[Term]
id: PR:P04839
name: cytochrome b-245 heavy chain (human)
def: "A cytochrome b-245 heavy chain that is encoded in the genome of human." [PRO:DNx, UniProtKB:P04839]
comment: Category=organism-gene.
synonym: "CYBB" RELATED Gene-based [UniProtKB:P04839]
synonym: "NOX2" RELATED Gene-based [UniProtKB:P04839]
synonym: "hCYBB" EXACT PRO-short-label [PRO:DNx]
synonym: "gp91-1 (human)" EXACT [UniProtKB:P04839]
synonym: "gp91-phox (human)" EXACT [UniProtKB:P04839]
synonym: "CGD91-phox (human)" EXACT [UniProtKB:P04839]
synonym: "NADPH oxidase 2 (human)" EXACT [UniProtKB:P04839]
synonym: "p22 phagocyte B-cytochrome (human)" BROAD [UniProtKB:P04839]
synonym: "cytochrome b558 subunit beta (human)" EXACT [UniProtKB:P04839]
synonym: "cytochrome b(558) subunit beta (human)" EXACT [UniProtKB:P04839]
synonym: "neutrophil cytochrome b 91 kDa polypeptide (human)" EXACT [UniProtKB:P04839]
synonym: "heme-binding membrane glycoprotein gp91phox (human)" EXACT [UniProtKB:P04839]
synonym: "superoxide-generating NADPH oxidase heavy chain subunit (human)" EXACT [UniProtKB:P04839]
xref: DTO:01100097
xref: UniProtKB:P04839
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006087 ! cytochrome b-245 heavy chain
relationship: has_gene_template HGNC:2578 ! CYBB (human)

[Term]
id: PR:P04839-1
name: cytochrome b-245 heavy chain isoform 1 (human)
def: "A cytochrome b-245 heavy chain isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hCYBB/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P04839-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038658 ! cytochrome b-245 heavy chain isoform 1

[Term]
id: PR:000038658
name: cytochrome b-245 heavy chain isoform 1
def: "A cytochrome b-245 heavy chain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04839-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "CYBB/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000006087 ! cytochrome b-245 heavy chain

[Term]
id: PR:000047119
name: cytochrome b-245 heavy chain, initiator methionine removed form (human)
def: "A cytochrome b-245 heavy chain (human) that has had the initiator methionine removed. UniProtKB:P04839, 2-570." [PRO:DNx, Reactome:R-HSA-1222445, Reactome:R-HSA-5218720, Reactome:R-HSA-6809195]
comment: Category=organism-modification.
synonym: "PRO_0000210145" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hCYBB/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P04839, 2-570" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1222445 "PR:000047119 located_in GO:0030670"
xref: Reactome:R-HSA-5218720 "PR:000047119 located_in GO:0005886"
xref: Reactome:R-HSA-6799568 "PR:000047119 located_in GO:0035579"
xref: Reactome:R-HSA-6801012 "PR:000047119 located_in GO:0070821"
xref: Reactome:R-HSA-6809195 "PR:000047119 located_in GO:0005789"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P04839 ! cytochrome b-245 heavy chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q61093
name: cytochrome b-245 heavy chain (mouse)
def: "A cytochrome b-245 heavy chain that is encoded in the genome of mouse." [OMA:Q61093, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cgd" RELATED Gene-based [UniProtKB:Q61093]
synonym: "Cybb" RELATED Gene-based [UniProtKB:Q61093]
synonym: "mCYBB" EXACT PRO-short-label [PRO:DNx]
synonym: "gp91-1 (mouse)" EXACT [UniProtKB:Q61093]
synonym: "gp91-phox (mouse)" EXACT [UniProtKB:Q61093]
synonym: "CGD91-phox (mouse)" EXACT [UniProtKB:Q61093]
synonym: "p22 phagocyte B-cytochrome (mouse)" RELATED [UniProtKB:Q61093]
synonym: "cytochrome b558 subunit beta (mouse)" EXACT [UniProtKB:Q61093]
synonym: "cytochrome b(558) subunit beta (mouse)" EXACT [UniProtKB:Q61093]
synonym: "neutrophil cytochrome b 91 kDa polypeptide (mouse)" EXACT [UniProtKB:Q61093]
synonym: "heme-binding membrane glycoprotein gp91phox (mouse)" EXACT [UniProtKB:Q61093]
xref: UniProtKB:Q61093
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006087 ! cytochrome b-245 heavy chain
relationship: has_gene_template MGI:88574 ! Cybb (mouse)

[Term]
id: PR:Q61093-1
name: cytochrome b-245 heavy chain isoform 1 (mouse)
def: "A cytochrome b-245 heavy chain isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mCYBB/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q61093-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038658 ! cytochrome b-245 heavy chain isoform 1

[Term]
id: PR:000019611
name: cytochrome b-245 heavy chain, initiator methionine removed form
def: "A cytochrome b-245 heavy chain that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "CYBB/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000006087 ! cytochrome b-245 heavy chain
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000006087
name: cytochrome b-245 heavy chain
def: "A protein that is a translation product of the human CYBB gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Cgd" RELATED Gene-based []
synonym: "CYBB" EXACT PRO-short-label [PRO:DNx]
synonym: "NOX2" RELATED Gene-based []
synonym: "gp91-1" EXACT []
synonym: "gp91-phox" EXACT []
synonym: "CGD91-phox" EXACT []
synonym: "NADPH oxidase 2" EXACT []
synonym: "p22 phagocyte B-cytochrome" RELATED []
synonym: "cytochrome b558 subunit beta" EXACT []
synonym: "cytochrome b(558) subunit beta" EXACT []
synonym: "neutrophil cytochrome b 91 kDa polypeptide" EXACT []
synonym: "heme-binding membrane glycoprotein gp91phox" EXACT []
synonym: "superoxide-generating NADPH oxidase heavy chain subunit" EXACT []
is_a: PR:000000001 ! protein