[Term]
id: PR:000049815
name: epidermal growth factor receptor, signal peptide removed form (mouse)
def: "An epidermal growth factor receptor, signal peptide removed form in mouse. UniProtKB:Q01279, 25-1210." [PRO:CNA]
comment: Category=organism-modification. Evidence=(ECO:0000305).
synonym: "mEGFR/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q01279, 25-1210" EXACT PRO-proteoform-std [PRO:DAN]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000019753 ! epidermal growth factor receptor, signal peptide removed form

[Term]
id: PR:000051035
name: epidermal growth factor receptor N-glycosylated 9 (human)
def: "An epidermal growth factor receptor (human) that has been N-glycosylated at the residue equivalent to Asn-56 of the amino acid sequence represented by UniProtKB:P00533-1, in which the glycan structure is represented by GlyTouCan:G83461WR. Example: UniProtKB:P00533-1, Asn-56, MOD:00160~GNO:G83461WR." [GlyGen:P00533-1, PMID:10731668, PMID:10988252, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hEGFR/NGlyco:9" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-56, MOD:00160~GNO:G83461WR" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-56, MOD:00160~UniCarbKB:2921" NARROW [PRO:DNx]
is_a: PR:P00533 ! epidermal growth factor receptor (human)
relationship: has_part GNO:G83461WR ! G83461WR
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051037
name: epidermal growth factor receptor N-glycosylated 11 (human)
def: "An epidermal growth factor receptor (human) that has been N-glycosylated at the residue equivalent to Asn-603 of the amino acid sequence represented by UniProtKB:P00533-1, in which the glycan structure is represented by GlyTouCan:G83461WR. Example: UniProtKB:P00533-1, Asn-603, MOD:00160~GNO:G83461WR." [GlyGen:P00533-1, PMID:10731668, PMID:10988252, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hEGFR/NGlyco:11" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-603, MOD:00160~GNO:G83461WR" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-603, MOD:00160~UniCarbKB:2921" NARROW [PRO:DNx]
is_a: PR:P00533 ! epidermal growth factor receptor (human)
relationship: has_part GNO:G83461WR ! G83461WR
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051036
name: epidermal growth factor receptor N-glycosylated 10 (human)
def: "An epidermal growth factor receptor (human) that has been N-glycosylated at the residue equivalent to Asn-568 of the amino acid sequence represented by UniProtKB:P00533-1, in which the glycan structure is represented by GlyTouCan:G83461WR. Example: UniProtKB:P00533-1, Asn-568, MOD:00160~GNO:G83461WR." [GlyGen:P00533-1, PMID:10731668, PMID:10988252, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hEGFR/NGlyco:10" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-568, MOD:00160~GNO:G83461WR" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-568, MOD:00160~UniCarbKB:2921" NARROW [PRO:DNx]
is_a: PR:P00533 ! epidermal growth factor receptor (human)
relationship: has_part GNO:G83461WR ! G83461WR
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000028422
name: epidermal growth factor receptor, signal peptide removed form (human)
def: "An epidermal growth factor receptor, signal peptide removed form in human. Example: UniProtKB:P00533-1, 25-1210." [PRO:DNx]
comment: Category=organism-modification.
synonym: "hEGFR/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000016665" NARROW PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P00533-1, 25-1210" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-179837 "PR:000028422 located_in GO:0005886"
xref: Reactome:R-HSA-9611160 "PR:000028422 located_in GO:0010008"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000019753 ! epidermal growth factor receptor, signal peptide removed form

[Term]
id: PR:000051034
name: epidermal growth factor receptor N-glycosylated 8 (human)
def: "An epidermal growth factor receptor (human) that has been N-glycosylated at the residue equivalent to Asn-56 of the amino acid sequence represented by UniProtKB:P00533-1, in which the glycan structure is represented by GlyTouCan:G78059CC. Example: UniProtKB:P00533-1, Asn-56, MOD:00160~GNO:G78059CC." [GlyGen:P00533-1, PMID:10731668, PMID:10988252, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hEGFR/NGlyco:8" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-56, MOD:00160~GNO:G78059CC" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-56, MOD:00160~UniCarbKB:1603" NARROW [PRO:DNx]
is_a: PR:P00533 ! epidermal growth factor receptor (human)
relationship: has_part GNO:G78059CC ! G78059CC
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051033
name: epidermal growth factor receptor N-glycosylated 7 (human)
def: "An epidermal growth factor receptor (human) that has been N-glycosylated at the residue equivalent to Asn-528 of the amino acid sequence represented by UniProtKB:P00533-1, in which the glycan structure is represented by GlyTouCan:G83461WR. Example: UniProtKB:P00533-1, Asn-528, MOD:00160~GNO:G83461WR." [GlyGen:P00533-1, PMID:10731668, PMID:10988252, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hEGFR/NGlyco:7" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-528, MOD:00160~GNO:G83461WR" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-528, MOD:00160~UniCarbKB:2921" NARROW [PRO:DNx]
is_a: PR:P00533 ! epidermal growth factor receptor (human)
relationship: has_part GNO:G83461WR ! G83461WR
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051032
name: epidermal growth factor receptor N-glycosylated 6 (human)
def: "An epidermal growth factor receptor (human) that has been N-glycosylated at the residue equivalent to Asn-444 of the amino acid sequence represented by UniProtKB:P00533-1, in which the glycan structure is represented by GlyTouCan:G83461WR. Example: UniProtKB:P00533-1, Asn-444, MOD:00160~GNO:G83461WR." [GlyGen:P00533-1, PMID:10731668, PMID:10988252, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hEGFR/NGlyco:6" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-444, MOD:00160~GNO:G83461WR" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-444, MOD:00160~UniCarbKB:2921" NARROW [PRO:DNx]
is_a: PR:P00533 ! epidermal growth factor receptor (human)
relationship: has_part GNO:G83461WR ! G83461WR
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051031
name: epidermal growth factor receptor N-glycosylated 5 (human)
def: "An epidermal growth factor receptor (human) that has been N-glycosylated at the residue equivalent to Asn-413 of the amino acid sequence represented by UniProtKB:P00533-1, in which the glycan structure is represented by GlyTouCan:G83461WR. Example: UniProtKB:P00533-1, Asn-413, MOD:00160~GNO:G83461WR." [GlyGen:P00533-1, PMID:10731668, PMID:10988252, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hEGFR/NGlyco:5" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-413, MOD:00160~GNO:G83461WR" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-413, MOD:00160~UniCarbKB:2921" NARROW [PRO:DNx]
is_a: PR:P00533 ! epidermal growth factor receptor (human)
relationship: has_part GNO:G83461WR ! G83461WR
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051030
name: epidermal growth factor receptor N-glycosylated 4 (human)
def: "An epidermal growth factor receptor (human) that has been N-glycosylated at the residue equivalent to Asn-361 of the amino acid sequence represented by UniProtKB:P00533-1, in which the glycan structure is represented by GlyTouCan:G83461WR. Example: UniProtKB:P00533-1, Asn-361, MOD:00160~GNO:G83461WR." [GlyGen:P00533-1, PMID:10731668, PMID:10988252, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hEGFR/NGlyco:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-361, MOD:00160~GNO:G83461WR" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-361, MOD:00160~UniCarbKB:2921" NARROW [PRO:DNx]
is_a: PR:P00533 ! epidermal growth factor receptor (human)
relationship: has_part GNO:G83461WR ! G83461WR
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q01279-1
name: epidermal growth factor receptor isoform 1 (mouse)
def: "An epidermal growth factor receptor isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mEGFR/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q01279-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027474 ! epidermal growth factor receptor isoform 1

[Term]
id: PR:P00533
name: epidermal growth factor receptor (human)
def: "An epidermal growth factor receptor that is encoded in the genome of human." [PRO:DNx, UniProtKB:P00533]
comment: Category=organism-gene.
synonym: "EGFR" RELATED Gene-based [UniProtKB:P00533]
synonym: "ERBB" RELATED Gene-based [UniProtKB:P00533]
synonym: "HER1" RELATED Gene-based [UniProtKB:P00533]
synonym: "ERBB1" RELATED Gene-based [UniProtKB:P00533]
synonym: "hEGFR" EXACT PRO-short-label [PRO:DNx]
synonym: "proto-oncogene c-ErbB-1 (human)" EXACT [UniProtKB:P00533]
synonym: "receptor tyrosine-protein kinase erbB-1 (human)" EXACT [UniProtKB:P00533]
xref: DTO:03100124
xref: UniProtKB:P00533
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006933 ! epidermal growth factor receptor
relationship: has_gene_template HGNC:3236 ! EGFR (human)

[Term]
id: PR:000049850
name: epidermal growth factor receptor, signal peptide removed unphosphorylated 3 (human)
def: "An epidermal growth factor receptor, signal peptide removed form (human) that lacks phosphoserines at the C-terminal tail, at positions 1070, 1071, 1081, and 1166 of the amino acid sequence represented by UniProtKB:P00533-1. Example: UniProtKB:P00533-1, 25-1210, Ser-1070/Ser-1071/Ser-1081/Ser-1166, PR:000026291." [PMID:10347170, PRO:KER]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:10347170).
synonym: "hEGFR/SigPep-/UnPhos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00533-1, 25-1210, Ser-1070/Ser-1071/Ser-1081/Ser-1166, PR:000026291" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:000028422 ! epidermal growth factor receptor, signal peptide removed form (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049851
name: epidermal growth factor receptor, signal peptide removed phosphorylated 4 (human)
def: "An epidermal growth factor receptor, signal peptide removed form (human) that has been post-translationally modified on an inhibitory site located in the kinase domain (sub-kinase domain III) corresponding to a phosphoserine at position 768 of the amino acid sequence represented by UniProtKB:P00533-1. Example: UniProtKB:P00533-1, 25-1210, Ser-768, MOD:00046." [PMID:10347170, PRO:KER]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:10347170). Kinase=("CAMKII"; PR:000003197; Ser-768).
synonym: "hEGFR/SigPep-/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00533-1, 25-1210, Ser-768, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:000028422 ! epidermal growth factor receptor, signal peptide removed form (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049852
name: epidermal growth factor receptor, signal peptide removed unphosphorylated 4 (human)
def: "An epidermal growth factor receptor, signal peptide removed form (human) that has not been phosphorylated at the position equivalent to Ser-768 of the amino acid sequence represented by UniProtKB:P00533-1. Example: UniProtKB:P00533-1, 25-1210, Ser-768, PR:000026291." [PMID:10347170, PRO:KER]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:10347170).
synonym: "hEGFR/SigPep-/UnPhos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00533-1, 25-1210, Ser-768, PR:000026291" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:000028422 ! epidermal growth factor receptor, signal peptide removed form (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000006933
name: epidermal growth factor receptor
def: "An EGF receptor type tyrosine-protein kinase that is a translation product of the human EGFR gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "EGFR" EXACT PRO-short-label [PRO:DNx]
synonym: "ERBB" RELATED Gene-based []
synonym: "HER1" RELATED Gene-based []
synonym: "ERBB1" RELATED Gene-based []
synonym: "proto-oncogene c-ErbB-1" EXACT []
synonym: "receptor tyrosine-protein kinase erbB-1" EXACT []
xref: IUPHARobj:1797
is_a: PR:000001812 ! EGF receptor type tyrosine-protein kinase

[Term]
id: PR:000019753
name: epidermal growth factor receptor, signal peptide removed form
def: "An epidermal growth factor receptor that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "EGFR/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000006933 ! epidermal growth factor receptor
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000049816
name: epidermal growth factor receptor, signal peptide removed phosphorylated 1 (mouse)
def: "An epidermal growth factor receptor, signal peptide removed form (mouse) that has been phosphorylated at the position equivalent to Ser-993 of the amino acid sequence represented by UniProtKB:Q01279. UniProtKB:Q01279, 25-1210, Ser-993, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000305, for signal peptide removal). Evidence=(ECO:0006055, based on PMID:21183079).
synonym: "mEGFR/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q01279, 25-1210, Ser-993, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:000049815 ! epidermal growth factor receptor, signal peptide removed form (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049817
name: epidermal growth factor receptor, signal peptide removed phosphorylated 2 (mouse)
def: "An epidermal growth factor receptor, signal peptide removed form (mouse) that has been phosphorylated at the position equivalent to Thr-995 of the amino acid sequence represented by UniProtKB:Q01279. UniProtKB:Q01279, 25-1210, Thr-995, MOD:00047." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000305, for signal peptide removal). Evidence=(ECO:0006055, based on PMID:21183079).
synonym: "mEGFR/SigPep-/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q01279, 25-1210, Thr-995, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:000049815 ! epidermal growth factor receptor, signal peptide removed form (mouse)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000047261
name: epidermal growth factor receptor, signal peptide removed phosphorylated 1 (human)
def: "An epidermal growth factor receptor, signal peptide removed form (human) that has been post-translationally modified by autocatalysis to include phosphotyrosine at positions 1092, 1110, 1172 and 1197 of the amino acid sequence represented by UniProtKB:P00533. UniProtKB:P00533, 25-1210, Tyr-1092/Tyr-1110/Tyr-1172/Tyr-1197, MOD:00048." [PRO:DAN, Reactome:R-HSA-180287]
comment: Category=organism-modification.
synonym: "hEGFR/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000016665, Tyr-1092/Tyr-1110/Tyr-1172/Tyr-1197, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P00533, 25-1210, Tyr-1092/Tyr-1110/Tyr-1172/Tyr-1197, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-180287 "PR:000047261 located_in GO:0005886"
is_a: PR:000028422 ! epidermal growth factor receptor, signal peptide removed form (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047262
name: epidermal growth factor receptor, signal peptide removed phosphorylated 2 (human)
def: "An epidermal growth factor receptor, signal peptide removed form (human) that has been post-translationally modified to include phosphotyrosine at positions 1016, 1069, 1092, 1110, 1172 and 1197 of the amino acid sequence represented by UniProtKB:P00533. UniProtKB:P00533, 25-1210, Tyr-1016/Tyr-1069/Tyr-1092/Tyr-1110/Tyr-1172/Tyr-1197, MOD:00048." [PRO:DNx, Reactome:R-HSA-179803, Reactome:R-HSA-8869138]
comment: Category=organism-modification.
synonym: "hEGFR/SigPep-/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000016665, Tyr-1016/Tyr-1069/Tyr-1092/Tyr-1110/Tyr-1172/Tyr-1197, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P00533, 25-1210, Tyr-1016/Tyr-1069/Tyr-1092/Tyr-1110/Tyr-1172/Tyr-1197, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-179803 "PR:000047262 located_in GO:0005886"
xref: Reactome:R-HSA-8869138 "PR:000047262 located_in GO:0030665"
is_a: PR:000028422 ! epidermal growth factor receptor, signal peptide removed form (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049818
name: epidermal growth factor receptor, signal peptide removed phosphorylated 3 (mouse)
def: "An epidermal growth factor receptor, signal peptide removed form (mouse) that has been phosphorylated at the position equivalent to Ser-997 of the amino acid sequence represented by UniProtKB:Q01279. UniProtKB:Q01279, 25-1210, Ser-997, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000305, for signal peptide removal). Evidence=(ECO:0006055, based on PMID:21183079).
synonym: "mEGFR/SigPep-/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q01279, 25-1210, Ser-997, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:000049815 ! epidermal growth factor receptor, signal peptide removed form (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049819
name: epidermal growth factor receptor, signal peptide removed phosphorylated 4 (mouse)
def: "An epidermal growth factor receptor, signal peptide removed form (mouse) that has been phosphorylated at the position equivalent to Ser-1162 of the amino acid sequence represented by UniProtKB:Q01279. UniProtKB:Q01279, 25-1210, Ser-1162, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000305, for signal peptide removal). Evidence=(ECO:0006055, based on PMID:21183079).
synonym: "mEGFR/SigPep-/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q01279, 25-1210, Ser-1162, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:000049815 ! epidermal growth factor receptor, signal peptide removed form (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044844
name: epidermal growth factor receptor phosphorylated form (mouse)
def: "An epidermal growth factor receptor (mouse) that includes at least one phosphorylated tyrosine. UniProtKB:Q01279, MOD:00048." [PMID:21186272, PRO:KRC]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21186272). Evidence=(ECO:0000178, based on PMID:21186272).
synonym: "mEGFR/PhosRes+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q01279, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "egfr Y-phosphorylated (mouse)" RELATED []
synonym: "erbb1 Y-phosphorylated (mouse)" RELATED []
intersection_of: has_part MOD:00048 ! O4'-phospho-L-tyrosine
intersection_of: PR:Q01279 ! epidermal growth factor receptor (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000051028
name: epidermal growth factor receptor N-glycosylated 2 (human)
def: "An epidermal growth factor receptor (human) that has been N-glycosylated at the residue equivalent to Asn-175 of the amino acid sequence represented by UniProtKB:P00533-1, in which the glycan structure is represented by GlyTouCan:G83461WR. Example: UniProtKB:P00533-1, Asn-175, MOD:00160~GNO:G83461WR." [GlyGen:P00533-1, PMID:10731668, PMID:10988252, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hEGFR/NGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-175, MOD:00160~GNO:G83461WR" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-175, MOD:00160~UniCarbKB:2921" NARROW [PRO:DNx]
is_a: PR:P00533 ! epidermal growth factor receptor (human)
relationship: has_part GNO:G83461WR ! G83461WR
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051029
name: epidermal growth factor receptor N-glycosylated 3 (human)
def: "An epidermal growth factor receptor (human) that has been N-glycosylated at the residue equivalent to Asn-352 of the amino acid sequence represented by UniProtKB:P00533-1, in which the glycan structure is represented by GlyTouCan:G83461WR. Example: UniProtKB:P00533-1, Asn-352, MOD:00160~GNO:G83461WR." [GlyGen:P00533-1, PMID:10731668, PMID:10988252, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hEGFR/NGlyco:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-352, MOD:00160~GNO:G83461WR" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-352, MOD:00160~UniCarbKB:2921" NARROW [PRO:DNx]
is_a: PR:P00533 ! epidermal growth factor receptor (human)
relationship: has_part GNO:G83461WR ! G83461WR
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000051027
name: epidermal growth factor receptor N-glycosylated 1 (human)
def: "An epidermal growth factor receptor (human) that has been N-glycosylated at the residue equivalent to Asn-128 of the amino acid sequence represented by UniProtKB:P00533-1, in which the glycan structure is represented by GlyTouCan:G83461WR. Example: UniProtKB:P00533-1, Asn-128, MOD:00160~GNO:G83461WR." [GlyGen:P00533-1, PMID:10731668, PMID:10988252, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hEGFR/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-128, MOD:00160~GNO:G83461WR" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P00533-1, Asn-128, MOD:00160~UniCarbKB:2921" NARROW [PRO:DNx]
is_a: PR:P00533 ! epidermal growth factor receptor (human)
relationship: has_part GNO:G83461WR ! G83461WR
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000027478
name: epidermal growth factor receptor isoform 1, signal peptide removed phosphorylated 1
def: "An epidermal growth factor receptor isoform 1, signal peptide removed form that is the mature receptor and has been phosphorylated by Src kinase. Example: UniProtKB:P00533-1, 25-1210, Tyr-869, MOD:00048." [PMID:18789131, PRO:DAN, PRO:PD]
comment: Category=modification.
synonym: "EGFR/iso:1/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027476 ! epidermal growth factor receptor isoform 1, signal peptide removed form
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:000027479
name: epidermal growth factor receptor isoform 1, signal peptide removed phosphorylated 1 (human)
def: "An epidermal growth factor receptor isoform 1, signal peptide removed phosphorylated 1 in human. UniProtKB:P00533-1, 25-1210, Tyr-869, MOD:00048." [PMID:18789131, PRO:PD]
comment: Category=organism-modification.
synonym: "hEGFR/iso:1/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000016665, Tyr-869, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P00533-1, 25-1210, Tyr-869, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027478 ! epidermal growth factor receptor isoform 1, signal peptide removed phosphorylated 1
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:000027476
name: epidermal growth factor receptor isoform 1, signal peptide removed form
def: "An epidermal growth factor receptor isoform 1 that has had the signal peptide removed to yield the mature receptor. Example: UniProtKB:P00533-1, 25-1210." [PMID:18789131, PRO:PD]
comment: Category=modification.
synonym: "EGFR/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000027474 ! epidermal growth factor receptor isoform 1
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000027477
name: epidermal growth factor receptor isoform 1, signal peptide removed form (human)
def: "An epidermal growth factor receptor isoform 1, signal peptide removed form in human. UniProtKB:P00533-1, 25-1210." [PMID:18789131, PRO:CNA]
comment: Category=organism-modification.
synonym: "PRO_0000016665" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hEGFR/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00533-1, 25-1210" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027476 ! epidermal growth factor receptor isoform 1, signal peptide removed form

[Term]
id: PR:000027474
name: epidermal growth factor receptor isoform 1
def: "An epidermal growth factor receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00533-1 or a 1:1 ortholog thereof." [PMID:18789131, PRO:CNA]
comment: Category=sequence.
synonym: "EGFR/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000006933 ! epidermal growth factor receptor

[Term]
id: PR:P00533-4
name: epidermal growth factor receptor isoform h4 (human)
def: "An epidermal growth factor receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00533-4." [PRO:DNx, UniProtKB:P00533]
comment: Category=organism-sequence.
synonym: "hEGFR/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P00533-4
is_a: PR:P00533 ! epidermal growth factor receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P00533-3
name: epidermal growth factor receptor isoform h3 (human)
def: "An epidermal growth factor receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00533-3." [PRO:DNx, UniProtKB:P00533]
comment: Category=organism-sequence.
synonym: "hEGFR/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "epidermal growth factor receptor isoform p110 (human)" EXACT [UniProtKB:P00533]
xref: UniProtKB:P00533-3
is_a: PR:P00533 ! epidermal growth factor receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P00533-2
name: epidermal growth factor receptor isoform h2 (human)
def: "An epidermal growth factor receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00533-2." [PRO:DNx, UniProtKB:P00533]
comment: Category=organism-sequence.
synonym: "hEGFR/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "epidermal growth factor receptor isoform p60 (human)" EXACT [UniProtKB:P00533]
synonym: "epidermal growth factor receptor isoform TEGFR (human)" EXACT [UniProtKB:P00533]
synonym: "epidermal growth factor receptor isoform Truncated (human)" EXACT [UniProtKB:P00533]
xref: UniProtKB:P00533-2
is_a: PR:P00533 ! epidermal growth factor receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P00533-1
name: epidermal growth factor receptor isoform 1 (human)
def: "An epidermal growth factor receptor isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hEGFR/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "EGFR p170 (human)" EXACT []
xref: UniProtKB:P00533-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027474 ! epidermal growth factor receptor isoform 1

[Term]
id: PR:Q01279
name: epidermal growth factor receptor (mouse)
def: "An epidermal growth factor receptor that is encoded in the genome of mouse." [OMA:Q01279, PRO:DNx]
comment: Category=organism-gene.
synonym: "Egfr" RELATED Gene-based [UniProtKB:Q01279]
synonym: "mEGFR" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q01279
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006933 ! epidermal growth factor receptor
relationship: has_gene_template MGI:95294 ! Egfr (mouse)

[Term]
id: PR:000049849
name: epidermal growth factor receptor, signal peptide removed phosphorylated 3 (human)
def: "An epidermal growth factor receptor, signal peptide removed form (human) that has been post-translationally modified to include phosphorylated serines at the C-terminal tail, at positions 1070, 1071, 1081, and 1166 of the amino acid sequence represented by UniProtKB:P00533-1. Example: UniProtKB:P00533-1, 25-1210, Ser-1070/Ser-1071/Ser-1081/Ser-1166, MOD:00046." [PMID:10347170, PRO:KER]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:10347170). Kinase=("CAMKII"; PR:000003197; Ser-1070/Ser-1071/Ser-1081/Ser-1166). Note: Ser-1166 is the major site of phosphorylation; this phosphorylation is involved in down-regulation of kinase activity.
synonym: "hEGFR/SigPep-/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00533-1, 25-1210, Ser-1070/Ser-1071/Ser-1081/Ser-1166, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:000028422 ! epidermal growth factor receptor, signal peptide removed form (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens