[Term] id: PR:P39748-2 name: flap endonuclease 1 isoform FENMIT (human) def: "A flap endonuclease 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P39748-2." [PRO:DNx, UniProtKB:P39748] comment: Category=organism-sequence. synonym: "hFEN1/iso:FENMIT" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P39748-2 is_a: PR:P39748 ! flap endonuclease 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P39748-1 name: flap endonuclease 1 isoform 1 (human) def: "A flap endonuclease 1 isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. Requested by=PubChem. synonym: "hFEN1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P39748-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000039392 ! flap endonuclease 1 isoform 1 [Term] id: PR:Q54NU0 name: flap endonuclease 1 (Dictyostelium discoideum) def: "A flap endonuclease 1 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54NU0, PANTHER:PTHR11081:SF9, PRO:DNx] comment: Category=organism-gene. synonym: "repG" RELATED Gene-based [UniProtKB:Q54NU0] synonym: "Dicty-FEN1" EXACT PRO-short-label [PRO:DNx] synonym: "DDB_G0284987" RELATED Gene-based [UniProtKB:Q54NU0] synonym: "FEN-1 (Dictyostelium discoideum)" EXACT [UniProtKB:Q54NU0] synonym: "flap structure-specific endonuclease 1 (Dictyostelium discoideum)" EXACT [UniProtKB:Q54NU0] xref: UniProtKB:Q54NU0 intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum intersection_of: PR:000007457 ! flap endonuclease 1 relationship: has_gene_template dictyBase:DDB_G0284987 ! repG (Dictyostelium discoideum) [Term] id: PR:Q5ZLN4 name: flap endonuclease 1 (chicken) def: "A flap endonuclease 1 that is encoded in the genome of chicken." [OMA:Q5ZLN4, PANTHER:PTHR11081:SF9, PRO:DNx] comment: Category=organism-gene. synonym: "FEN1" RELATED Gene-based [UniProtKB:Q5ZLN4] synonym: "chick-FEN1" EXACT PRO-short-label [PRO:DNx] synonym: "RCJMB04_5g12" RELATED Gene-based [UniProtKB:Q5ZLN4] synonym: "FEN-1 (chicken)" EXACT [UniProtKB:Q5ZLN4] synonym: "flap structure-specific endonuclease 1 (chicken)" EXACT [UniProtKB:Q5ZLN4] xref: UniProtKB:Q5ZLN4 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000007457 ! flap endonuclease 1 relationship: has_gene_template NCBIGene:769677 ! FEN1 (chicken) [Term] id: PR:Q5A6K8 name: flap endonuclease 1 (Candida albicans SC5314) def: "A flap endonuclease 1 that is encoded in the genome of Candida albicans SC5314." [OMA:Q5A6K8, PRO:DNx] comment: Category=organism-gene. Note: Additional NCBIGenes (GeneIDs) listed in the UniProtKB entry have been reviewed and removed by PRO:DNx. synonym: "FEN1" RELATED Gene-based [UniProtKB:Q5A6K8] synonym: "RAD27" RELATED Gene-based [UniProtKB:Q5A6K8] synonym: "CaO19.547" RELATED Gene-based [UniProtKB:Q5A6K8] synonym: "Calb-FEN1" EXACT PRO-short-label [PRO:DNx] synonym: "CaO19.8182" RELATED Gene-based [UniProtKB:Q5A6K8] synonym: "CAALFM_CR04560CA" RELATED Gene-based [UniProtKB:Q5A6K8] synonym: "FEN-1 (Candida albicans SC5314)" EXACT [UniProtKB:Q5A6K8] synonym: "flap structure-specific endonuclease 1 (Candida albicans SC5314)" EXACT [UniProtKB:Q5A6K8] xref: UniProtKB:Q5A6K8 intersection_of: only_in_taxon NCBITaxon:237561 ! Candida albicans SC5314 intersection_of: PR:000007457 ! flap endonuclease 1 relationship: has_gene_template NCBIGene:3640946 ! RAD27 (Candida albicans SC5314) [Term] id: PR:000039392 name: flap endonuclease 1 isoform 1 def: "A flap endonuclease 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P39748-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "FEN1/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000007457 ! flap endonuclease 1 [Term] id: PR:Q9N3T2 name: flap endonuclease 1 (worm) def: "A flap endonuclease 1 that is encoded in the genome of worm." [OMA:Q9N3T2, PANTHER:PTHR11081:SF9, PRO:DNx] comment: Category=organism-gene. synonym: "crn-1" RELATED Gene-based [UniProtKB:Q9N3T2] synonym: "Y47G6A.8" RELATED Gene-based [UniProtKB:Q9N3T2] synonym: "FEN1 (worm)" EXACT PRO-short-label [PRO:DNx] synonym: "FEN-1 (worm)" EXACT [UniProtKB:Q9N3T2] synonym: "cell death-related nuclease 1 (worm)" EXACT [UniProtKB:Q9N3T2] synonym: "flap structure-specific endonuclease 1 (worm)" EXACT [UniProtKB:Q9N3T2] xref: UniProtKB:Q9N3T2 intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans intersection_of: PR:000007457 ! flap endonuclease 1 relationship: has_gene_template WormBase:WBGene00000794 ! crn-1 (worm) [Term] id: PR:Q5XIP6 name: flap endonuclease 1 (rat) def: "A flap endonuclease 1 that is encoded in the genome of rat." [OMA:Q5XIP6, PANTHER:PTHR11081:SF9, PRO:DNx] comment: Category=organism-gene. synonym: "Fen1" RELATED Gene-based [UniProtKB:Q5XIP6] synonym: "rFEN1" EXACT PRO-short-label [PRO:DNx] synonym: "FEN-1 (rat)" EXACT [UniProtKB:Q5XIP6] synonym: "flap structure-specific endonuclease 1 (rat)" EXACT [UniProtKB:Q5XIP6] xref: UniProtKB:Q5XIP6 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000007457 ! flap endonuclease 1 relationship: has_gene_template RGD:621821 ! Fen1 (rat) [Term] id: PR:Q6TNU4-1 name: flap endonuclease 1 isoform 1 (zebrafish) def: "A flap endonuclease 1 (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6TNU4-1." [PRO:DNx, UniProtKB:Q6TNU4] comment: Category=organism-sequence. synonym: "z-FEN1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q6TNU4-1 is_a: PR:Q6TNU4 ! flap endonuclease 1 (zebrafish) relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio [Term] id: PR:Q6TNU4-2 name: flap endonuclease 1 isoform 2 (zebrafish) def: "A flap endonuclease 1 (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6TNU4-2." [PRO:DNx, UniProtKB:Q6TNU4] comment: Category=organism-sequence. synonym: "z-FEN1/iso:2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q6TNU4-2 is_a: PR:Q6TNU4 ! flap endonuclease 1 (zebrafish) relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio [Term] id: PR:P39750 name: flap endonuclease 1 (Schizosaccharomyces pombe 972h-) def: "A flap endonuclease 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:P39750, PANTHER:PTHR11081:SF9, PRO:DNx] comment: Category=organism-gene. synonym: "fen1" RELATED Gene-based [UniProtKB:P39750] synonym: "rad2" RELATED Gene-based [UniProtKB:P39750] synonym: "SPAC3G6.06c" RELATED Gene-based [UniProtKB:P39750] synonym: "Spom972h-FEN1" EXACT PRO-short-label [PRO:DNx] synonym: "FEN-1 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P39750] synonym: "DNA repair protein rad2 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P39750] synonym: "flap structure-specific endonuclease 1 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P39750] xref: UniProtKB:P39750 intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h- intersection_of: PR:000007457 ! flap endonuclease 1 relationship: has_gene_template PomBase:SPAC3G6.06c ! rad2 (Schizosaccharomyces pombe) [Term] id: PR:O65251 name: flap endonuclease 1 (Arabidopsis thaliana) def: "A flap endonuclease 1 that is encoded in the genome of Arabidopsis thaliana." [OMA:O65251, PANTHER:PTHR11081:SF9, PRO:DNx] comment: Category=organism-gene. synonym: "FEN1" RELATED Gene-based [UniProtKB:O65251] synonym: "At-FEN1" EXACT PRO-short-label [PRO:DNx] synonym: "F21E10.3" RELATED Gene-based [UniProtKB:O65251] synonym: "At5g26680" RELATED Gene-based [UniProtKB:O65251] synonym: "FEN-1 (Arabidopsis thaliana)" EXACT [UniProtKB:O65251] synonym: "flap structure-specific endonuclease 1 (Arabidopsis thaliana)" EXACT [UniProtKB:O65251] xref: UniProtKB:O65251 intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana intersection_of: PR:000007457 ! flap endonuclease 1 relationship: has_gene_template Araport:AT5G26680 ! FEN1 (Arabidopsis thaliana) [Term] id: PR:Q7K7A9 name: flap endonuclease 1 (fruit fly) def: "A flap endonuclease 1 that is encoded in the genome of fruit fly." [OMA:Q7K7A9, PANTHER:PTHR11081:SF9, PRO:DNx] comment: Category=organism-gene. synonym: "Fen1" RELATED Gene-based [UniProtKB:Q7K7A9] synonym: "CG8648" RELATED Gene-based [UniProtKB:Q7K7A9] synonym: "fly-FEN1" EXACT PRO-short-label [PRO:DNx] synonym: "FEN-1 (fruit fly)" EXACT [UniProtKB:Q7K7A9] synonym: "flap structure-specific endonuclease 1 (fruit fly)" EXACT [UniProtKB:Q7K7A9] xref: UniProtKB:Q7K7A9 intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster intersection_of: PR:000007457 ! flap endonuclease 1 relationship: has_gene_template FlyBase:FBgn0025832 ! Fen1 (fruit fly) [Term] id: PR:000007457 name: flap endonuclease 1 def: "A protein that is a translation product of the human FEN1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "MF1" EXACT [] synonym: "FEN1" EXACT PRO-short-label [PRO:DNx] synonym: "RAD2" RELATED Gene-based [] synonym: "FEN-1" EXACT [] synonym: "DNase IV" EXACT [] synonym: "maturation factor 1" EXACT [] synonym: "flap structure-specific endonuclease 1" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q6TNU4 name: flap endonuclease 1 (zebrafish) def: "A flap endonuclease 1 that is encoded in the genome of zebrafish." [OMA:Q6TNU4, PANTHER:PTHR11081:SF9, PRO:DNx] comment: Category=organism-gene. synonym: "fen1" RELATED Gene-based [UniProtKB:Q6TNU4] synonym: "z-FEN1" EXACT PRO-short-label [PRO:DNx] synonym: "FEN-1 (zebrafish)" EXACT [UniProtKB:Q6TNU4] synonym: "flap structure-specific endonuclease 1 (zebrafish)" EXACT [UniProtKB:Q6TNU4] xref: UniProtKB:Q6TNU4 intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio intersection_of: PR:000007457 ! flap endonuclease 1 relationship: has_gene_template ZFIN:ZDB-GENE-031112-11 ! fen1 (zebrafish) [Term] id: PR:P26793 name: flap endonuclease 1 (yeast) def: "A flap endonuclease 1 that is encoded in the genome of yeast." [OMA:P26793, PANTHER:PTHR11081:SF9, PRO:DNx] comment: Category=organism-gene. synonym: "FEN1" RELATED Gene-based [UniProtKB:P26793] synonym: "RTH1" RELATED Gene-based [UniProtKB:P26793] synonym: "RAD27" RELATED Gene-based [UniProtKB:P26793] synonym: "yFEN1" EXACT PRO-short-label [PRO:DNx] synonym: "YKL510" RELATED Gene-based [UniProtKB:P26793] synonym: "YKL113C" RELATED Gene-based [UniProtKB:P26793] synonym: "FEN-1 (yeast)" EXACT [UniProtKB:P26793] synonym: "RTH1 nuclease (yeast)" EXACT [UniProtKB:P26793] synonym: "RAD2 homolog nuclease 1 (yeast)" EXACT [UniProtKB:P26793] synonym: "structure-specific endonuclease RAD27 (yeast)" EXACT [UniProtKB:P26793] synonym: "flap structure-specific endonuclease 1 (yeast)" EXACT [UniProtKB:P26793] xref: UniProtKB:P26793 intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C intersection_of: PR:000007457 ! flap endonuclease 1 relationship: has_gene_template SGD:S000001596 ! RAD27 (yeast) [Term] id: PR:P39749 name: flap endonuclease 1 (mouse) def: "A flap endonuclease 1 that is encoded in the genome of mouse." [OMA:P39749, PRO:DNx] comment: Category=organism-gene. synonym: "Fen1" RELATED Gene-based [UniProtKB:P39749] synonym: "Fen-1" RELATED Gene-based [UniProtKB:P39749] synonym: "mFEN1" EXACT PRO-short-label [PRO:DNx] synonym: "FEN-1 (mouse)" EXACT [UniProtKB:P39749] synonym: "flap structure-specific endonuclease 1 (mouse)" EXACT [UniProtKB:P39749] xref: UniProtKB:P39749 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000007457 ! flap endonuclease 1 relationship: has_gene_template MGI:102779 ! Fen1 (mouse) [Term] id: PR:Q5XIP6-1 name: flap endonuclease 1 isoform 1 (rat) def: "A flap endonuclease 1 isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rFEN1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q5XIP6-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000039392 ! flap endonuclease 1 isoform 1 [Term] id: PR:P39748 name: flap endonuclease 1 (human) def: "A flap endonuclease 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-gene. synonym: "FEN1" RELATED Gene-based [UniProtKB:P39748] synonym: "RAD2" RELATED Gene-based [UniProtKB:P39748] synonym: "hFEN1" EXACT PRO-short-label [PRO:DNx] synonym: "hFEN-1" EXACT [UniProtKB:P39748] synonym: "MF1 (human)" EXACT [UniProtKB:P39748] synonym: "FEN-1 (human)" EXACT [UniProtKB:P39748] synonym: "DNase IV (human)" EXACT [UniProtKB:P39748] synonym: "maturation factor 1 (human)" EXACT [UniProtKB:P39748] synonym: "flap structure-specific endonuclease 1 (human)" EXACT [UniProtKB:P39748] xref: Reactome:R-HSA-54745 "PR:P39748 located_in GO:0005654" xref: UniProtKB:P39748 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000007457 ! flap endonuclease 1 relationship: has_gene_template HGNC:3650 ! FEN1 (human) [Term] id: PR:O65251-1 name: flap endonuclease 1 isoform 1 (Arabidopsis thaliana) def: "A flap endonuclease 1 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O65251-1." [PRO:DNx, UniProtKB:O65251] comment: Category=organism-sequence. synonym: "At-FEN1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O65251-1 is_a: PR:O65251 ! flap endonuclease 1 (Arabidopsis thaliana) relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana