[Term] id: PR:000047676 name: histidine--tRNA ligase, cytoplasmic, initiator methionine removed form (human) def: "A histidine--tRNA ligase, cytoplasmic (human) that has had the initiator methionine removed. UniProtKB:P12081, 2-509." [PRO:DNx, Reactome:R-HSA-379554] comment: Category=organism-modification. synonym: "PRO_0000136332" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hHARS/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P12081, 2-509" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-379554 "PR:000047676 located_in GO:0005829" intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:P12081 ! histidine--tRNA ligase, cytoplasmic (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000008448 name: histidyl-tRNA synthetase, cytoplasmic def: "A protein that is a translation product of the human HARS1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "HRS" RELATED Gene-based [] synonym: "HARS" RELATED Gene-based [] synonym: "HARS1" EXACT PRO-short-label [PRO:DNx] synonym: "HisRS" BROAD [PRO:DNx] synonym: "histidine--tRNA ligase" BROAD [PRO:DNx] is_a: PR:000000001 ! protein [Term] id: PR:P12081 name: histidine--tRNA ligase, cytoplasmic (human) def: "A histidyl-tRNA synthetase, cytoplasmic that is encoded in the genome of human." [PRO:DNx, UniProtKB:P12081] comment: Category=organism-gene. synonym: "HRS" RELATED Gene-based [UniProtKB:P12081] synonym: "HARS" RELATED Gene-based [UniProtKB:P12081] synonym: "HARS1" RELATED Gene-based [UniProtKB:P12081] synonym: "hHARS1" EXACT PRO-short-label [PRO:DNx] synonym: "HisRS (human)" BROAD [PRO:DAN] synonym: "histidine--tRNA ligase (human)" BROAD [PRO:DAN] synonym: "histidyl-tRNA synthetase (human)" BROAD [PRO:DAN] synonym: "histidyl-tRNA synthetase, cytoplasmic (human)" EXACT [PRO:DAN] xref: UniProtKB:P12081 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000008448 ! histidyl-tRNA synthetase, cytoplasmic relationship: has_gene_template HGNC:4816 ! HARS1 (human) [Term] id: PR:P12081-4 name: histidine--tRNA ligase, cytoplasmic isoform h4 (human) def: "A histidine--tRNA ligase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12081-4." [PRO:DNx, UniProtKB:P12081] comment: Category=organism-sequence. synonym: "hHARS1/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P12081-4 is_a: PR:P12081 ! histidine--tRNA ligase, cytoplasmic (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P12081-2 name: histidine--tRNA ligase, cytoplasmic isoform h2 (human) def: "A histidine--tRNA ligase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12081-2." [PRO:DNx, UniProtKB:P12081] comment: Category=organism-sequence. synonym: "hHARS1/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P12081-2 is_a: PR:P12081 ! histidine--tRNA ligase, cytoplasmic (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P12081-3 name: histidine--tRNA ligase, cytoplasmic isoform h3 (human) def: "A histidine--tRNA ligase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12081-3." [PRO:DNx, UniProtKB:P12081] comment: Category=organism-sequence. synonym: "hHARS1/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P12081-3 is_a: PR:P12081 ! histidine--tRNA ligase, cytoplasmic (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P12081-1 name: histidine--tRNA ligase, cytoplasmic isoform 1 (human) def: "A histidyl-tRNA synthetase, cytoplasmic isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hHARS/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P12081-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000038860 ! histidyl-tRNA synthetase, cytoplasmic isoform 1