[Term]
id: PR:O70503
name: very-long-chain 3-oxoacyl-CoA reductase (mouse)
def: "A very-long-chain 3-oxoacyl-CoA reductase that is encoded in the genome of mouse." [OMA:O70503, PRO:DNx]
comment: Category=organism-gene.
synonym: "Kik1" RELATED Gene-based [UniProtKB:O70503]
synonym: "Hsd17b12" RELATED Gene-based [UniProtKB:O70503]
synonym: "mHSD17B12" EXACT PRO-short-label [PRO:DNx]
synonym: "KAR (mouse)" EXACT [UniProtKB:O70503]
synonym: "KIK-I (mouse)" EXACT [UniProtKB:O70503]
synonym: "17-beta-HSD 12 (mouse)" EXACT [UniProtKB:O70503]
synonym: "3-ketoacyl-CoA reductase (mouse)" EXACT [UniProtKB:O70503]
synonym: "estradiol 17-beta-dehydrogenase 12 (mouse)" EXACT [UniProtKB:O70503]
synonym: "17-beta-hydroxysteroid dehydrogenase 12 (mouse)" EXACT [UniProtKB:O70503]
xref: UniProtKB:O70503
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008776 ! very-long-chain 3-oxoacyl-CoA reductase
relationship: has_gene_template MGI:1926967 ! Hsd17b12 (mouse)

[Term]
id: PR:O70503-1
name: very-long-chain 3-oxoacyl-CoA reductase isoform 1 (mouse)
def: "A very-long-chain 3-oxoacyl-CoA reductase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mHSD17B12/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O70503-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040886 ! very-long-chain 3-oxoacyl-CoA reductase isoform 1

[Term]
id: PR:O70503-2
name: very-long-chain 3-oxoacyl-CoA reductase isoform m2 (mouse)
def: "A very-long-chain 3-oxoacyl-CoA reductase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O70503-2." [PRO:DNx, UniProtKB:O70503]
comment: Category=organism-sequence.
synonym: "mHSD17B12/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O70503-2
is_a: PR:O70503 ! very-long-chain 3-oxoacyl-CoA reductase (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q53GQ0-1
name: very-long-chain 3-oxoacyl-CoA reductase isoform 1 (human)
def: "A very-long-chain 3-oxoacyl-CoA reductase isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hHSD17B12/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q53GQ0-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040886 ! very-long-chain 3-oxoacyl-CoA reductase isoform 1

[Term]
id: PR:Q6P7R8
name: very-long-chain 3-oxoacyl-CoA reductase (rat)
def: "A very-long-chain 3-oxoacyl-CoA reductase that is encoded in the genome of rat." [OMA:Q6P7R8, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hsd17b12" RELATED Gene-based [UniProtKB:Q6P7R8]
synonym: "KAR (rat)" EXACT [UniProtKB:Q6P7R8]
synonym: "rHSD17B12" EXACT PRO-short-label [PRO:DNx]
synonym: "17-beta-HSD 12 (rat)" EXACT [UniProtKB:Q6P7R8]
synonym: "3-ketoacyl-CoA reductase (rat)" EXACT [UniProtKB:Q6P7R8]
synonym: "estradiol 17-beta-dehydrogenase 12 (rat)" EXACT [UniProtKB:Q6P7R8]
synonym: "17-beta-hydroxysteroid dehydrogenase 12 (rat)" EXACT [UniProtKB:Q6P7R8]
xref: UniProtKB:Q6P7R8
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000008776 ! very-long-chain 3-oxoacyl-CoA reductase
relationship: has_gene_template RGD:708367 ! Hsd17b12 (rat)

[Term]
id: PR:Q6P7R8-1
name: very-long-chain 3-oxoacyl-CoA reductase isoform 1 (rat)
def: "A very-long-chain 3-oxoacyl-CoA reductase isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rHSD17B12/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q6P7R8-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000040886 ! very-long-chain 3-oxoacyl-CoA reductase isoform 1

[Term]
id: PR:000008776
name: very-long-chain 3-oxoacyl-CoA reductase
def: "A protein that is a translation product of the human HSD17B12 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "KAR" EXACT []
synonym: "Kik1" RELATED Gene-based []
synonym: "KIK-I" EXACT []
synonym: "SDR12C1" RELATED Gene-based []
synonym: "HSD17B12" EXACT PRO-short-label [PRO:DNx]
synonym: "17-beta-HSD 12" EXACT []
synonym: "3-ketoacyl-CoA reductase" EXACT []
synonym: "estradiol 17-beta-dehydrogenase 12" EXACT []
synonym: "17-beta-hydroxysteroid dehydrogenase 12" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000040886
name: very-long-chain 3-oxoacyl-CoA reductase isoform 1
def: "A very-long-chain 3-oxoacyl-CoA reductase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q53GQ0-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "HSD17B12/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008776 ! very-long-chain 3-oxoacyl-CoA reductase

[Term]
id: PR:Q53GQ0
name: very-long-chain 3-oxoacyl-CoA reductase (human)
def: "A very-long-chain 3-oxoacyl-CoA reductase that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q53GQ0]
comment: Category=organism-gene.
synonym: "SDR12C1" RELATED Gene-based [UniProtKB:Q53GQ0]
synonym: "HSD17B12" RELATED Gene-based [UniProtKB:Q53GQ0]
synonym: "hHSD17B12" EXACT PRO-short-label [PRO:DNx]
synonym: "KAR (human)" EXACT [UniProtKB:Q53GQ0]
synonym: "17-beta-HSD 12 (human)" EXACT [UniProtKB:Q53GQ0]
synonym: "3-ketoacyl-CoA reductase (human)" EXACT [UniProtKB:Q53GQ0]
synonym: "estradiol 17-beta-dehydrogenase 12 (human)" EXACT [PRO:DNx]
synonym: "17-beta-hydroxysteroid dehydrogenase 12 (human)" EXACT [UniProtKB:Q53GQ0]
synonym: "short chain dehydrogenase/reductase family 12C member 1 (human)" EXACT [UniProtKB:Q53GQ0]
xref: Reactome:R-HSA-548766 "PR:Q53GQ0 located_in GO:0005789"
xref: UniProtKB:Q53GQ0
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008776 ! very-long-chain 3-oxoacyl-CoA reductase
relationship: has_gene_template HGNC:18646 ! HSD17B12 (human)

[Term]
id: PR:Q53GQ0-2
name: very-long-chain 3-oxoacyl-CoA reductase isoform h2 (human)
def: "A very-long-chain 3-oxoacyl-CoA reductase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q53GQ0-2." [PRO:DNx, UniProtKB:Q53GQ0]
comment: Category=organism-sequence.
synonym: "hHSD17B12/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q53GQ0-2
is_a: PR:Q53GQ0 ! very-long-chain 3-oxoacyl-CoA reductase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens