[Term]
id: PR:P60330
name: separin (mouse)
def: "A separin that is encoded in the genome of mouse." [OMA:P60330, PRO:DNx]
comment: Category=organism-gene.
synonym: "Esp1" RELATED Gene-based [UniProtKB:P60330]
synonym: "Espl1" RELATED Gene-based [UniProtKB:P60330]
synonym: "mESPL1" EXACT PRO-short-label [PRO:DNx]
synonym: "Kiaa0165" RELATED Gene-based [UniProtKB:P60330]
synonym: "separase (mouse)" EXACT [UniProtKB:P60330]
synonym: "caspase-like protein ESPL1 (mouse)" EXACT [UniProtKB:P60330]
synonym: "extra spindle poles-like 1 protein (mouse)" EXACT [UniProtKB:P60330]
xref: UniProtKB:P60330
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000007201 ! separin
relationship: has_gene_template MGI:2146156 ! Espl1 (mouse)

[Term]
id: PR:Q5IBC5-2
name: separase isoform 2 (Arabidopsis thaliana)
def: "A separase (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5IBC5-2." [PRO:DNx, UniProtKB:Q5IBC5]
comment: Category=organism-sequence.
synonym: "At-ESPL1/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q5IBC5-2
is_a: PR:Q5IBC5 ! separase (Arabidopsis thaliana)
relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana

[Term]
id: PR:Q5IBC5
name: separase (Arabidopsis thaliana)
def: "A separin that is encoded in the genome of Arabidopsis thaliana." [PANTHER:PTHR12792:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "ESP" RELATED Gene-based [UniProtKB:Q5IBC5]
synonym: "AESP" RELATED Gene-based [UniProtKB:Q5IBC5]
synonym: "ESP1" RELATED Gene-based [UniProtKB:Q5IBC5]
synonym: "RSW4" RELATED Gene-based [UniProtKB:Q5IBC5]
synonym: "AtESP" RELATED Gene-based [UniProtKB:Q5IBC5]
synonym: "At-ESPL1" EXACT PRO-short-label [PRO:DNx]
synonym: "At4g22970" RELATED Gene-based [UniProtKB:Q5IBC5]
synonym: "F7H19.150" RELATED Gene-based [UniProtKB:Q5IBC5]
synonym: "protein RADIALLY SWOLLEN 4 (Arabidopsis thaliana)" EXACT [UniProtKB:Q5IBC5]
synonym: "protein EXTRA SPINDLE POLES (Arabidopsis thaliana)" EXACT [UniProtKB:Q5IBC5]
xref: UniProtKB:Q5IBC5
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000007201 ! separin
relationship: has_gene_template Araport:AT4G22970 ! ESP1 (Arabidopsis thaliana)

[Term]
id: PR:Q54G81
name: uncharacterized protein, espl1 translation product (Dictyostelium discoideum)
def: "A separin that is encoded in the genome of Dictyostelium discoideum." [PANTHER:PTHR12792:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dicty-ESPL1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q54G81
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000007201 ! separin
relationship: has_gene_template dictyBase:DDB_G0290325 ! espl1 (Dictyostelium discoideum)

[Term]
id: PR:Q5IBC5-1
name: separase isoform 1 (Arabidopsis thaliana)
def: "A separase (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5IBC5-1." [PRO:DNx, UniProtKB:Q5IBC5]
comment: Category=organism-sequence.
synonym: "At-ESPL1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q5IBC5-1
is_a: PR:Q5IBC5 ! separase (Arabidopsis thaliana)
relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana

[Term]
id: PR:P18296
name: separin (Schizosaccharomyces pombe 972h-)
def: "A separin that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PANTHER:PTHR12792:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "cut1" RELATED Gene-based [UniProtKB:P18296]
synonym: "SPCC5E4.04" RELATED Gene-based [UniProtKB:P18296]
synonym: "Spom972h-ESPL1" EXACT PRO-short-label [PRO:DNx]
synonym: "separase (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P18296]
synonym: "cell untimely torn protein 1 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P18296]
xref: UniProtKB:P18296
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000007201 ! separin
relationship: has_gene_template PomBase:SPCC5E4.04 ! cut1 (Schizosaccharomyces pombe)

[Term]
id: PR:Q14674
name: separin (human)
def: "A separin that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14674]
comment: Category=organism-gene.
synonym: "ESP1" RELATED Gene-based [UniProtKB:Q14674]
synonym: "ESPL1" RELATED Gene-based [UniProtKB:Q14674]
synonym: "hESPL1" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0165" RELATED Gene-based [UniProtKB:Q14674]
synonym: "separase (human)" EXACT [UniProtKB:Q14674]
synonym: "caspase-like protein ESPL1 (human)" EXACT [UniProtKB:Q14674]
synonym: "extra spindle poles-like 1 protein (human)" EXACT [UniProtKB:Q14674]
xref: Reactome:R-HSA-1638167 "PR:Q14674 located_in GO:0005829"
xref: UniProtKB:Q14674
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007201 ! separin
relationship: has_gene_template HGNC:16856 ! ESPL1 (human)

[Term]
id: PR:000007201
name: separin
def: "A protein that is a translation product of the human ESPL1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ESP1" RELATED Gene-based []
synonym: "ESPL1" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0165" RELATED Gene-based []
synonym: "separase" EXACT []
synonym: "caspase-like protein ESPL1" EXACT []
synonym: "extra spindle poles-like 1 protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q14674-2
name: separin isoform h2 (human)
def: "A separin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14674-2." [PRO:DNx, UniProtKB:Q14674]
comment: Category=organism-sequence.
synonym: "hESPL1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q14674-2
is_a: PR:Q14674 ! separin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q14674-1
name: separin isoform h1 (human)
def: "A separin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14674-1." [PRO:DNx, UniProtKB:Q14674]
comment: Category=organism-sequence.
synonym: "hESPL1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q14674-1
is_a: PR:Q14674 ! separin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9VRN6
name: LD08709p (fruit fly)
def: "A separin that is encoded in the genome of fruit fly." [PANTHER:PTHR12792:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "CG10583" RELATED Gene-based [UniProtKB:Q9VRN6]
synonym: "fly-ESPL1" EXACT PRO-short-label [PRO:DNx]
synonym: "separase (fruit fly)" EXACT [UniProtKB:Q9VRN6]
xref: UniProtKB:Q9VRN6
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000007201 ! separin
relationship: has_gene_template FlyBase:FBgn0035627 ! Sse (fruit fly)