "V-jun avian sarcoma virus 17 oncogene homolog (human)" EXACT [UniProtKB:P05412]
xref: Reactome:R-HSA-168194 "PR:P05412 located_in GO:0005829"
xref: Reactome:R-HSA-450250 "PR:P05412 located_in GO:0005654"
xref: UniProtKB:P05412
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000009232 ! transcription factor Jun
relationship: has_gene_template HGNC:6204 ! JUN (human)

[Term]
id: PR:000028615
name: transcription factor Jun isoform 1 acetylated 1
def: "A transcription factor Jun isoform 1 that is acetylated on Lys residues located in a basic, positively charged domain (DNA binding domain) towards the C-terminus. Example: UniProtKB:P05412-1, Lys-268/Lys-271/Lys-273, MOD:00064." [KAT:P05412, PMID:18793328, PRO:PD]
comment: Category=modification.
synonym: "JUN/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000025890 ! transcription factor Jun isoform 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:P05412-1
name: transcription factor Jun isoform 1 (human)
def: "A transcription factor Jun isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hJUN/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P05412-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025890 ! transcription factor Jun isoform 1

[Term]
id: PR:000045641
name: transcription factor Jun phosphorylated 1 (human)
def: "A transcription factor Jun (human) that has been phosphorylated at Tyr-170. UniProtKB:P05412, Tyr-170, MOD:00048." [PMID:10637231, iPTMnet:P05412]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:10637231). Status=unreviewed.
synonym: "hJUN/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P05412, Tyr-170, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P05412 ! transcription factor Jun (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P05627-1
name: transcription factor Jun isoform 1 (mouse)
def: "A transcription factor Jun isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mJUN/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P05627-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000025890 ! transcription factor Jun isoform 1

[Term]
id: PR:P05627
name: transcription factor Jun (mouse)
def: "A transcription factor Jun that is encoded in the genome of mouse." [OMA:P05627, PRO:DNx]
comment: Category=organism-gene.
synonym: "Jun" RELATED Gene-based [UniProtKB:P05627]
synonym: "mJUN" EXACT PRO-short-label [PRO:DNx]
synonym: "AP1 (mouse)" EXACT [UniProtKB:P05627]
synonym: "AH119 (mouse)" EXACT [UniProtKB:P05627]
synonym: "Jun A (mouse)" EXACT [UniProtKB:P05627]
synonym: "activator protein 1 (mouse)" EXACT [UniProtKB:P05627]
synonym: "proto-oncogene c-Jun (mouse)" EXACT [UniProtKB:P05627]
synonym: "transcription factor AP-1 subunit Jun (mouse)" EXACT [UniProtKB:P05627]
synonym: "V-jun avian sarcoma virus 17 oncogene homolog (mouse)" EXACT [UniProtKB:P05627]
xref: UniProtKB:P05627
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000009232 ! transcription factor Jun
relationship: has_gene_template MGI:96646 ! Jun (mouse)

[Term]
id: PR:P18870
name: transcription factor Jun (chicken)
def: "A transcription factor Jun that is encoded in the genome of chicken." [OMA:P18870, PRO:DNx]
comment: Category=organism-gene.
synonym: "JUN" RELATED Gene-based [UniProtKB:P18870]
synonym: "chick-JUN" EXACT PRO-short-label [PRO:DNx]
synonym: "proto-oncogene c-Jun (chicken)" EXACT [UniProtKB:P18870]
synonym: "transcription factor AP-1 subunit Jun (chicken)" EXACT [UniProtKB:P18870]
xref: UniProtKB:P18870
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000009232 ! transcription factor Jun
relationship: has_gene_template NCBIGene:424673 ! JUN (chicken)

[Term]
id: PR:P17325
name: transcription factor Jun (rat)
def: "A transcription factor Jun that is encoded in the genome of rat." [OMA:P17325, PANTHER:PTHR11462:SF8, PRO:DNx]
comment: Category=organism-gene.
synonym: "Jun" RELATED Gene-based [UniProtKB:P17325]
synonym: "rJUN" EXACT PRO-short-label [PRO:DNx]
synonym: "Rjg-9" RELATED Gene-based [UniProtKB:P17325]
synonym: "AP1 (rat)" EXACT [UniProtKB:P17325]
synonym: "activator protein 1 (rat)" EXACT [UniProtKB:P17325]
synonym: "proto-oncogene c-Jun (rat)" EXACT [UniProtKB:P17325]
synonym: "transcription factor AP-1 subunit Jun (rat)" EXACT [UniProtKB:P17325]
synonym: "V-jun avian sarcoma virus 17 oncogene homolog (rat)" EXACT [UniProtKB:P17325]
xref: UniProtKB:P17325
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000009232 ! transcription factor Jun
relationship: has_gene_template RGD:2943 ! Jun (rat)