[Term]
id: PR:Q8BU30
name: isoleucine--tRNA ligase, cytoplasmic (mouse)
def: "An isoleucine--tRNA ligase, cytoplasmic that is encoded in the genome of mouse." [OMA:Q8BU30, PRO:DNx]
comment: Category=organism-gene.
synonym: "Iars" RELATED Gene-based [UniProtKB:Q8BU30]
synonym: "Iars1" RELATED Gene-based [UniProtKB:Q8BU30]
synonym: "mIARS" EXACT PRO-short-label [PRO:DNx]
synonym: "IRS (mouse)" BROAD [PRO:DAN, UniProtKB:Q8BU30]
synonym: "IleRS (mouse)" BROAD [PRO:DAN, UniProtKB:Q8BU30]
synonym: "isoleucine--tRNA ligase (mouse)" BROAD [PRO:DAN]
synonym: "isoleucyl-tRNA synthetase (mouse)" BROAD [PRO:DAN, UniProtKB:Q8BU30]
synonym: "isoleucyl-tRNA synthetase, cytoplasmic (mouse)" EXACT [PRO:DAN]
xref: UniProtKB:Q8BU30
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008876 ! isoleucine--tRNA ligase, cytoplasmic
relationship: has_gene_template MGI:2145219 ! Iars (mouse)

[Term]
id: PR:P41252
name: isoleucine--tRNA ligase, cytoplasmic (human)
def: "An isoleucine--tRNA ligase, cytoplasmic that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-gene.
synonym: "IARS" RELATED Gene-based [UniProtKB:P41252]
synonym: "IARS1" RELATED Gene-based [UniProtKB:P41252]
synonym: "hIARS1" EXACT PRO-short-label [PRO:DNx]
synonym: "IRS (human)" EXACT [UniProtKB:P41252]
synonym: "IleRS (human)" BROAD [PRO:DAN]
synonym: "isoleucine--tRNA ligase (human)" BROAD [PRO:DAN]
synonym: "isoleucyl-tRNA synthetase (human)" BROAD [PRO:DAN]
xref: Reactome:R-HSA-379641 "PR:P41252 located_in GO:0005829"
xref: UniProtKB:P41252
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008876 ! isoleucine--tRNA ligase, cytoplasmic
relationship: has_gene_template HGNC:5330 ! IARS1 (human)

[Term]
id: PR:F4JLM5
name: isoleucine--tRNA ligase, cytoplasmic (Arabidopsis thaliana)
def: "An isoleucine--tRNA ligase, cytoplasmic that is encoded in the genome of Arabidopsis thaliana." [OMA:F4JLM5, PRO:DNx]
comment: Category=organism-gene.
synonym: "At-IARS" EXACT PRO-short-label [PRO:DNx]
synonym: "At4g10320" RELATED Gene-based [UniProtKB:F4JLM5]
synonym: "IleRS (Arabidopsis thaliana)" BROAD [PRO:DAN, UniProtKB:F4JLM5]
synonym: "isoleucine--tRNA ligase (Arabidopsis thaliana)" BROAD [PRO:DAN]
synonym: "isoleucyl-tRNA synthetase (Arabidopsis thaliana)" BROAD [PRO:DAN, UniProtKB:F4JLM5]
synonym: "isoleucyl-tRNA synthetase, cytoplasmic (Arabidopsis thaliana)" EXACT [PRO:DAN]
xref: UniProtKB:F4JLM5
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000008876 ! isoleucine--tRNA ligase, cytoplasmic
relationship: has_gene_template Araport:AT4G10320 ! At4g10320 (Arabidopsis thaliana)

[Term]
id: PR:P41252-1
name: isoleucine--tRNA ligase, cytoplasmic isoform 1 (human)
def: "An isoleucine--tRNA ligase, cytoplasmic isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hIARS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P41252-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039423 ! isoleucine--tRNA ligase, cytoplasmic isoform 1

[Term]
id: PR:Q21926
name: isoleucine--tRNA ligase, cytoplasmic (worm)
def: "An isoleucine--tRNA ligase, cytoplasmic that is encoded in the genome of worm." [OMA:Q21926, PRO:DNx]
comment: Category=organism-gene.
synonym: "irs-1" RELATED Gene-based [UniProtKB:Q21926]
synonym: "iars-1" RELATED Gene-based [UniProtKB:Q21926]
synonym: "R11A8.6" RELATED Gene-based [UniProtKB:Q21926]
synonym: "IARS (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "IleRS (worm)" BROAD [PRO:DAN, UniProtKB:Q21926]
synonym: "isoleucine--tRNA ligase (worm)" BROAD [PRO:DAN]
synonym: "isoleucyl-tRNA synthetase (worm)" BROAD [PRO:DAN, UniProtKB:Q21926]
synonym: "isoleucyl-tRNA synthetase, cytoplasmic (worm)" EXACT [PRO:DAN]
xref: UniProtKB:Q21926
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000008876 ! isoleucine--tRNA ligase, cytoplasmic
relationship: has_gene_template WormBase:WBGene00002152 ! iars-1 (worm)

[Term]
id: PR:P09436
name: isoleucine--tRNA ligase, cytoplasmic (yeast)
def: "An isoleucine--tRNA ligase, cytoplasmic that is encoded in the genome of yeast." [OMA:P09436, PRO:DNx]
comment: Category=organism-gene.
synonym: "ILS1" RELATED Gene-based [UniProtKB:P09436]
synonym: "yIARS" EXACT PRO-short-label [PRO:DNx]
synonym: "YBL0734" RELATED Gene-based [UniProtKB:P09436]
synonym: "YBL076C" RELATED Gene-based [UniProtKB:P09436]
synonym: "IleRS (yeast)" BROAD [PRO:DAN, UniProtKB:P09436]
synonym: "isoleucine--tRNA ligase (yeast)" BROAD [PRO:DAN]
synonym: "isoleucyl-tRNA synthetase (yeast)" BROAD [PRO:DAN, UniProtKB:P09436]
synonym: "isoleucyl-tRNA synthetase, cytoplasmic (yeast)" EXACT [PRO:DAN]
xref: UniProtKB:P09436
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000008876 ! isoleucine--tRNA ligase, cytoplasmic
relationship: has_gene_template SGD:S000000172 ! ILS1 (yeast)

[Term]
id: PR:000008876
name: isoleucine--tRNA ligase, cytoplasmic
def: "A protein that is a translation product of the human IARS1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "IRS" EXACT []
synonym: "IARS" RELATED Gene-based []
synonym: "IARS1" EXACT PRO-short-label [PRO:DNx]
synonym: "IleRS" BROAD [PRO:DAN]
synonym: "isoleucine--tRNA ligase" BROAD [PRO:DAN]
synonym: "isoleucyl-tRNA synthetase" BROAD [PRO:DAN]
synonym: "isoleucyl-tRNA synthetase, cytoplasmic" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:O13651
name: isoleucine--tRNA ligase, cytoplasmic (Schizosaccharomyces pombe 972h-)
def: "An isoleucine--tRNA ligase, cytoplasmic that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O13651, PRO:DNx]
comment: Category=organism-gene.
synonym: "irs1" RELATED Gene-based [UniProtKB:O13651]
synonym: "pi058" RELATED Gene-based [UniProtKB:O13651]
synonym: "SPBC8D2.06" RELATED Gene-based [UniProtKB:O13651]
synonym: "Spom972h-IARS" EXACT PRO-short-label [PRO:DNx]
synonym: "IleRS (Schizosaccharomyces pombe 972h-)" BROAD [PRO:DAN, UniProtKB:O13651]
synonym: "isoleucine--tRNA ligase (Schizosaccharomyces pombe 972h-)" BROAD [PRO:DAN]
synonym: "isoleucyl-tRNA synthetase (Schizosaccharomyces pombe 972h-)" BROAD [PRO:DAN, UniProtKB:O13651]
synonym: "isoleucyl-tRNA synthetase, cytoplasmic (Schizosaccharomyces pombe 972h-)" EXACT [PRO:DAN]
xref: UniProtKB:O13651
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000008876 ! isoleucine--tRNA ligase, cytoplasmic
relationship: has_gene_template PomBase:SPBC8D2.06 ! irs1 (Schizosaccharomyces pombe)

[Term]
id: PR:Q8BU30-1
name: isoleucine--tRNA ligase, cytoplasmic isoform 1 (mouse)
def: "An isoleucine--tRNA ligase, cytoplasmic isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mIARS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8BU30-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039423 ! isoleucine--tRNA ligase, cytoplasmic isoform 1

[Term]
id: PR:000039423
name: isoleucine--tRNA ligase, cytoplasmic isoform 1
def: "An isoleucine--tRNA ligase, cytoplasmic that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41252-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "IARS/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008876 ! isoleucine--tRNA ligase, cytoplasmic

[Term]
id: PR:Q54YD4
name: probable isoleucine--tRNA ligase, cytoplasmic (Dictyostelium discoideum)
def: "An isoleucine--tRNA ligase, cytoplasmic that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54YD4, PRO:DNx]
comment: Category=organism-gene.
synonym: "ileS" RELATED Gene-based [UniProtKB:Q54YD4]
synonym: "Dicty-IARS" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0278293" RELATED Gene-based [UniProtKB:Q54YD4]
synonym: "IRS (Dictyostelium discoideum)" BROAD [PRO:DAN, UniProtKB:Q54YD4]
synonym: "IleRS (Dictyostelium discoideum)" BROAD [PRO:DAN, UniProtKB:Q54YD4]
synonym: "isoleucine--tRNA ligase (Dictyostelium discoideum)" BROAD [PRO:DAN]
synonym: "isoleucyl-tRNA synthetase (Dictyostelium discoideum)" BROAD [PRO:DAN, UniProtKB:Q54YD4]
synonym: "isoleucyl-tRNA synthetase, cytoplasmic (Dictyostelium discoideum)" EXACT [PRO:DAN]
xref: UniProtKB:Q54YD4
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000008876 ! isoleucine--tRNA ligase, cytoplasmic
relationship: has_gene_template dictyBase:DDB_G0278293 ! ileS (Dictyostelium discoideum)