[Term]
id: PR:000008875
name: islet amyloid polypeptide
def: "A protein that is a translation product of the human IAPP gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "DAP" BROAD [PRO:DNx]
synonym: "IAPP" EXACT PRO-short-label [PRO:DNx]
synonym: "amylin" EXACT []
synonym: "insulinoma amyloid peptide" EXACT []
synonym: "diabetes-associated peptide" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P10997
name: islet amyloid polypeptide (human)
def: "An islet amyloid polypeptide that is encoded in the genome of human." [PRO:DNx, UniProtKB:P10997]
comment: Category=organism-gene.
synonym: "IAPP" RELATED Gene-based [UniProtKB:P10997]
synonym: "hIAPP" EXACT PRO-short-label [PRO:DNx]
synonym: "DAP (human)" EXACT [UniProtKB:P10997]
synonym: "amylin (human)" EXACT [UniProtKB:P10997]
synonym: "insulinoma amyloid peptide (human)" EXACT [UniProtKB:P10997]
synonym: "diabetes-associated peptide (human)" EXACT [UniProtKB:P10997]
xref: Reactome:R-HSA-186631 "PR:P10997 located_in GO:0005829"
xref: UniProtKB:P10997
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008875 ! islet amyloid polypeptide
relationship: has_gene_template HGNC:5329 ! IAPP (human)

[Term]
id: PR:P12969
name: islet amyloid polypeptide (rat)
def: "An islet amyloid polypeptide that is encoded in the genome of rat." [OMA:P12969, PANTHER:PTHR10505:SF4, PRO:DNx]
comment: Category=organism-gene.
synonym: "Iapp" RELATED Gene-based [UniProtKB:P12969]
synonym: "rIAPP" EXACT PRO-short-label [PRO:DNx]
synonym: "DAP (rat)" RELATED [UniProtKB:P12969]
synonym: "amylin (rat)" EXACT [UniProtKB:P12969]
synonym: "diabetes-associated peptide (rat)" EXACT [UniProtKB:P12969]
xref: UniProtKB:P12969
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000008875 ! islet amyloid polypeptide
relationship: has_gene_template RGD:2854 ! Iapp (rat)

[Term]
id: PR:P12968
name: islet amyloid polypeptide (mouse)
def: "An islet amyloid polypeptide that is encoded in the genome of mouse." [OMA:P12968, PRO:DNx]
comment: Category=organism-gene.
synonym: "Iapp" RELATED Gene-based [UniProtKB:P12968]
synonym: "mIAPP" EXACT PRO-short-label [PRO:DNx]
synonym: "DAP (mouse)" EXACT [UniProtKB:P12968]
synonym: "amylin (mouse)" EXACT [UniProtKB:P12968]
synonym: "diabetes-associated peptide (mouse)" EXACT [UniProtKB:P12968]
xref: UniProtKB:P12968
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008875 ! islet amyloid polypeptide
relationship: has_gene_template MGI:96382 ! Iapp (mouse)

[Term]
id: PR:000020226
name: islet amyloid polypeptide proteolytic cleavage product
def: "An islet amyloid polypeptide that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "IAPP/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000008875 ! islet amyloid polypeptide

[Term]
id: PR:000038869
name: islet amyloid polypeptide isoform 1
def: "An islet amyloid polypeptide that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12968-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "IAPP/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008875 ! islet amyloid polypeptide

[Term]
id: PR:P12968-1
name: islet amyloid polypeptide isoform 1 (mouse)
def: "An islet amyloid polypeptide isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mIAPP/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P12968-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038869 ! islet amyloid polypeptide isoform 1

[Term]
id: PR:P12969-1
name: islet amyloid polypeptide isoform 1 (rat)
def: "An islet amyloid polypeptide isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rIAPP/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P12969-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000038869 ! islet amyloid polypeptide isoform 1