[Term]
id: PR:P52785-1
name: guanylyl cyclase GC-E isoform 1 (mouse)
def: "A retinal guanylyl cyclase 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mGUCY2D/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P52785-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039711 ! retinal guanylyl cyclase 1 isoform 1

[Term]
id: PR:000039711
name: retinal guanylyl cyclase 1 isoform 1
def: "A retinal guanylyl cyclase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P52785-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "GUCY2D/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000008353 ! retinal guanylyl cyclase 1

[Term]
id: PR:000008353
name: retinal guanylyl cyclase 1
def: "A protein that is a translation product of the human GUCY2D gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CORD6" RELATED Gene-based []
synonym: "GUC2D" RELATED Gene-based []
synonym: "Guc2e" RELATED Gene-based []
synonym: "RETGC" RELATED Gene-based []
synonym: "GUC1A4" RELATED Gene-based []
synonym: "GUCY2D" EXACT PRO-short-label [PRO:DNx]
synonym: "Gucy2e" RELATED Gene-based []
synonym: "RETGC1" RELATED Gene-based []
synonym: "ROS-GC" EXACT []
synonym: "RETGC-1" EXACT []
synonym: "guanylate cyclase 2E" EXACT []
synonym: "guanylyl cyclase GC-E" EXACT []
synonym: "guanylate cyclase 2D, retinal" EXACT []
synonym: "rod outer segment membrane guanylate cyclase" EXACT []
xref: IUPHARobj:2031
is_a: PR:000000001 ! protein

[Term]
id: PR:P52785
name: retinal guanylyl cyclase 1 (mouse)
def: "A retinal guanylyl cyclase 1 that is encoded in the genome of mouse." [OMA:P52785, PRO:DNx]
comment: Category=organism-gene.
synonym: "Guc2e" RELATED Gene-based [UniProtKB:P52785]
synonym: "Gucy2e" RELATED Gene-based [UniProtKB:P52785]
synonym: "mGUCY2D" EXACT PRO-short-label [PRO:DNx]
synonym: "guanylate cyclase 2E (mouse)" EXACT [UniProtKB:P52785]
synonym: "guanylyl cyclase GC-E (mouse)" EXACT [UniProtKB:P52785]
xref: UniProtKB:P52785
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000008353 ! retinal guanylyl cyclase 1
relationship: has_gene_template MGI:105123 ! Gucy2e (mouse)

[Term]
id: PR:P51840
name: retinal guanylyl cyclase 1 (rat)
def: "A retinal guanylyl cyclase 1 that is encoded in the genome of rat." [OMA:P51840, PRO:DNx]
comment: Category=organism-gene. Note: In mouse this gene is called Gucy2e.
synonym: "Guc2e" RELATED Gene-based [UniProtKB:P51840]
synonym: "Gucy2d" RELATED Gene-based [UniProtKB:P51840]
synonym: "Gucy2e" RELATED Gene-based [UniProtKB:P51840]
synonym: "rGucy2e" EXACT PRO-short-label [PRO:DNx]
synonym: "RETGC-1 (rat)" EXACT [UniProtKB:P51840]
synonym: "guanylate cyclase 2E (rat)" EXACT [UniProtKB:P51840]
synonym: "guanylyl cyclase GC-E (rat)" EXACT [UniProtKB:P51840]
xref: UniProtKB:P51840
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000008353 ! retinal guanylyl cyclase 1
relationship: has_gene_template RGD:620438 ! Gucy2d (rat)

[Term]
id: PR:Q02846
name: retinal guanylyl cyclase 1 (human)
def: "A retinal guanylyl cyclase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q02846]
comment: Category=organism-gene.
synonym: "CORD6" RELATED Gene-based [UniProtKB:Q02846]
synonym: "GUC2D" RELATED Gene-based [UniProtKB:Q02846]
synonym: "RETGC" RELATED Gene-based [UniProtKB:Q02846]
synonym: "GUC1A4" RELATED Gene-based [UniProtKB:Q02846]
synonym: "GUCY2D" RELATED Gene-based [UniProtKB:Q02846]
synonym: "RETGC1" RELATED Gene-based [UniProtKB:Q02846]
synonym: "hGUCY2D" EXACT PRO-short-label [PRO:DNx]
synonym: "CG-E (human)" EXACT [UniProtKB:Q02846]
synonym: "ROS-GC (human)" EXACT [UniProtKB:Q02846]
synonym: "RETGC-1 (human)" EXACT [UniProtKB:Q02846]
synonym: "guanylate cyclase 2D, retinal (human)" EXACT [UniProtKB:Q02846]
synonym: "rod outer segment membrane guanylate cyclase (human)" EXACT [UniProtKB:Q02846]
xref: DTO:03100167
xref: UniProtKB:Q02846
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008353 ! retinal guanylyl cyclase 1
relationship: has_gene_template HGNC:4689 ! GUCY2D (human)

[Term]
id: PR:000047657
name: retinal guanylyl cyclase 1, signal peptide removed form (human)
def: "A retinal guanylyl cyclase 1 (human) that has had the signal peptide removed. UniProtKB:Q02846, 52-1103." [PRO:DNx, Reactome:R-HSA-74914]
comment: Category=organism-modification.
synonym: "PRO_0000012381" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hGUCY2D/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q02846, 52-1103" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-74914 "PR:000047657 located_in GO:0097381"
intersection_of: PR:Q02846 ! retinal guanylyl cyclase 1 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens