[Term] id: PR:Q9EQX0-1 name: appetite-regulating hormone isoform 1 (mouse) def: "An appetite-regulating hormone isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mGHRL/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "appetite-regulating hormone isoform Ghrelin (mouse)" EXACT [UniProtKB:Q9EQX0] xref: UniProtKB:Q9EQX0-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000043841 ! appetite-regulating hormone isoform 1 [Term] id: PR:Q9EQX0-2 name: appetite-regulating hormone isoform 2 (mouse) def: "An appetite-regulating hormone isoform 2 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mGHRL/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "appetite-regulating hormone isoform des-Gln14-ghrelin (mouse)" EXACT [UniProtKB:Q9EQX0] xref: UniProtKB:Q9EQX0-2 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000043842 ! appetite-regulating hormone isoform 2 [Term] id: PR:Q9UBU3-4 name: appetite-regulating hormone isoform h4 (human) def: "An appetite-regulating hormone (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBU3-4." [PRO:DNx, UniProtKB:Q9UBU3] comment: Category=organism-sequence. synonym: "hGHRL/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9UBU3-4 is_a: PR:Q9UBU3 ! appetite-regulating hormone (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9UBU3-3 name: appetite-regulating hormone isoform h3 (human) def: "An appetite-regulating hormone (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBU3-3." [PRO:DNx, UniProtKB:Q9UBU3] comment: Category=organism-sequence. synonym: "hGHRL/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9UBU3-3 is_a: PR:Q9UBU3 ! appetite-regulating hormone (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9UBU3-2 name: appetite-regulating hormone isoform 2 (human) def: "An appetite-regulating hormone isoform 2 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hGHRL/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "appetite-regulating hormone isoform des-Gln14-ghrelin (human)" EXACT [UniProtKB:Q9UBU3] xref: UniProtKB:Q9UBU3-2 xref: Reactome:R-HSA-422044 "PR:Q9UBU3-2 located_in GO:0005788" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000043842 ! appetite-regulating hormone isoform 2 [Term] id: PR:Q9UBU3-1 name: appetite-regulating hormone isoform 1 (human) def: "An appetite-regulating hormone isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hGHRL/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "appetite-regulating hormone isoform Ghrelin (human)" EXACT [UniProtKB:Q9UBU3] xref: UniProtKB:Q9UBU3-1 xref: Reactome:R-HSA-422027 "PR:Q9UBU3-1 located_in GO:0005788" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000043841 ! appetite-regulating hormone isoform 1 [Term] id: PR:Q9UBU3-6 name: appetite-regulating hormone isoform h6 (human) def: "An appetite-regulating hormone (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBU3-6." [PRO:DNx, UniProtKB:Q9UBU3] comment: Category=organism-sequence. synonym: "hGHRL/iso:h6" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9UBU3-6 is_a: PR:Q9UBU3 ! appetite-regulating hormone (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9UBU3-5 name: appetite-regulating hormone isoform h5 (human) def: "An appetite-regulating hormone (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBU3-5." [PRO:DNx, UniProtKB:Q9UBU3] comment: Category=organism-sequence. synonym: "hGHRL/iso:h5" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9UBU3-5 is_a: PR:Q9UBU3 ! appetite-regulating hormone (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000043841 name: appetite-regulating hormone isoform 1 def: "An appetite-regulating hormone that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBU3-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "GHRL/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000007973 ! appetite-regulating hormone [Term] id: PR:000044485 name: appetite-regulating hormone isoform 1 cleaved and non-octanoylated 1 def: "An appetite-regulating hormone isoform 1 cleaved 1 that lacks the O-octanoylation on the third Ser of the mature form. Example: UniProtKB:Q9EQX0-1, 24-51, Ser-26, PR:000026291." [PRO:CNA, PRO:DAN] comment: Category=modification. synonym: "GHRL/iso:1/ClvUnOOct:1" EXACT PRO-short-label [PRO:DAN] is_a: PR:000044479 ! appetite-regulating hormone isoform 1 cleaved 1 [Term] id: PR:000044484 name: appetite-regulating hormone isoform 1 cleaved and O-octanoylated 1 (human) def: "An appetite-regulating hormone isoform 1 cleaved and O-octanoylated 1 in human. UniProtKB:Q9UBU3-1, 24-51, Ser-26, MOD:00295." [PMID:10604470, PRO:CNA] comment: Category=organism-modification. synonym: "hGHRL/iso:1/ClvOOct:1" EXACT PRO-short-label [PRO:DAN] synonym: "ghrelin-28 active form (human)" EXACT [] synonym: "UniProtKB:Q9UBU3-1, 24-51, Ser-26, MOD:00295" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000044482 ! appetite-regulating hormone isoform 1 cleaved and O-octanoylated 1 relationship: has_part MOD:00295 ! O-octanoyl-L-serine [Term] id: PR:Q9QYH7-2 name: appetite-regulating hormone isoform 2 (rat) def: "An appetite-regulating hormone isoform 2 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rGHRL/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "appetite-regulating hormone isoform des-Gln14-ghrelin (rat)" EXACT [UniProtKB:Q9QYH7] xref: UniProtKB:Q9QYH7-2 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000043842 ! appetite-regulating hormone isoform 2 [Term] id: PR:Q9QYH7-1 name: appetite-regulating hormone isoform 1 (rat) def: "An appetite-regulating hormone isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rGHRL/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "appetite-regulating hormone isoform Ghrelin (rat)" EXACT [UniProtKB:Q9QYH7] xref: UniProtKB:Q9QYH7-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000043841 ! appetite-regulating hormone isoform 1 [Term] id: PR:000043842 name: appetite-regulating hormone isoform 2 def: "An appetite-regulating hormone that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBU3-2 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "GHRL/iso:2" EXACT PRO-short-label [PRO:DNx] is_a: PR:000007973 ! appetite-regulating hormone [Term] id: PR:000044480 name: appetite-regulating hormone isoform 1 cleaved 1 (mouse) def: "An appetite-regulating hormone isoform 1 cleaved 1 in mouse. UniProtKB:Q9EQX0-1, 24-51." [PMID:11306336, PMID:15591499, PRO:HJD] comment: Category=organism-modification. synonym: "PRO_0000019205" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "ghrelin (mouse)" EXACT [PRO:DAN] synonym: "mGHRL/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx] synonym: "ghrelin-28 (mouse)" EXACT [PRO:DAN] synonym: "UniProtKB:Q9EQX0-1, 24-51" EXACT PRO-proteoform-std [PRO:DNx] synonym: "ghrelin mature form (mouse)" EXACT [] intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000044479 ! appetite-regulating hormone isoform 1 cleaved 1 [Term] id: PR:000044486 name: appetite-regulating hormone isoform 1 cleaved and non-octanoylated 1 (mouse) def: "An appetite-regulating hormone isoform 1 cleaved and non-octanoylated 1 in mouse. UniProtKB:Q9EQX0-1, 24-51, Ser-26, PR:000026291." [PMID:15591499, PRO:HJD] comment: Category=organism-modification. synonym: "mGHRL/iso:1/ClvUnOOct:1" EXACT PRO-short-label [PRO:DAN] synonym: "UniProtKB:Q9EQX0-1, 24-51, Ser-26, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000044485 ! appetite-regulating hormone isoform 1 cleaved and non-octanoylated 1 [Term] id: PR:000044482 name: appetite-regulating hormone isoform 1 cleaved and O-octanoylated 1 def: "An appetite-regulating hormone isoform 1 cleaved 1 that has been post-translationally modified to include an O-octanoyl-serine at the third Ser of the mature form. Example: UniProtKB:Q9UBU3-1, 24-51, Ser-26, MOD:00295." [PRO:CNA] comment: Category=modification. synonym: "ghrelin active form" EXACT [] synonym: "GHRL/iso:1/ClvOOct:1" EXACT PRO-short-label [PRO:DAN] is_a: PR:000044479 ! appetite-regulating hormone isoform 1 cleaved 1 relationship: has_part MOD:00295 ! O-octanoyl-L-serine [Term] id: PR:000044483 name: appetite-regulating hormone isoform 1 cleaved and O-octanoylated 1 (mouse) def: "An appetite-regulating hormone isoform 1 cleaved and O-octanoylated 1 in mouse. UniProtKB:Q9EQX0-1, 24-51, Ser-26, MOD:00295." [PMID:15591499, PRO:HJD] comment: Category=organism-modification. Enzyme=("MBOAT4"; PR:P0C7A3). synonym: "mGHRL/iso:1/ClvOOct:1" EXACT PRO-short-label [PRO:DAN] synonym: "ghrelin active form (mouse)" EXACT [] synonym: "UniProtKB:Q9EQX0-1, 24-51, Ser-26, MOD:00295" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000044482 ! appetite-regulating hormone isoform 1 cleaved and O-octanoylated 1 relationship: has_part MOD:00295 ! O-octanoyl-L-serine [Term] id: PR:Q9EQX0 name: appetite-regulating hormone (mouse) def: "An appetite-regulating hormone that is encoded in the genome of mouse." [OMA:Q9EQX0, PRO:DNx] comment: Category=organism-gene. synonym: "Ghrl" RELATED Gene-based [UniProtKB:Q9EQX0] synonym: "Mtlrp" RELATED Gene-based [UniProtKB:Q9EQX0] synonym: "mGHRL" EXACT PRO-short-label [PRO:DNx] synonym: "protein M46 (mouse)" EXACT [UniProtKB:Q9EQX0] synonym: "motilin-related peptide (mouse)" EXACT [UniProtKB:Q9EQX0] synonym: "growth hormone secretagogue (mouse)" EXACT [UniProtKB:Q9EQX0] synonym: "growth hormone-releasing peptide (mouse)" EXACT [UniProtKB:Q9EQX0] xref: UniProtKB:Q9EQX0 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000007973 ! appetite-regulating hormone relationship: has_gene_template MGI:1930008 ! Ghrl (mouse) [Term] id: PR:Q9QYH7 name: appetite-regulating hormone (rat) def: "An appetite-regulating hormone that is encoded in the genome of rat." [OMA:Q9QYH7, PANTHER:PTHR14122:SF0, PRO:DNx] comment: Category=organism-gene. synonym: "Ghrl" RELATED Gene-based [UniProtKB:Q9QYH7] synonym: "rGHRL" EXACT PRO-short-label [PRO:DNx] synonym: "motilin-related peptide (rat)" EXACT [UniProtKB:Q9QYH7] synonym: "growth hormone secretagogue (rat)" EXACT [UniProtKB:Q9QYH7] synonym: "growth hormone-releasing peptide (rat)" EXACT [UniProtKB:Q9QYH7] xref: UniProtKB:Q9QYH7 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000007973 ! appetite-regulating hormone relationship: has_gene_template RGD:632283 ! Ghrl (rat) [Term] id: PR:000019998 name: appetite-regulating hormone, signal peptide removed form def: "An appetite-regulating hormone that has had the signal peptide removed." [PRO:DNx] comment: Category=modification. synonym: "GHRL/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000007973 ! appetite-regulating hormone intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000019999 name: appetite-regulating hormone proteolytic cleavage product def: "An appetite-regulating hormone that has been processed by proteolytic cleavage." [PRO:DNx] comment: Category=modification. synonym: "GHRL/ClvPrd" EXACT PRO-short-label [PRO:DNx] intersection_of: output_of GO:0016485 ! protein processing intersection_of: PR:000007973 ! appetite-regulating hormone [Term] id: PR:000044481 name: appetite-regulating hormone isoform 1 cleaved 1 (human) def: "An appetite-regulating hormone isoform 1 cleaved 1 in human. UniProtKB:Q9UBU3-1, 24-51." [PMID:10604470, PRO:CNA] comment: Category=organism-modification. synonym: "PRO_0000019202" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hGHRL/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx] synonym: "ghrelin-28 (human)" EXACT [] synonym: "UniProtKB:Q9UBU3-1, 24-51" EXACT PRO-proteoform-std [PRO:DNx] synonym: "ghrelin mature form (human)" EXACT [PRO:DAN] xref: Reactome:R-HSA-422043 "PR:000044481 located_in GO:0005576" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000044479 ! appetite-regulating hormone isoform 1 cleaved 1 [Term] id: PR:000044479 name: appetite-regulating hormone isoform 1 cleaved 1 def: "An appetite-regulating hormone isoform 1 that has had the signal peptide and propeptide removed. Example: UniProtKB:Q9UBU3-1, 24-51." [PRO:CNA] comment: Category=modification. synonym: "ghrelin-28" EXACT [PRO:DAN] synonym: "GHRL/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000043841 ! appetite-regulating hormone isoform 1 intersection_of: lacks_part SO:0000418 ! signal_peptide intersection_of: lacks_part SO:0001062 ! propeptide [Term] id: PR:000007973 name: appetite-regulating hormone def: "A protein that is a translation product of the human GHRL gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "GHRL" EXACT PRO-short-label [PRO:DNx] synonym: "MTLRP" RELATED Gene-based [] synonym: "protein M46" EXACT [] synonym: "UNQ524/PRO1066" RELATED Gene-based [] synonym: "motilin-related peptide" EXACT [] synonym: "growth hormone secretagogue" EXACT [] synonym: "growth hormone-releasing peptide" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q9UBU3 name: appetite-regulating hormone (human) def: "An appetite-regulating hormone that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UBU3] comment: Category=organism-gene. synonym: "GHRL" RELATED Gene-based [UniProtKB:Q9UBU3] synonym: "MTLRP" RELATED Gene-based [UniProtKB:Q9UBU3] synonym: "hGHRL" EXACT PRO-short-label [PRO:DNx] synonym: "UNQ524/PRO1066" RELATED Gene-based [UniProtKB:Q9UBU3] synonym: "protein M46 (human)" EXACT [UniProtKB:Q9UBU3] synonym: "motilin-related peptide (human)" EXACT [UniProtKB:Q9UBU3] synonym: "growth hormone secretagogue (human)" EXACT [UniProtKB:Q9UBU3] synonym: "growth hormone-releasing peptide (human)" EXACT [UniProtKB:Q9UBU3] xref: UniProtKB:Q9UBU3 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000007973 ! appetite-regulating hormone relationship: has_gene_template HGNC:18129 ! GHRL (human)