[Term]
id: PR:000006154
name: cytohesin-2
def: "A protein that is a translation product of the human CYTH2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ARNO" RELATED Gene-based []
synonym: "CLM2" EXACT []
synonym: "CYTH2" EXACT PRO-short-label [PRO:DNx]
synonym: "PSCD2" RELATED Gene-based []
synonym: "Sec7b" RELATED Gene-based []
synonym: "PSCD2L" RELATED Gene-based []
synonym: "Sec7-2" EXACT []
synonym: "protein ARNO" EXACT []
synonym: "SEC7 homolog B" EXACT []
synonym: "ARF exchange factor" EXACT []
synonym: "ARF nucleotide-binding site opener" EXACT []
synonym: "PH, SEC7 and coiled-coil domain-containing protein 2" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000046033
name: cytohesin-2 phosphorylated 1 (human)
def: "A cytohesin-2 (human) that has been phosphorylated at the position equivalent to Ser-392 of the amino acid sequence represented by UniProtKB:Q99418-1. Example: UniProtKB:Q99418-1, Ser-392, MOD:00046." [PMID:10531036, iPTMnet:Q99418]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:10531036). Status=unreviewed.
synonym: "hCYTH2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q99418-1, Ser-392, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q99418 ! cytohesin-2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P63034-2
name: cytohesin-2 isoform m2 (mouse)
def: "A cytohesin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63034-2." [PRO:DNx, UniProtKB:P63034]
comment: Category=organism-sequence.
synonym: "mCYTH2/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P63034-2
is_a: PR:P63034 ! cytohesin-2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P63034-3
name: cytohesin-2 isoform m3 (mouse)
def: "A cytohesin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63034-3." [PRO:DNx, UniProtKB:P63034]
comment: Category=organism-sequence.
synonym: "mCYTH2/iso:m3" EXACT PRO-short-label [PRO:DNx]
synonym: "cytohesin-2 isoform CLM2-B (mouse)" EXACT [UniProtKB:P63034]
xref: UniProtKB:P63034-3
is_a: PR:P63034 ! cytohesin-2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P63034-1
name: cytohesin-2 isoform m1 (mouse)
def: "A cytohesin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63034-1." [PRO:DNx, UniProtKB:P63034]
comment: Category=organism-sequence.
synonym: "mCYTH2/iso:m1" EXACT PRO-short-label [PRO:DNx]
synonym: "cytohesin-2 isoform CLM2-A (mouse)" EXACT [UniProtKB:P63034]
xref: UniProtKB:P63034-1
is_a: PR:P63034 ! cytohesin-2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P34512
name: GTP exchange factor for ARFs 1 (worm)
def: "A cytohesin-2 that is encoded in the genome of worm." [PRO:DNx]
comment: Category=organism-gene.
synonym: "grp-1" RELATED Gene-based [UniProtKB:P34512]
synonym: "K06H7.4" RELATED Gene-based [UniProtKB:P34512]
synonym: "CYTH2 (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P34512
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000006154 ! cytohesin-2
relationship: has_gene_template WormBase:WBGene00001743 ! grp-1 (worm)

[Term]
id: PR:Q99418
name: cytohesin-2 (human)
def: "A cytohesin-2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99418]
comment: Category=organism-gene.
synonym: "ARNO" RELATED Gene-based [UniProtKB:Q99418]
synonym: "CYTH2" RELATED Gene-based [UniProtKB:Q99418]
synonym: "PSCD2" RELATED Gene-based [UniProtKB:Q99418]
synonym: "PSCD2L" RELATED Gene-based [UniProtKB:Q99418]
synonym: "hCYTH2" EXACT PRO-short-label [PRO:DNx]
synonym: "protein ARNO (human)" EXACT [UniProtKB:Q99418]
synonym: "ARF exchange factor (human)" EXACT [UniProtKB:Q99418]
synonym: "ARF nucleotide-binding site opener (human)" EXACT [UniProtKB:Q99418]
synonym: "PH, SEC7 and coiled-coil domain-containing protein 2 (human)" EXACT [UniProtKB:Q99418]
xref: UniProtKB:Q99418
xref: Reactome:R-HSA-8847829 "PR:Q99418 located_in GO:0000139"
xref: Reactome:R-HSA-8847831 "PR:Q99418 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006154 ! cytohesin-2
relationship: has_gene_template HGNC:9502 ! CYTH2 (human)

[Term]
id: PR:P63035
name: cytohesin-2 (rat)
def: "A cytohesin-2 that is encoded in the genome of rat." [OMA:P63035, PANTHER:PTHR10663:SF58, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cyth2" RELATED Gene-based [UniProtKB:P63035]
synonym: "Pscd2" RELATED Gene-based [UniProtKB:P63035]
synonym: "Sec7b" RELATED Gene-based [UniProtKB:P63035]
synonym: "rCYTH2" EXACT PRO-short-label [PRO:DNx]
synonym: "CLM2 (rat)" EXACT [UniProtKB:P63035]
synonym: "protein ARNO (rat)" EXACT [UniProtKB:P63035]
synonym: "SEC7 homolog B (rat)" EXACT [UniProtKB:P63035]
synonym: "ARF nucleotide-binding site opener (rat)" EXACT [UniProtKB:P63035]
synonym: "PH, SEC7 and coiled-coil domain-containing protein 2 (rat)" EXACT [UniProtKB:P63035]
xref: UniProtKB:P63035
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006154 ! cytohesin-2
relationship: has_gene_template RGD:620398 ! Cyth2 (rat)

[Term]
id: PR:P63034
name: cytohesin-2 (mouse)
def: "A cytohesin-2 that is encoded in the genome of mouse." [OMA:P63034, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cyth2" RELATED Gene-based [UniProtKB:P63034]
synonym: "Pscd2" RELATED Gene-based [UniProtKB:P63034]
synonym: "Sec7b" RELATED Gene-based [UniProtKB:P63034]
synonym: "mCYTH2" EXACT PRO-short-label [PRO:DNx]
synonym: "mSec7-2" EXACT [UniProtKB:P63034]
synonym: "CLM2 (mouse)" EXACT [UniProtKB:P63034]
synonym: "protein ARNO (mouse)" EXACT [UniProtKB:P63034]
synonym: "SEC7 homolog B (mouse)" EXACT [UniProtKB:P63034]
synonym: "ARF nucleotide-binding site opener (mouse)" EXACT [UniProtKB:P63034]
synonym: "PH, SEC7 and coiled-coil domain-containing protein 2 (mouse)" EXACT [UniProtKB:P63034]
xref: UniProtKB:P63034
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006154 ! cytohesin-2
relationship: has_gene_template MGI:1334255 ! Cyth2 (mouse)

[Term]
id: PR:000042697
name: cytohesin-2 isoform 1
def: "A cytohesin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99418-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "CYTH2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000006154 ! cytohesin-2

[Term]
id: PR:P63035-1
name: cytohesin-2 isoform 1 (rat)
def: "A cytohesin-2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rCYTH2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P63035-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000042697 ! cytohesin-2 isoform 1

[Term]
id: PR:Q99418-2
name: cytohesin-2 isoform h2 (human)
def: "A cytohesin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99418-2." [PRO:DNx, UniProtKB:Q99418]
comment: Category=organism-sequence.
synonym: "hCYTH2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99418-2
is_a: PR:Q99418 ! cytohesin-2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q99418-1
name: cytohesin-2 isoform 1 (human)
def: "A cytohesin-2 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hCYTH2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99418-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000042697 ! cytohesin-2 isoform 1