[Term] id: PR:000047152 name: aromatic-L-amino-acid decarboxylase pyridoxal phosphate lysine 1 (human) def: "An aromatic-L-amino-acid decarboxylase (human) that has been post-translationally modified to include pyridoxal phosphate lysine at position 303 of the amino acid sequence represented by UniProtKB:P20711. UniProtKB:P20711, Lys-303, MOD:00128." [PRO:DNx, Reactome:R-HSA-209810] comment: Category=organism-modification. synonym: "hDDC/Pyrdox:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P20711, Lys-303, MOD:00128" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-209810 "PR:000047152 located_in GO:0005829" is_a: PR:P20711 ! aromatic-L-amino-acid decarboxylase (human) relationship: has_part MOD:00128 ! N6-pyridoxal phosphate-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P05031 name: aromatic-L-amino-acid decarboxylase (fruit fly) def: "An aromatic-L-amino-acid decarboxylase that is encoded in the genome of fruit fly." [PRO:DNx] comment: Category=organism-gene. synonym: "Ddc" RELATED Gene-based [UniProtKB:P05031] synonym: "CG10697" RELATED Gene-based [UniProtKB:P05031] synonym: "fly-DDC" EXACT PRO-short-label [PRO:DNx] synonym: "DDC (fruit fly)" EXACT [UniProtKB:P05031] synonym: "AADC (fruit fly)" EXACT [UniProtKB:P05031] synonym: "DOPA decarboxylase (fruit fly)" EXACT [UniProtKB:P05031] xref: UniProtKB:P05031 intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster intersection_of: PR:000006342 ! aromatic-L-amino-acid decarboxylase relationship: has_gene_template FlyBase:FBgn0000422 ! Ddc (fruit fly) [Term] id: PR:O88533-1 name: aromatic-L-amino-acid decarboxylase isoform 1 (mouse) def: "An aromatic-L-amino-acid decarboxylase isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mDDC/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O88533-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000039031 ! aromatic-L-amino-acid decarboxylase isoform 1 [Term] id: PR:P14173 name: aromatic-L-amino-acid decarboxylase (rat) def: "An aromatic-L-amino-acid decarboxylase that is encoded in the genome of rat." [OMA:P14173, PANTHER:PTHR11999:SF11, PRO:DNx] comment: Category=organism-gene. synonym: "Ddc" RELATED Gene-based [UniProtKB:P14173] synonym: "rDDC" EXACT PRO-short-label [PRO:DNx] synonym: "DDC (rat)" EXACT [UniProtKB:P14173] synonym: "AADC (rat)" EXACT [UniProtKB:P14173] synonym: "DOPA decarboxylase (rat)" EXACT [UniProtKB:P14173] xref: UniProtKB:P14173 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000006342 ! aromatic-L-amino-acid decarboxylase relationship: has_gene_template RGD:2494 ! Ddc (rat) [Term] id: PR:P20711 name: aromatic-L-amino-acid decarboxylase (human) def: "An aromatic-L-amino-acid decarboxylase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P20711] comment: Category=organism-gene. synonym: "DDC" RELATED Gene-based [UniProtKB:P20711] synonym: "AADC" RELATED Gene-based [UniProtKB:P20711] synonym: "hDDC" EXACT PRO-short-label [PRO:DNx] synonym: "DOPA decarboxylase (human)" EXACT [UniProtKB:P20711] xref: UniProtKB:P20711 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000006342 ! aromatic-L-amino-acid decarboxylase relationship: has_gene_template HGNC:2719 ! DDC (human) [Term] id: PR:P20711-2 name: aromatic-L-amino-acid decarboxylase isoform h2 (human) def: "An aromatic-L-amino-acid decarboxylase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20711-2." [PRO:DNx, UniProtKB:P20711] comment: Category=organism-sequence. synonym: "hDDC/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "aromatic-L-amino-acid decarboxylase isoform alt-DDC (human)" EXACT [UniProtKB:P20711] xref: UniProtKB:P20711-2 is_a: PR:P20711 ! aromatic-L-amino-acid decarboxylase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O88533 name: aromatic-L-amino-acid decarboxylase (mouse) def: "An aromatic-L-amino-acid decarboxylase that is encoded in the genome of mouse." [OMA:O88533, PRO:DNx] comment: Category=organism-gene. synonym: "Ddc" RELATED Gene-based [UniProtKB:O88533] synonym: "mDDC" EXACT PRO-short-label [PRO:DNx] synonym: "DDC (mouse)" EXACT [UniProtKB:O88533] synonym: "AADC (mouse)" EXACT [UniProtKB:O88533] synonym: "DOPA decarboxylase (mouse)" EXACT [UniProtKB:O88533] xref: UniProtKB:O88533 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000006342 ! aromatic-L-amino-acid decarboxylase relationship: has_gene_template MGI:94876 ! Ddc (mouse) [Term] id: PR:000039031 name: aromatic-L-amino-acid decarboxylase isoform 1 def: "An aromatic-L-amino-acid decarboxylase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20711-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "DDC/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000006342 ! aromatic-L-amino-acid decarboxylase [Term] id: PR:P20711-3 name: aromatic-L-amino-acid decarboxylase isoform h3 (human) def: "An aromatic-L-amino-acid decarboxylase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20711-3." [PRO:DNx, UniProtKB:P20711] comment: Category=organism-sequence. synonym: "hDDC/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P20711-3 is_a: PR:P20711 ! aromatic-L-amino-acid decarboxylase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000006342 name: aromatic-L-amino-acid decarboxylase def: "A protein that is a translation product of the human DDC gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "DDC" EXACT PRO-short-label [PRO:DNx] synonym: "AADC" RELATED Gene-based [] synonym: "DOPA decarboxylase" EXACT [] xref: IUPHARobj:1271 is_a: PR:000000001 ! protein [Term] id: PR:P05031-3 name: aromatic-L-amino-acid decarboxylase isoform 3 (fruit fly) def: "An aromatic-L-amino-acid decarboxylase (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05031-3." [PRO:DNx, UniProtKB:P05031] comment: Category=organism-sequence. synonym: "fly-DDC/iso:3" EXACT PRO-short-label [PRO:DNx] synonym: "aromatic-L-amino-acid decarboxylase isoform 56.2 kDa (fruit fly)" EXACT [UniProtKB:P05031] synonym: "aromatic-L-amino-acid decarboxylase isoform Hypoderm (fruit fly)" BROAD [UniProtKB:P05031] xref: UniProtKB:P05031-3 is_a: PR:P05031 ! aromatic-L-amino-acid decarboxylase (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:P05031-2 name: aromatic-L-amino-acid decarboxylase isoform Hypoderm (fruit fly) def: "An aromatic-L-amino-acid decarboxylase (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05031-2." [PRO:DNx, UniProtKB:P05031] comment: Category=organism-sequence. synonym: "fly-DDC/iso:Hypoderm" EXACT PRO-short-label [PRO:DNx] synonym: "aromatic-L-amino-acid decarboxylase isoform B (fruit fly)" EXACT [UniProtKB:P05031] synonym: "aromatic-L-amino-acid decarboxylase isoform D (fruit fly)" EXACT [UniProtKB:P05031] synonym: "aromatic-L-amino-acid decarboxylase isoform Short (fruit fly)" EXACT [UniProtKB:P05031] xref: UniProtKB:P05031-2 is_a: PR:P05031 ! aromatic-L-amino-acid decarboxylase (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:P05031-1 name: aromatic-L-amino-acid decarboxylase isoform CNS (fruit fly) def: "An aromatic-L-amino-acid decarboxylase (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05031-1." [PRO:DNx, UniProtKB:P05031] comment: Category=organism-sequence. synonym: "fly-DDC/iso:CNS" EXACT PRO-short-label [PRO:DNx] synonym: "aromatic-L-amino-acid decarboxylase isoform C (fruit fly)" EXACT [UniProtKB:P05031] synonym: "aromatic-L-amino-acid decarboxylase isoform Long (fruit fly)" EXACT [UniProtKB:P05031] synonym: "aromatic-L-amino-acid decarboxylase isoform Brain (fruit fly)" EXACT [UniProtKB:P05031] synonym: "aromatic-L-amino-acid decarboxylase isoform 56.7 kDa (fruit fly)" EXACT [UniProtKB:P05031] xref: UniProtKB:P05031-1 is_a: PR:P05031 ! aromatic-L-amino-acid decarboxylase (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:P14173-1 name: aromatic-L-amino-acid decarboxylase isoform 1 (rat) def: "An aromatic-L-amino-acid decarboxylase isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rDDC/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P14173-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000039031 ! aromatic-L-amino-acid decarboxylase isoform 1 [Term] id: PR:P20711-1 name: aromatic-L-amino-acid decarboxylase isoform 1 (human) def: "An aromatic-L-amino-acid decarboxylase isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hDDC/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P20711-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000039031 ! aromatic-L-amino-acid decarboxylase isoform 1 [Term] id: PR:P20711-4 name: aromatic-L-amino-acid decarboxylase isoform h4 (human) def: "An aromatic-L-amino-acid decarboxylase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20711-4." [PRO:DNx, UniProtKB:P20711] comment: Category=organism-sequence. synonym: "hDDC/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P20711-4 is_a: PR:P20711 ! aromatic-L-amino-acid decarboxylase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens