[Term]
id: PR:P07901-1
name: heat shock protein HSP 90-alpha isoform 1 (mouse)
def: "A heat shock protein HSP 90-alpha isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mHSP90AA1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P07901-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038721 ! heat shock protein HSP 90-alpha isoform 1

[Term]
id: PR:000038721
name: heat shock protein HSP 90-alpha isoform 1
def: "A heat shock protein HSP 90-alpha that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07901-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "HSP90AA1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008799 ! heat shock protein HSP 90-alpha

[Term]
id: PR:P54651
name: heat shock cognate 90 kDa protein (Dictyostelium discoideum)
def: "A heat shock protein HSP 90-alpha that is encoded in the genome of Dictyostelium discoideum." [OMA:P54651, PRO:DNx]
comment: Category=organism-gene.
synonym: "hspD" RELATED Gene-based [UniProtKB:P54651]
synonym: "hsc90" RELATED Gene-based [UniProtKB:P54651]
synonym: "hsp90" RELATED Gene-based [UniProtKB:P54651]
synonym: "DDB_G0267400" RELATED Gene-based [UniProtKB:P54651]
synonym: "Dicty-HSP90AA1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P54651
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000008799 ! heat shock protein HSP 90-alpha
relationship: has_gene_template dictyBase:DDB_G0267400 ! hspD (Dictyostelium discoideum)

[Term]
id: PR:Q76LV2
name: heat shock protein HSP 90-alpha (cow)
def: "A heat shock protein HSP 90-alpha that is encoded in the genome of cow." [OMA:Q76LV2, PRO:DAN]
comment: Category=organism-gene.
synonym: "HSPCA" RELATED Gene-based [UniProtKB:Q76LV2]
synonym: "HSP90A" RELATED Gene-based [UniProtKB:Q76LV2]
synonym: "HSP90AA1" RELATED Gene-based [UniProtKB:Q76LV2]
synonym: "cow-HSP90AA1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q76LV2
intersection_of: only_in_taxon NCBITaxon:9913 ! Bos taurus
intersection_of: PR:000008799 ! heat shock protein HSP 90-alpha
relationship: has_gene_template NCBIGene:281832 ! HSP90AA1 (cow)

[Term]
id: PR:O02705
name: heat shock protein HSP 90-alpha (pig)
def: "A heat shock protein HSP 90-alpha that is encoded in the genome of pig." [OMA:O02705, PRO:DAN]
comment: Category=organism-gene.
synonym: "HSPCA" RELATED Gene-based [UniProtKB:O02705]
synonym: "HSP90A" RELATED Gene-based [UniProtKB:O02705]
synonym: "HSP90AA1" RELATED Gene-based [UniProtKB:O02705]
synonym: "pig-HSP90AA1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O02705
intersection_of: only_in_taxon NCBITaxon:9823 ! Sus scrofa
intersection_of: PR:000008799 ! heat shock protein HSP 90-alpha
relationship: has_gene_template NCBIGene:397028 ! HSP90AA1 (pig)

[Term]
id: PR:Q18688
name: heat shock protein 90 (worm)
def: "A heat shock protein HSP 90-alpha that is encoded in the genome of worm." [OMA:Q18688, PRO:DNx]
comment: Category=organism-gene.
synonym: "daf-21" RELATED Gene-based [UniProtKB:Q18688]
synonym: "C47E8.5" RELATED Gene-based [UniProtKB:Q18688]
synonym: "HSP90AA1 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "abnormal dauer formation protein 21 (worm)" EXACT [UniProtKB:Q18688]
xref: UniProtKB:Q18688
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000008799 ! heat shock protein HSP 90-alpha
relationship: has_gene_template WormBase:WBGene00000915 ! daf-21 (worm)

[Term]
id: PR:P11501
name: heat shock protein HSP 90-alpha (chicken)
def: "A heat shock protein HSP 90-alpha that is encoded in the genome of chicken." [OMA:P11501, PRO:DAN]
comment: Category=organism-gene.
synonym: "HSPCA" RELATED Gene-based [UniProtKB:P11501]
synonym: "HSP90AA1" RELATED Gene-based [UniProtKB:P11501]
synonym: "chick-HSP90AA1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P11501
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000008799 ! heat shock protein HSP 90-alpha
relationship: has_gene_template CGNC:51974 ! HSP90AA1 (chicken)

[Term]
id: PR:P82995-1
name: heat shock protein HSP 90-alpha isoform 1 (rat)
def: "A heat shock protein HSP 90-alpha isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rHSP90AA1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P82995-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000038721 ! heat shock protein HSP 90-alpha isoform 1

[Term]
id: PR:P07900-1
name: heat shock protein HSP 90-alpha isoform 1 (human)
def: "A heat shock protein HSP 90-alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07900-1." [PRO:DNx, UniProtKB:P07900]
comment: Category=organism-sequence. Requested by=PubChem.
synonym: "hHSP90AA1/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "heat shock protein HSP 90-alpha isoform HSP90AA1-1 (human)" EXACT [UniProtKB:P07900]
synonym: "heat shock protein HSP 90-alpha isoform HSP90-alpha 2 (human)" EXACT [UniProtKB:P07900]
xref: UniProtKB:P07900-1
is_a: PR:P07900 ! heat shock protein HSP 90-alpha (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P07900-2
name: heat shock protein HSP 90-alpha isoform h2 (human)
def: "A heat shock protein HSP 90-alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07900-2." [PRO:DNx, UniProtKB:P07900]
comment: Category=organism-sequence.
synonym: "hHSP90AA1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "heat shock protein HSP 90-alpha isoform HSP90AA1-2 (human)" EXACT [UniProtKB:P07900]
xref: UniProtKB:P07900-2
is_a: PR:P07900 ! heat shock protein HSP 90-alpha (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P46598
name: heat shock protein 90 homolog (Candida albicans SC5314)
def: "A heat shock protein HSP 90-alpha that is encoded in the genome of Candida albicans SC5314." [OMA:P46598, PRO:DAN]
comment: Category=organism-gene. Requested by=PubChem. Note: Additional NCBIGenes (GeneIDs) listed in the UniProtKB entry have been reviewed and removed by PRO:DAN.
synonym: "HSP90" RELATED Gene-based [UniProtKB:P46598]
synonym: "CaJ7.0234" RELATED Gene-based [UniProtKB:P46598]
synonym: "CaO19.6515" RELATED Gene-based [UniProtKB:P46598]
synonym: "CaO19.13868" RELATED Gene-based [UniProtKB:P46598]
synonym: "Calb-HSP90AA1" EXACT PRO-short-label [PRO:DNx]
synonym: "CAALFM_C702030WA" RELATED Gene-based [UniProtKB:P46598]
xref: UniProtKB:P46598
intersection_of: only_in_taxon NCBITaxon:237561 ! Candida albicans SC5314
intersection_of: PR:000008799 ! heat shock protein HSP 90-alpha
relationship: has_gene_template NCBIGene:3636951 ! HSP90 (Candida albicans SC5314)

[Term]
id: PR:P07901
name: heat shock protein HSP 90-alpha (mouse)
def: "A heat shock protein HSP 90-alpha that is encoded in the genome of mouse." [OMA:P07901, PRO:DAN]
comment: Category=organism-gene.
synonym: "Hsp86" RELATED Gene-based [UniProtKB:P07901]
synonym: "Hspca" RELATED Gene-based [UniProtKB:P07901]
synonym: "Hsp86-1" RELATED Gene-based [UniProtKB:P07901]
synonym: "Hsp90aa1" RELATED Gene-based [UniProtKB:P07901]
synonym: "mHSP90AA1" EXACT PRO-short-label [PRO:DNx]
synonym: "TSTA (mouse)" BROAD [UniProtKB:P07901]
synonym: "HSP 86 (mouse)" EXACT [UniProtKB:P07901]
synonym: "heat shock 86 kDa (mouse)" EXACT [UniProtKB:P07901]
synonym: "tumor-specific transplantation 86 kDa antigen (mouse)" EXACT [UniProtKB:P07901]
xref: UniProtKB:P07901
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008799 ! heat shock protein HSP 90-alpha
relationship: has_gene_template MGI:96250 ! Hsp90aa1 (mouse)

[Term]
id: PR:000044511
name: heat shock protein HSP 90-alpha, initiator methionine removed non-ubiquitinated 1 (mouse)
def: "A heat shock protein HSP 90-alpha, initiator methionine removed form in mouse that lacks cross-linking to K63-linked polyubiquitin on one or more Lys residues by Hectd1." [PMID:22431752, PRO:KRC, UniProtKB:P07901]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:22431752, for lack of ubiquitination). Evidence=(ECO:0000205, based on UniProtKB:P07901, init met removal).
synonym: "mHSP90AA1 non-ubiquitinated" EXACT []
synonym: "mHSP90AA1/InitMet-/UnUbiq:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000020200 ! heat shock protein HSP 90-alpha, initiator methionine removed form
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P02828
name: heat shock protein 83 (fruit fly)
def: "A heat shock protein HSP 90-alpha that is encoded in the genome of fruit fly." [PRO:DNx]
comment: Category=organism-gene.
synonym: "Hsp82" RELATED Gene-based [UniProtKB:P02828]
synonym: "Hsp83" RELATED Gene-based [UniProtKB:P02828]
synonym: "Hsp90" RELATED Gene-based [UniProtKB:P02828]
synonym: "CG1242" RELATED Gene-based [UniProtKB:P02828]
synonym: "fly-HSP90AA1" EXACT PRO-short-label [PRO:DNx]
synonym: "HSP 82 (fruit fly)" EXACT [UniProtKB:P02828]
xref: UniProtKB:P02828
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000008799 ! heat shock protein HSP 90-alpha
relationship: has_gene_template FlyBase:FBgn0001233 ! Hsp83 (fruit fly)

[Term]
id: PR:P07900
name: heat shock protein HSP 90-alpha (human)
def: "A heat shock protein HSP 90-alpha that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-gene.
synonym: "HSPC1" RELATED Gene-based [UniProtKB:P07900]
synonym: "HSPCA" RELATED Gene-based [UniProtKB:P07900]
synonym: "HSP90A" RELATED Gene-based [UniProtKB:P07900]
synonym: "HSP90AA1" RELATED Gene-based [UniProtKB:P07900]
synonym: "hHSP90AA1" EXACT PRO-short-label [PRO:DNx]
synonym: "HSP86 (human)" EXACT [UniProtKB:P07900]
synonym: "LAP-2 (human)" EXACT [UniProtKB:P07900]
synonym: "HSP 86 (human)" EXACT [UniProtKB:P07900]
synonym: "heat shock 86 kDa (human)" EXACT [UniProtKB:P07900]
synonym: "LPS-associated protein 2 (human)" EXACT [UniProtKB:P07900]
synonym: "renal carcinoma antigen NY-REN-38 (human)" EXACT [UniProtKB:P07900]
synonym: "lipopolysaccharide-associated protein 2 (human)" EXACT [UniProtKB:P07900]
xref: Reactome:R-HSA-9622850 "PR:P07900 located_in GO:0043202"
xref: UniProtKB:P07900
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008799 ! heat shock protein HSP 90-alpha
relationship: has_gene_template HGNC:5253 ! HSP90AA1 (human)

[Term]
id: PR:000020200
name: heat shock protein HSP 90-alpha, initiator methionine removed form
def: "A heat shock protein HSP 90-alpha that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "HSP90AA1/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000008799 ! heat shock protein HSP 90-alpha
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000047909
name: heat shock protein HSP 90-alpha, initiator methionine removed form (human)
def: "A heat shock protein HSP 90-alpha (human) that has had the initiator methionine removed. UniProtKB:P07900, 2-732." [PRO:DNx, Reactome:R-HSA-192864, Reactome:R-HSA-3221912, Reactome:R-HSA-3221946, Reactome:R-HSA-5082401, Reactome:R-HSA-534996]
comment: Category=organism-modification.
synonym: "PRO_0000062911" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hHSP90AA1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P07900, 2-732" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-192864 "PR:000047909 located_in GO:0005829"
xref: Reactome:R-HSA-534996 "PR:000047909 located_in GO:0005886"
xref: Reactome:R-HSA-5082401 "PR:000047909 located_in GO:0005654"
xref: Reactome:R-HSA-3221912 "PR:000047909 located_in GO:0071682"
xref: Reactome:R-HSA-3221946 "PR:000047909 located_in GO:0005576"
xref: Reactome:R-HSA-6801470 "PR:000047909 located_in GO:1904813"
xref: Reactome:R-HSA-6801515 "PR:000047909 located_in GO:0034774"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P07900 ! heat shock protein HSP 90-alpha (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000044494
name: heat shock protein HSP 90-alpha, initiator methionine removed and K63-polyubiquitinated 1 (mouse)
def: "A heat shock protein HSP 90-alpha, initiator methionine removed form in mouse that has been cross-linked on one or more Lys residues to K63-linked polyubiquitin by Hectd1." [PMID:22431752, PRO:DAN, PRO:KRC]
comment: Category=organism-modification. UbLigase=("HECTD1"; PR:Q69ZR2). Evidence=(ECO:0000006, based on PMID:22431752, for ubiquitination). Evidence=(ECO:0000205, based on UniProtKB:P07901, init met removal).
synonym: "mHSP90AA1 K63-Ub" EXACT []
synonym: "mHSP90AA1 ubiquitinated" EXACT []
synonym: "mHSP90AA1/InitMet-/K63polyUbiq:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000020200 ! heat shock protein HSP 90-alpha, initiator methionine removed form
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus
relationship: has_part PR:000044772 ! K63-polyubiquitinylated lysine

[Term]
id: PR:P82995
name: heat shock protein HSP 90-alpha (rat)
def: "A heat shock protein HSP 90-alpha that is encoded in the genome of rat." [OMA:P82995, PRO:DAN]
comment: Category=organism-gene.
synonym: "Hsp86" RELATED Gene-based [UniProtKB:P82995]
synonym: "Hspca" RELATED Gene-based [UniProtKB:P82995]
synonym: "Hsp90aa1" RELATED Gene-based [UniProtKB:P82995]
synonym: "rHSP90AA1" EXACT PRO-short-label [PRO:DNx]
synonym: "HSP 86 (rat)" EXACT [UniProtKB:P82995]
synonym: "heat shock 86 kDa (rat)" EXACT [UniProtKB:P82995]
xref: UniProtKB:P82995
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000008799 ! heat shock protein HSP 90-alpha
relationship: has_gene_template RGD:631409 ! Hsp90aa1 (rat)

[Term]
id: PR:000008799
name: heat shock protein HSP 90-alpha
def: "An HSPC protein that is a translation product of the human HSP90AA1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TSTA" BROAD [PRO:DNx]
synonym: "HSP86" EXACT []
synonym: "HSPC1" RELATED Gene-based []
synonym: "HSPCA" RELATED Gene-based []
synonym: "HSP 86" EXACT []
synonym: "HSP90A" RELATED Gene-based []
synonym: "Hsp86-1" RELATED Gene-based []
synonym: "HSP90AA1" EXACT PRO-short-label [PRO:DNx]
synonym: "heat shock 86 kDa" EXACT []
synonym: "renal carcinoma antigen NY-REN-38" EXACT []
synonym: "tumor-specific transplantation 86 kDa antigen" EXACT []
xref: IUPHARobj:2905
is_a: PR:000025350 ! HSPC protein