[Term]
id: PR:000007885
name: 2-amino-3-ketobutyrate coenzyme A ligase
def: "A PLP-dependent alpha-oxoamine synthase that is a translation product of the human GCAT gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "KBL" RELATED Gene-based []
synonym: "GCAT" EXACT PRO-short-label [PRO:DNx]
synonym: "AKB ligase" BROAD [PRO:DNx]
synonym: "aminoacetone synthase" EXACT []
synonym: "glycine acetyltransferase" BROAD [PRO:DNx]
synonym: "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial" NARROW [PRO:DAN]
is_a: PR:000026124 ! PLP-dependent alpha-oxoamine synthase

[Term]
id: PR:000047515
name: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial, transit peptide removed form (human)
def: "A 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (human) that has had the transit peptide removed. UniProtKB:O75600, 22-419." [PRO:DNx, UniProtKB:O75600]
comment: Category=organism-modification.
synonym: "PRO_0000001246" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hGCAT/TransPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O75600, 22-419" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: PR:O75600 ! 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (human)
intersection_of: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O75600
name: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (human)
def: "A 2-amino-3-ketobutyrate coenzyme A ligase that is encoded in the genome of human." [PRO:CNA, UniProtKB:O75600]
comment: Category=organism-gene.
synonym: "KBL" RELATED Gene-based [UniProtKB:O75600]
synonym: "GCAT" RELATED Gene-based [UniProtKB:O75600]
synonym: "hGCAT" EXACT PRO-short-label [PRO:DNx]
synonym: "AKB ligase (human)" EXACT [UniProtKB:O75600]
synonym: "aminoacetone synthase (human)" EXACT [UniProtKB:O75600]
synonym: "glycine acetyltransferase (human)" EXACT [UniProtKB:O75600]
xref: UniProtKB:O75600
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007885 ! 2-amino-3-ketobutyrate coenzyme A ligase
relationship: has_gene_template HGNC:4188 ! GCAT (human)

[Term]
id: PR:O75600-1
name: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial isoform h1 (human)
def: "A 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75600-1." [PRO:DNx, UniProtKB:O75600]
comment: Category=organism-sequence.
synonym: "hGCAT/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O75600-1
is_a: PR:O75600 ! 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O75600-2
name: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial isoform h2 (human)
def: "A 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75600-2." [PRO:DNx, UniProtKB:O75600]
comment: Category=organism-sequence.
synonym: "hGCAT/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O75600-2
is_a: PR:O75600 ! 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens