[Term]
id: PR:000007323
name: fumarylacetoacetase
def: "A protein that is a translation product of the human FAH gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "FAA" EXACT []
synonym: "FAH" EXACT PRO-short-label [PRO:DNx]
synonym: "beta-diketonase" EXACT []
synonym: "fumarylacetoacetate hydrolase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q1ZXQ1
name: fumarylacetoacetase (Dictyostelium discoideum)
def: "A fumarylacetoacetase that is encoded in the genome of Dictyostelium discoideum." [OMA:Q1ZXQ1, PRO:DNx]
comment: Category=organism-gene.
synonym: "fah" RELATED Gene-based [UniProtKB:Q1ZXQ1]
synonym: "Dicty-FAH" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0271094" RELATED Gene-based [UniProtKB:Q1ZXQ1]
synonym: "FAA (Dictyostelium discoideum)" EXACT [UniProtKB:Q1ZXQ1]
synonym: "beta-diketonase (Dictyostelium discoideum)" EXACT [UniProtKB:Q1ZXQ1]
synonym: "fumarylacetoacetate hydrolase (Dictyostelium discoideum)" EXACT [UniProtKB:Q1ZXQ1]
xref: UniProtKB:Q1ZXQ1
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000007323 ! fumarylacetoacetase
relationship: has_gene_template dictyBase:DDB_G0271094 ! fah (Dictyostelium discoideum)

[Term]
id: PR:P25093-1
name: fumarylacetoacetase isoform 1 (rat)
def: "A fumarylacetoacetase isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rFAH/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P25093-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000038965 ! fumarylacetoacetase isoform 1

[Term]
id: PR:000026566
name: fumarylacetoacetase, initiator methionine removed form
def: "A fumarylacetoacetase that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "FAH/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000007323 ! fumarylacetoacetase
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:P16930
name: fumarylacetoacetase (human)
def: "A fumarylacetoacetase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P16930]
comment: Category=organism-gene.
synonym: "FAH" RELATED Gene-based [UniProtKB:P16930]
synonym: "hFAH" EXACT PRO-short-label [PRO:DNx]
synonym: "FAA (human)" EXACT [UniProtKB:P16930]
synonym: "beta-diketonase (human)" EXACT [UniProtKB:P16930]
synonym: "fumarylacetoacetate hydrolase (human)" EXACT [UniProtKB:P16930]
xref: UniProtKB:P16930
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007323 ! fumarylacetoacetase
relationship: has_gene_template HGNC:3579 ! FAH (human)

[Term]
id: PR:P35505-1
name: fumarylacetoacetase isoform 1 (mouse)
def: "A fumarylacetoacetase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mFAH/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35505-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038965 ! fumarylacetoacetase isoform 1

[Term]
id: PR:P25093
name: fumarylacetoacetase (rat)
def: "A fumarylacetoacetase that is encoded in the genome of rat." [OMA:P25093, PANTHER:PTHR11820:SF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "Fah" RELATED Gene-based [UniProtKB:P25093]
synonym: "rFAH" EXACT PRO-short-label [PRO:DNx]
synonym: "FAA (rat)" EXACT [UniProtKB:P25093]
synonym: "beta-diketonase (rat)" EXACT [UniProtKB:P25093]
synonym: "fumarylacetoacetate hydrolase (rat)" EXACT [UniProtKB:P25093]
xref: UniProtKB:P25093
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000007323 ! fumarylacetoacetase
relationship: has_gene_template RGD:61932 ! Fah (rat)

[Term]
id: PR:P16930-2
name: fumarylacetoacetase isoform h2 (human)
def: "A fumarylacetoacetase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16930-2." [PRO:DNx, UniProtKB:P16930]
comment: Category=organism-sequence.
synonym: "hFAH/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P16930-2
is_a: PR:P16930 ! fumarylacetoacetase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P16930-1
name: fumarylacetoacetase isoform 1 (human)
def: "A fumarylacetoacetase isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hFAH/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P16930-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038965 ! fumarylacetoacetase isoform 1

[Term]
id: PR:000047363
name: fumarylacetoacetase, initiator methionine removed form (human)
def: "A fumarylacetoacetase (human) that has had the initiator methionine removed. UniProtKB:P16930, 2-419." [PRO:DNx, Reactome:R-HSA-71174]
comment: Category=organism-modification.
synonym: "hFAH/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000156825" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P16930, 2-419" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-71174 "PR:000047363 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P16930 ! fumarylacetoacetase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8RW90
name: fumarylacetoacetase (Arabidopsis thaliana)
def: "A fumarylacetoacetase that is encoded in the genome of Arabidopsis thaliana." [OMA:Q8RW90, PRO:DNx]
comment: Category=organism-gene.
synonym: "FAH" RELATED Gene-based [UniProtKB:Q8RW90]
synonym: "AtFAH" EXACT [UniProtKB:Q8RW90]
synonym: "SSCD1" RELATED Gene-based [UniProtKB:Q8RW90]
synonym: "At-FAH" EXACT PRO-short-label [PRO:DNx]
synonym: "F12F1.8" RELATED Gene-based [UniProtKB:Q8RW90]
synonym: "At1g12050" RELATED Gene-based [UniProtKB:Q8RW90]
synonym: "fumarylacetoacetate hydrolase (Arabidopsis thaliana)" EXACT [UniProtKB:Q8RW90]
synonym: "protein SHORT-DAY SENSITIVE CELL DEATH 1 (Arabidopsis thaliana)" EXACT [UniProtKB:Q8RW90]
xref: UniProtKB:Q8RW90
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000007323 ! fumarylacetoacetase
relationship: has_gene_template Araport:AT1G12050 ! FAH (Arabidopsis thaliana)

[Term]
id: PR:Q94272
name: fumarylacetoacetase (worm)
def: "A fumarylacetoacetase that is encoded in the genome of worm." [OMA:Q94272, PRO:DNx]
comment: Category=organism-gene.
synonym: "fah-1" RELATED Gene-based [UniProtKB:Q94272]
synonym: "phi-43" RELATED Gene-based [UniProtKB:Q94272]
synonym: "K10C2.4" RELATED Gene-based [UniProtKB:Q94272]
synonym: "FAA (worm)" EXACT [UniProtKB:Q94272]
synonym: "FAH (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "beta-diketonase (worm)" EXACT [UniProtKB:Q94272]
synonym: "fumarylacetoacetate hydrolase (worm)" EXACT [UniProtKB:Q94272]
xref: UniProtKB:Q94272
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000007323 ! fumarylacetoacetase
relationship: has_gene_template WormBase:WBGene00019620 ! fah-1 (worm)

[Term]
id: PR:P35505
name: fumarylacetoacetase (mouse)
def: "A fumarylacetoacetase that is encoded in the genome of mouse." [OMA:P35505, PRO:DNx]
comment: Category=organism-gene.
synonym: "Fah" RELATED Gene-based [UniProtKB:P35505]
synonym: "mFAH" EXACT PRO-short-label [PRO:DNx]
synonym: "FAA (mouse)" EXACT [UniProtKB:P35505]
synonym: "beta-diketonase (mouse)" EXACT [UniProtKB:P35505]
synonym: "fumarylacetoacetate hydrolase (mouse)" EXACT [UniProtKB:P35505]
xref: UniProtKB:P35505
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000007323 ! fumarylacetoacetase
relationship: has_gene_template MGI:95482 ! Fah (mouse)

[Term]
id: PR:000038965
name: fumarylacetoacetase isoform 1
def: "A fumarylacetoacetase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16930-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "FAH/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000007323 ! fumarylacetoacetase