[Term]
id: PR:Q0VCX2
name: endoplasmic reticulum chaperone BiP (cow)
def: "An endoplasmic reticulum chaperone BiP that is encoded in the genome of cow." [OMA:Q0VCX2, PRO:DAN]
comment: Category=organism-gene.
synonym: "GRP78" RELATED Gene-based [UniProtKB:Q0VCX2]
synonym: "HSPA5" RELATED Gene-based [UniProtKB:Q0VCX2]
synonym: "BiP (cow)" EXACT [UniProtKB:Q0VCX2]
synonym: "cow-HSPA5" EXACT PRO-short-label [PRO:DNx]
synonym: "GRP-78 (cow)" EXACT [UniProtKB:Q0VCX2]
synonym: "HSP70 family protein 5 (cow)" EXACT [UniProtKB:Q0VCX2]
synonym: "binding-immunoglobulin protein (cow)" EXACT [UniProtKB:Q0VCX2]
synonym: "78 kDa glucose-regulated protein (cow)" EXACT [UniProtKB:Q0VCX2]
synonym: "heat shock protein family A member 5 (cow)" EXACT [UniProtKB:Q0VCX2]
synonym: "heat shock protein 70 family protein 5 (cow)" EXACT [UniProtKB:Q0VCX2]
synonym: "immunoglobulin heavy chain-binding protein (cow)" EXACT [UniProtKB:Q0VCX2]
xref: UniProtKB:Q0VCX2
intersection_of: only_in_taxon NCBITaxon:9913 ! Bos taurus
intersection_of: PR:000008810 ! endoplasmic reticulum chaperone BiP
relationship: has_gene_template NCBIGene:415113 ! HSPA5 (cow)

[Term]
id: PR:P36604
name: endoplasmic reticulum chaperone BiP (Schizosaccharomyces pombe 972h-)
def: "An endoplasmic reticulum chaperone BiP that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:P36604, PRO:DNx]
comment: Category=organism-gene.
synonym: "bip" RELATED Gene-based [UniProtKB:P36604]
synonym: "bip1" RELATED Gene-based [UniProtKB:P36604]
synonym: "SPAC22A12.15c" RELATED Gene-based [UniProtKB:P36604]
synonym: "Spom972h-HSPA5" EXACT PRO-short-label [PRO:DNx]
synonym: "BiP (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P36604]
synonym: "immunoglobulin heavy chain-binding protein homolog (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P36604]
xref: UniProtKB:P36604
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000008810 ! endoplasmic reticulum chaperone BiP
relationship: has_gene_template PomBase:SPAC22A12.15c ! bip1 (Schizosaccharomyces pombe)

[Term]
id: PR:P16474
name: endoplasmic reticulum chaperone BiP (yeast)
def: "An endoplasmic reticulum chaperone BiP that is encoded in the genome of yeast." [OMA:P16474, PRO:DNx]
comment: Category=organism-gene.
synonym: "KAR2" RELATED Gene-based [UniProtKB:P16474]
synonym: "SSD1" RELATED Gene-based [UniProtKB:P16474]
synonym: "GRP78" RELATED Gene-based [UniProtKB:P16474]
synonym: "J1248" RELATED Gene-based [UniProtKB:P16474]
synonym: "yHSPA5" EXACT PRO-short-label [PRO:DNx]
synonym: "YJL034W" RELATED Gene-based [UniProtKB:P16474]
synonym: "BiP (yeast)" EXACT [UniProtKB:P16474]
synonym: "GRP-78 (yeast)" EXACT [UniProtKB:P16474]
synonym: "78 kDa glucose-regulated protein homolog (yeast)" EXACT [UniProtKB:P16474]
synonym: "immunoglobulin heavy chain-binding protein homolog (yeast)" EXACT [UniProtKB:P16474]
xref: UniProtKB:P16474
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000008810 ! endoplasmic reticulum chaperone BiP
relationship: has_gene_template SGD:S000003571 ! KAR2 (yeast)

[Term]
id: PR:P11021
name: endoplasmic reticulum chaperone BiP (human)
def: "An endoplasmic reticulum chaperone BiP that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-gene.
synonym: "GRP78" RELATED Gene-based [UniProtKB:P11021]
synonym: "HSPA5" RELATED Gene-based [UniProtKB:P11021]
synonym: "hHSPA5" EXACT PRO-short-label [PRO:DNx]
synonym: "BiP (human)" EXACT [UniProtKB:P11021]
synonym: "GRP-78 (human)" EXACT [UniProtKB:P11021]
synonym: "HSP70 family protein 5 (human)" EXACT [UniProtKB:P11021]
synonym: "binding-immunoglobulin protein (human)" EXACT [UniProtKB:P11021]
synonym: "78 kDa glucose-regulated protein (human)" EXACT [UniProtKB:P11021]
synonym: "heat shock protein family A member 5 (human)" EXACT [UniProtKB:P11021]
synonym: "heat shock protein 70 family protein 5 (human)" EXACT [UniProtKB:P11021]
synonym: "immunoglobulin heavy chain-binding protein (human)" EXACT [UniProtKB:P11021]
xref: UniProtKB:P11021
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008810 ! endoplasmic reticulum chaperone BiP
relationship: has_gene_template HGNC:5238 ! HSPA5 (human)

[Term]
id: PR:P29844
name: endoplasmic reticulum chaperone BiP (fruit fly)
def: "An endoplasmic reticulum chaperone BiP that is encoded in the genome of fruit fly." [OMA:P29844, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hsc3" RELATED Gene-based [UniProtKB:P29844]
synonym: "CG4147" RELATED Gene-based [UniProtKB:P29844]
synonym: "Hsc70-3" RELATED Gene-based [UniProtKB:P29844]
synonym: "fly-HSPA5" EXACT PRO-short-label [PRO:DNx]
synonym: "BiP (fruit fly)" EXACT [UniProtKB:P29844]
synonym: "GRP-78 homolog (fruit fly)" EXACT [UniProtKB:P29844]
synonym: "heat shock protein cognate 72 (fruit fly)" EXACT [UniProtKB:P29844]
synonym: "heat shock 70 kDa protein cognate 3 (fruit fly)" EXACT [UniProtKB:P29844]
synonym: "binding-immunoglobulin protein homolog (fruit fly)" EXACT [UniProtKB:P29844]
synonym: "78 kDa glucose-regulated protein homolog (fruit fly)" EXACT [UniProtKB:P29844]
xref: UniProtKB:P29844
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000008810 ! endoplasmic reticulum chaperone BiP
relationship: has_gene_template FlyBase:FBgn0001218 ! Hsc70-3 (fruit fly)

[Term]
id: PR:Q90593
name: endoplasmic reticulum chaperone BiP (chicken)
def: "An endoplasmic reticulum chaperone BiP that is encoded in the genome of chicken." [OMA:Q90593, PRO:DAN]
comment: Category=organism-gene.
synonym: "GRP78" RELATED Gene-based [UniProtKB:Q90593]
synonym: "HSPA5" RELATED Gene-based [UniProtKB:Q90593]
synonym: "chick-HSPA5" EXACT PRO-short-label [PRO:DNx]
synonym: "BiP (chicken)" EXACT [UniProtKB:Q90593]
synonym: "GRP-78 (chicken)" EXACT [UniProtKB:Q90593]
synonym: "HSP70 family protein 5 (chicken)" EXACT [UniProtKB:Q90593]
synonym: "binding-immunoglobulin protein (chicken)" EXACT [UniProtKB:Q90593]
synonym: "78 kDa glucose-regulated protein (chicken)" EXACT [UniProtKB:Q90593]
synonym: "heat shock protein family A member 5 (chicken)" EXACT [UniProtKB:Q90593]
synonym: "heat shock protein 70 family protein 5 (chicken)" EXACT [UniProtKB:Q90593]
synonym: "immunoglobulin heavy chain-binding protein (chicken)" EXACT [UniProtKB:Q90593]
xref: UniProtKB:Q90593
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000008810 ! endoplasmic reticulum chaperone BiP
relationship: has_gene_template CGNC:667 ! HSPA5 (chicken)

[Term]
id: PR:000008810
name: endoplasmic reticulum chaperone BiP
def: "An HSPA protein that is a translation product of the human HSPA5 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "BiP" EXACT []
synonym: "GRP78" RELATED Gene-based []
synonym: "HSPA5" EXACT PRO-short-label [PRO:DNx]
synonym: "GRP-78" EXACT []
synonym: "HSP70 family protein 5" EXACT []
synonym: "heat shock 70 kDa protein 5" EXACT []
synonym: "binding-immunoglobulin protein" EXACT []
synonym: "78 kDa glucose-regulated protein" EXACT []
synonym: "heat shock protein family A member 5" EXACT []
synonym: "heat shock protein 70 family protein 5" EXACT []
synonym: "immunoglobulin heavy chain-binding protein" EXACT []
synonym: "endoplasmic reticulum lumenal Ca(2+)-binding protein grp78" EXACT []
is_a: PR:000003426 ! HSPA protein

[Term]
id: PR:Q8T869
name: luminal-binding protein 2 (Dictyostelium discoideum)
def: "An endoplasmic reticulum chaperone BiP that is encoded in the genome of Dictyostelium discoideum." [OMA:Q8T869, PRO:DNx]
comment: Category=organism-gene.
synonym: "bip2" RELATED Gene-based [UniProtKB:Q8T869]
synonym: "Dicty-HSPA5" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0276445" RELATED Gene-based [UniProtKB:Q8T869]
synonym: "BiP 2 (Dictyostelium discoideum)" EXACT [UniProtKB:Q8T869]
xref: UniProtKB:Q8T869
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000008810 ! endoplasmic reticulum chaperone BiP
relationship: has_gene_template dictyBase:DDB_G0276445 ! bip2 (Dictyostelium discoideum)

[Term]
id: PR:000038824
name: endoplasmic reticulum chaperone BiP isoform 1
def: "An endoplasmic reticulum chaperone BiP that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P11021-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "HSPA5/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008810 ! endoplasmic reticulum chaperone BiP

[Term]
id: PR:000047915
name: endoplasmic reticulum chaperone BiP, signal peptide removed form (human)
def: "An endoplasmic reticulum chaperone BiP (human) that has had the signal peptide removed. UniProtKB:P11021, 19-654." [PRO:DNx, Reactome:R-HSA-351315, Reactome:R-HSA-351322, Reactome:R-HSA-387190, Reactome:R-HSA-5252042, Reactome:R-HSA-5252115, Reactome:R-HSA-985498]
comment: Category=organism-modification.
synonym: "PRO_0000013566" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hHSPA5/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P11021, 19-654" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-351315 "PR:000047915 located_in GO:0005789"
xref: Reactome:R-HSA-351322 "PR:000047915 located_in GO:0005576"
xref: Reactome:R-HSA-387190 "PR:000047915 located_in GO:0005788"
xref: Reactome:R-HSA-985498 "PR:000047915 located_in GO:0071556"
xref: Reactome:R-HSA-5252042 "PR:000047915 located_in GO:0005654"
xref: Reactome:R-HSA-5252115 "PR:000047915 located_in GO:0005829"
xref: TDR:1424
intersection_of: PR:P11021 ! endoplasmic reticulum chaperone BiP (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P06761
name: endoplasmic reticulum chaperone BiP (rat)
def: "An endoplasmic reticulum chaperone BiP that is encoded in the genome of rat." [OMA:P06761, PRO:DAN]
comment: Category=organism-gene.
synonym: "Grp78" RELATED Gene-based [UniProtKB:P06761]
synonym: "Hspa5" RELATED Gene-based [UniProtKB:P06761]
synonym: "rHSPA5" EXACT PRO-short-label [PRO:DNx]
synonym: "BiP (rat)" EXACT [UniProtKB:P06761]
synonym: "GRP-78 (rat)" EXACT [UniProtKB:P06761]
synonym: "HSP70 family protein 5 (rat)" EXACT [UniProtKB:P06761]
synonym: "binding-immunoglobulin protein (rat)" EXACT [UniProtKB:P06761]
synonym: "78 kDa glucose-regulated protein (rat)" EXACT [UniProtKB:P06761]
synonym: "heat shock protein family A member 5 (rat)" EXACT [UniProtKB:P06761]
synonym: "steroidogenesis-activator polypeptide (rat)" EXACT [UniProtKB:P06761]
synonym: "heat shock protein 70 family protein 5 (rat)" EXACT [UniProtKB:P06761]
synonym: "immunoglobulin heavy chain-binding protein (rat)" EXACT [UniProtKB:P06761]
xref: UniProtKB:P06761
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000008810 ! endoplasmic reticulum chaperone BiP
relationship: has_gene_template RGD:2843 ! Hspa5 (rat)

[Term]
id: PR:P20029
name: endoplasmic reticulum chaperone BiP (mouse)
def: "An endoplasmic reticulum chaperone BiP that is encoded in the genome of mouse." [OMA:P20029, PRO:DAN]
comment: Category=organism-gene.
synonym: "Grp78" RELATED Gene-based [UniProtKB:P20029]
synonym: "Hspa5" RELATED Gene-based [UniProtKB:P20029]
synonym: "mHSPA5" EXACT PRO-short-label [PRO:DNx]
synonym: "BiP (mouse)" EXACT [UniProtKB:P20029]
synonym: "GRP-78 (mouse)" EXACT [UniProtKB:P20029]
synonym: "HSP70 family protein 5 (mouse)" EXACT [UniProtKB:P20029]
synonym: "binding-immunoglobulin protein (mouse)" EXACT [UniProtKB:P20029]
synonym: "78 kDa glucose-regulated protein (mouse)" EXACT [UniProtKB:P20029]
synonym: "heat shock protein family A member 5 (mouse)" EXACT [UniProtKB:P20029]
synonym: "heat shock protein 70 family protein 5 (mouse)" EXACT [UniProtKB:P20029]
synonym: "immunoglobulin heavy chain-binding protein (mouse)" EXACT [UniProtKB:P20029]
xref: UniProtKB:P20029
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008810 ! endoplasmic reticulum chaperone BiP
relationship: has_gene_template MGI:95835 ! Hspa5 (mouse)

[Term]
id: PR:P11021-1
name: endoplasmic reticulum chaperone BiP isoform 1 (human)
def: "An endoplasmic reticulum chaperone BiP isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hHSPA5/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P11021-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038824 ! endoplasmic reticulum chaperone BiP isoform 1

[Term]
id: PR:000020205
name: endoplasmic reticulum chaperone BiP, signal peptide removed form
def: "An endoplasmic reticulum chaperone BiP that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "HSPA5/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000008810 ! endoplasmic reticulum chaperone BiP
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:P06761-1
name: endoplasmic reticulum chaperone BiP isoform 1 (rat)
def: "An endoplasmic reticulum chaperone BiP isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rHSPA5/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P06761-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000038824 ! endoplasmic reticulum chaperone BiP isoform 1