[Term] id: PR:P56524 name: histone deacetylase 4 (human) def: "A histone deacetylase 4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P56524] comment: Category=organism-gene. Requested by=PubChem. synonym: "HDAC4" RELATED Gene-based [UniProtKB:P56524] synonym: "hHDAC4" EXACT PRO-short-label [PRO:DNx] synonym: "KIAA0288" RELATED Gene-based [UniProtKB:P56524] synonym: "HD4 (human)" EXACT [UniProtKB:P56524] xref: Reactome:R-HSA-351581 "PR:P56524 located_in GO:0005654" xref: UniProtKB:P56524 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000008483 ! histone deacetylase 4 relationship: has_gene_template HGNC:14063 ! HDAC4 (human) [Term] id: PR:P56524-1 name: histone deacetylase 4 isoform 1 (human) def: "A histone deacetylase 4 isoform 1 that is encoded in the genome of human." [PRO:ALI] comment: Category=organism-sequence. synonym: "hHDAC4/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P56524-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028999 ! histone deacetylase 4 isoform 1 [Term] id: PR:P56524-2 name: histone deacetylase 4 isoform h2 (human) def: "A histone deacetylase 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56524-2." [PRO:DNx, UniProtKB:P56524] comment: Category=organism-sequence. synonym: "hHDAC4/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P56524-2 is_a: PR:P56524 ! histone deacetylase 4 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q6NZM9 name: histone deacetylase 4 (mouse) def: "A histone deacetylase 4 that is encoded in the genome of mouse." [OMA:Q6NZM9, PRO:DNx] comment: Category=organism-gene. synonym: "Hdac4" RELATED Gene-based [UniProtKB:Q6NZM9] synonym: "mHDAC4" EXACT PRO-short-label [PRO:DNx] synonym: "HD4 (mouse)" EXACT [UniProtKB:Q6NZM9] xref: UniProtKB:Q6NZM9 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000008483 ! histone deacetylase 4 relationship: has_gene_template MGI:3036234 ! Hdac4 (mouse) [Term] id: PR:000028999 name: histone deacetylase 4 isoform 1 def: "A histone deacetylase 4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56524-1 or a 1:1 ortholog thereof." [PMID:17179159, PRO:ALI] comment: Category=sequence. synonym: "HDAC4/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000008483 ! histone deacetylase 4 [Term] id: PR:000029001 name: histone deacetylase 4 isoform 1 phosphorylated 1 def: "A histone deacetylase 4 isoform 1 that has been phosphorylated on Ser residues as a result of the activation of the CAMK2D isoform delta 3 (also known as delta B) in cardiac cells. Example: UniProtKB:P56524-1, Ser-210/Ser-246, MOD:00046." [PMID:17179159, PRO:ALI] comment: Category=modification. synonym: "HDAC4/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "HDAC4 phosphorylated" RELATED [] is_a: PR:000028999 ! histone deacetylase 4 isoform 1 relationship: has_part MOD:00046 ! O-phospho-L-serine [Term] id: PR:000029002 name: histone deacetylase 4 isoform 1 phosphorylated 1 (human) def: "A histone deacetylase 4 isoform 1 phosphorylated 1 in human. UniProtKB:P56524-1, Ser-210/Ser-246, MOD:00046." [PMID:17179159, PRO:ALI] comment: Category=organism-modification. Kinase=("CAMK2D"; PR:Q13557-3). synonym: "hHDAC4/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "HDAC4 phosphorylated (human)" RELATED [] synonym: "UniProtKB:P56524-1, Ser-210/Ser-246, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000029001 ! histone deacetylase 4 isoform 1 phosphorylated 1 relationship: has_part MOD:00046 ! O-phospho-L-serine [Term] id: PR:Q6NZM9-2 name: histone deacetylase 4 isoform m2 (mouse) def: "A histone deacetylase 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6NZM9-2." [PRO:DNx, UniProtKB:Q6NZM9] comment: Category=organism-sequence. synonym: "mHDAC4/iso:m2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q6NZM9-2 is_a: PR:Q6NZM9 ! histone deacetylase 4 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q6NZM9-1 name: histone deacetylase 4 isoform m1 (mouse) def: "A histone deacetylase 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6NZM9-1." [PRO:DNx, UniProtKB:Q6NZM9] comment: Category=organism-sequence. synonym: "mHDAC4/iso:m1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q6NZM9-1 is_a: PR:Q6NZM9 ! histone deacetylase 4 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P83038 name: histone deacetylase 4 (chicken) def: "A histone deacetylase 4 that is encoded in the genome of chicken." [OMA:P83038, PANTHER:PTHR10625:SF21, PRO:DNx] comment: Category=organism-gene. synonym: "HDAC4" RELATED Gene-based [UniProtKB:P83038] synonym: "chick-HDAC4" EXACT PRO-short-label [PRO:DNx] synonym: "HD4 (chicken)" EXACT [UniProtKB:P83038] xref: UniProtKB:P83038 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000008483 ! histone deacetylase 4 relationship: has_gene_template NCBIGene:374207 ! HDAC4 (chicken) [Term] id: PR:Q99P99 name: histone deacetylase 4 (rat) def: "A histone deacetylase 4 that is encoded in the genome of rat." [OMA:Q99P99, PANTHER:PTHR10625:SF21, PRO:DNx] comment: Category=organism-gene. synonym: "Hdac4" RELATED Gene-based [UniProtKB:Q99P99] synonym: "rHDAC4" EXACT PRO-short-label [PRO:DNx] synonym: "HD4 (rat)" EXACT [UniProtKB:Q99P99] xref: UniProtKB:Q99P99 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000008483 ! histone deacetylase 4 relationship: has_gene_template RGD:619979 ! Hdac4 (rat) [Term] id: PR:000008483 name: histone deacetylase 4 def: "A protein that is a translation product of the human HDAC4 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "HD4" EXACT [] synonym: "HDAC4" EXACT PRO-short-label [PRO:DNx] synonym: "KIAA0288" RELATED Gene-based [] xref: IUPHARobj:2659 is_a: PR:000000001 ! protein