[Term]
id: PR:P70389
name: insulin-like growth factor-binding protein complex acid labile subunit (mouse)
def: "An insulin-like growth factor-binding protein complex acid labile chain that is encoded in the genome of mouse." [OMA:P70389, PRO:DNx]
comment: Category=organism-gene.
synonym: "Als" RELATED Gene-based [UniProtKB:P70389]
synonym: "Albs" RELATED Gene-based [UniProtKB:P70389]
synonym: "Igfals" RELATED Gene-based [UniProtKB:P70389]
synonym: "mIGFALS" EXACT PRO-short-label [PRO:DNx]
synonym: "ALS (mouse)" EXACT [UniProtKB:P70389]
xref: UniProtKB:P70389
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008946 ! insulin-like growth factor-binding protein complex acid labile chain
relationship: has_gene_template MGI:107973 ! Igfals (mouse)

[Term]
id: PR:000008946
name: insulin-like growth factor-binding protein complex acid labile chain
def: "A protein that is a translation product of the human IGFALS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ALS" RELATED Gene-based []
synonym: "Albs" RELATED Gene-based []
synonym: "IGFALS" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:P35859-1
name: insulin-like growth factor-binding protein complex acid labile subunit isoform 1 (rat)
def: "An insulin-like growth factor-binding protein complex acid labile chain isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rIGFALS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35859-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000040122 ! insulin-like growth factor-binding protein complex acid labile chain isoform 1

[Term]
id: PR:000056407
name: insulin-like growth factor-binding protein complex acid labile subunit O-glycosylated 1 (human)
def: "An insulin-like growth factor-binding protein complex acid labile subunit (human) that has been O-glycosylated at the residue equivalent to Thr-32 of the amino acid sequence represented by UniProtKB:P35858-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P35858-1, Thr-32, MOD:00005~GNO:G43417UB." [GlyGen:P35858-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hIGFALS/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P35858-1, Thr-32, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P35858 ! insulin-like growth factor-binding protein complex acid labile subunit (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000020269
name: insulin-like growth factor-binding protein complex acid labile chain, signal peptide removed form
def: "An insulin-like growth factor-binding protein complex acid labile chain that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "IGFALS/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000008946 ! insulin-like growth factor-binding protein complex acid labile chain
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000040122
name: insulin-like growth factor-binding protein complex acid labile chain isoform 1
def: "An insulin-like growth factor-binding protein complex acid labile chain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70389-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "IGFALS/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008946 ! insulin-like growth factor-binding protein complex acid labile chain

[Term]
id: PR:P35858
name: insulin-like growth factor-binding protein complex acid labile subunit (human)
def: "An insulin-like growth factor-binding protein complex acid labile chain that is encoded in the genome of human." [PRO:DNx, UniProtKB:P35858]
comment: Category=organism-gene.
synonym: "ALS" RELATED Gene-based [UniProtKB:P35858]
synonym: "IGFALS" RELATED Gene-based [UniProtKB:P35858]
synonym: "hIGFALS" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35858
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008946 ! insulin-like growth factor-binding protein complex acid labile chain
relationship: has_gene_template HGNC:5468 ! IGFALS (human)

[Term]
id: PR:P35859
name: insulin-like growth factor-binding protein complex acid labile subunit (rat)
def: "An insulin-like growth factor-binding protein complex acid labile chain that is encoded in the genome of rat." [PANTHER:PTHR24365:SF135, PRO:DNx]
comment: Category=organism-gene.
synonym: "Als" RELATED Gene-based [UniProtKB:P35859]
synonym: "Igfals" RELATED Gene-based [UniProtKB:P35859]
synonym: "rIGFALS" EXACT PRO-short-label [PRO:DNx]
synonym: "ALS (rat)" EXACT [UniProtKB:P35859]
xref: UniProtKB:P35859
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000008946 ! insulin-like growth factor-binding protein complex acid labile chain
relationship: has_gene_template RGD:68429 ! Igfals (rat)

[Term]
id: PR:P70389-1
name: insulin-like growth factor-binding protein complex acid labile subunit isoform 1 (mouse)
def: "An insulin-like growth factor-binding protein complex acid labile chain isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mIGFALS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P70389-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040122 ! insulin-like growth factor-binding protein complex acid labile chain isoform 1

[Term]
id: PR:P35858-2
name: insulin-like growth factor-binding protein complex acid labile subunit isoform h2 (human)
def: "An insulin-like growth factor-binding protein complex acid labile subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35858-2." [PRO:DNx, UniProtKB:P35858]
comment: Category=organism-sequence.
synonym: "hIGFALS/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35858-2
is_a: PR:P35858 ! insulin-like growth factor-binding protein complex acid labile subunit (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P35858-1
name: insulin-like growth factor-binding protein complex acid labile subunit isoform h1 (human)
def: "An insulin-like growth factor-binding protein complex acid labile subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35858-1." [PRO:DNx, UniProtKB:P35858]
comment: Category=organism-sequence.
synonym: "hIGFALS/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35858-1
is_a: PR:P35858 ! insulin-like growth factor-binding protein complex acid labile subunit (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047972
name: insulin-like growth factor-binding protein complex acid labile subunit, signal peptide removed form (human)
def: "An insulin-like growth factor-binding protein complex acid labile subunit (human) that has had the signal peptide removed. UniProtKB:P35858, 28-605." [PRO:DNx, Reactome:R-HSA-381498]
comment: Category=organism-modification.
synonym: "PRO_0000020695" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hIGFALS/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P35858, 28-605" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-381498 "PR:000047972 located_in GO:0005576"
intersection_of: PR:P35858 ! insulin-like growth factor-binding protein complex acid labile subunit (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens