[Term]
id: PR:000006121
name: cytochrome P450 2D6
def: "A protein that is a translation product of the human CYP2D6 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CYP2D6" EXACT PRO-short-label [PRO:DNx]
synonym: "CYP2DL1" RELATED Gene-based []
synonym: "CYPIID6" EXACT []
synonym: "cytochrome P450-DB1" EXACT []
synonym: "debrisoquine 4-hydroxylase" EXACT []
xref: IUPHARobj:1329
is_a: PR:000000001 ! protein

[Term]
id: PR:P10635
name: cytochrome P450 2D6 (human)
def: "A cytochrome P450 2D6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P10635]
comment: Category=organism-gene.
synonym: "CYP2D6" RELATED Gene-based [UniProtKB:P10635]
synonym: "CYP2DL1" RELATED Gene-based [UniProtKB:P10635]
synonym: "hCYP2D6" EXACT PRO-short-label [PRO:DNx]
synonym: "CYPIID6 (human)" EXACT [UniProtKB:P10635]
synonym: "cytochrome P450-DB1 (human)" EXACT [UniProtKB:P10635]
synonym: "cholesterol 25-hydroxylase (human)" BROAD [UniProtKB:P10635]
synonym: "debrisoquine 4-hydroxylase (human)" EXACT [UniProtKB:P10635]
xref: Reactome:R-HSA-52679 "PR:P10635 located_in GO:0005789"
xref: UniProtKB:P10635
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006121 ! cytochrome P450 2D6
relationship: has_gene_template HGNC:2625 ! CYP2D6 (human)

[Term]
id: PR:Q64680
name: cytochrome P450 2D4 (rat)
def: "A cytochrome P450 2D6 that is encoded in the genome of rat." [PANTHER:PTHR24300:SF72, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cyp2d4" RELATED Gene-based [UniProtKB:Q64680]
synonym: "Cyp2d-4" RELATED Gene-based [UniProtKB:Q64680]
synonym: "Cyp2d18" RELATED Gene-based [UniProtKB:Q64680]
synonym: "rCYP2D6" EXACT PRO-short-label [PRO:DNx]
synonym: "Cyp2d-18" RELATED Gene-based [UniProtKB:Q64680]
synonym: "CYPIID4 (rat)" EXACT [UniProtKB:Q64680]
synonym: "CYPIID18 (rat)" EXACT [UniProtKB:Q64680]
synonym: "cytochrome P450-DB4 (rat)" EXACT [UniProtKB:Q64680]
synonym: "cytochrome P450 2D18 (rat)" EXACT [UniProtKB:Q64680]
synonym: "cytochrome P450-CMF3 (rat)" EXACT [UniProtKB:Q64680]
synonym: "cytochrome P450 2D-29 (rat)" EXACT [UniProtKB:Q64680]
synonym: "cytochrome P450 2D-35 (rat)" EXACT [UniProtKB:Q64680]
synonym: "debrisoquine 4-hydroxylase (rat)" BROAD [UniProtKB:Q64680]
xref: UniProtKB:Q64680
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006121 ! cytochrome P450 2D6
relationship: has_gene_template RGD:620640 ! Cyp2d4 (rat)

[Term]
id: PR:P10635-2
name: cytochrome P450 2D6 isoform h2 (human)
def: "A cytochrome P450 2D6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10635-2." [PRO:DNx, UniProtKB:P10635]
comment: Category=organism-sequence.
synonym: "hCYP2D6/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10635-2
is_a: PR:P10635 ! cytochrome P450 2D6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P10635-1
name: cytochrome P450 2D6 isoform h1 (human)
def: "A cytochrome P450 2D6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10635-1." [PRO:DNx, UniProtKB:P10635]
comment: Category=organism-sequence.
synonym: "hCYP2D6/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10635-1
is_a: PR:P10635 ! cytochrome P450 2D6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens