[Term] id: PR:P10619-1 name: lysosomal protective protein isoform h1 (human) def: "A lysosomal protective protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10619-1." [PRO:DNx, UniProtKB:P10619] comment: Category=organism-sequence. synonym: "hCTSA/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P10619-1 is_a: PR:P10619 ! lysosomal protective protein (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O60123 name: pheromone-processing carboxypeptidase kex1 (Schizosaccharomyces pombe 972h-) def: "A lysosomal protective protein that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:DNx] comment: Category=organism-gene. synonym: "kex1" RELATED Gene-based [UniProtKB:O60123] synonym: "SPBC16G5.09" RELATED Gene-based [UniProtKB:O60123] synonym: "Spom972h-CTSA" EXACT PRO-short-label [PRO:DNx] synonym: "carboxypeptidase D (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O60123] xref: UniProtKB:O60123 intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h- intersection_of: PR:000006022 ! lysosomal protective protein relationship: has_gene_template PomBase:SPBC16G5.09 ! kex1 (Schizosaccharomyces pombe) [Term] id: PR:P10619-2 name: lysosomal protective protein isoform h2 (human) def: "A lysosomal protective protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10619-2." [PRO:DNx, UniProtKB:P10619] comment: Category=organism-sequence. synonym: "hCTSA/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P10619-2 is_a: PR:P10619 ! lysosomal protective protein (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P16675 name: lysosomal protective protein (mouse) def: "A lysosomal protective protein that is encoded in the genome of mouse." [OMA:P16675, PRO:DNx] comment: Category=organism-gene. Requested by=PubChem. synonym: "Ctsa" RELATED Gene-based [UniProtKB:P16675] synonym: "Ppgb" RELATED Gene-based [UniProtKB:P16675] synonym: "mCTSA" EXACT PRO-short-label [PRO:DNx] synonym: "PPCA (mouse)" EXACT [UniProtKB:P16675] synonym: "cathepsin A (mouse)" EXACT [UniProtKB:P16675] synonym: "carboxypeptidase C (mouse)" EXACT [UniProtKB:P16675] synonym: "carboxypeptidase L (mouse)" EXACT [UniProtKB:P16675] synonym: "protective protein cathepsin A (mouse)" EXACT [UniProtKB:P16675] synonym: "protective protein for beta-galactosidase (mouse)" EXACT [UniProtKB:P16675] xref: UniProtKB:P16675 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000006022 ! lysosomal protective protein relationship: has_gene_template MGI:97748 ! Ctsa (mouse) [Term] id: PR:000006022 name: lysosomal protective protein def: "A protein that is a translation product of the human CTSA gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "CTSA" EXACT PRO-short-label [PRO:DNx] synonym: "PPCA" EXACT [] synonym: "PPGB" RELATED Gene-based [] synonym: "cathepsin A" EXACT [] synonym: "carboxypeptidase C" EXACT [] synonym: "carboxypeptidase L" EXACT [] synonym: "protective protein cathepsin A" EXACT [] synonym: "protective protein for beta-galactosidase" EXACT [] xref: IUPHARobj:1581 is_a: PR:000000001 ! protein [Term] id: PR:000047099 name: lysosomal protective protein, signal peptide removed form (human) def: "A lysosomal protective protein (human) that has had the signal peptide removed. UniProtKB:P10619, 29-480." [PRO:DNx, Reactome:R-HSA-1181230] comment: Category=organism-modification. synonym: "hCTSA/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000004274" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P10619, 29-480" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-1181230 "PR:000047099 located_in GO:0043202" intersection_of: PR:P10619 ! lysosomal protective protein (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000019554 name: lysosomal protective protein proteolytic cleavage product def: "A lysosomal protective protein that has been processed by proteolytic cleavage." [PRO:DNx] comment: Category=modification. synonym: "CTSA/ClvPrd" EXACT PRO-short-label [PRO:DNx] intersection_of: output_of GO:0016485 ! protein processing intersection_of: PR:000006022 ! lysosomal protective protein [Term] id: PR:Q54DY7 name: serine carboxypeptidase S10 family member 1 (Dictyostelium discoideum) def: "A lysosomal protective protein that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54DY7, PRO:DNx] comment: Category=organism-gene. synonym: "Dicty-CTSA" EXACT PRO-short-label [PRO:DNx] synonym: "DDB_G0291912" RELATED Gene-based [UniProtKB:Q54DY7] xref: UniProtKB:Q54DY7 intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum intersection_of: PR:000006022 ! lysosomal protective protein relationship: has_gene_template dictyBase:DDB_G0291912 ! DDB_G0291912 (Dictyostelium discoideum) [Term] id: PR:000019553 name: lysosomal protective protein, signal peptide removed form def: "A lysosomal protective protein that has had the signal peptide removed." [PRO:DNx] comment: Category=modification. synonym: "CTSA/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000006022 ! lysosomal protective protein intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:P10619 name: lysosomal protective protein (human) def: "A lysosomal protective protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:P10619] comment: Category=organism-gene. synonym: "CTSA" RELATED Gene-based [UniProtKB:P10619] synonym: "PPGB" RELATED Gene-based [UniProtKB:P10619] synonym: "hCTSA" EXACT PRO-short-label [PRO:DNx] synonym: "PPCA (human)" EXACT [UniProtKB:P10619] synonym: "cathepsin A (human)" EXACT [UniProtKB:P10619] synonym: "carboxypeptidase C (human)" EXACT [UniProtKB:P10619] synonym: "carboxypeptidase L (human)" EXACT [UniProtKB:P10619] synonym: "protective protein cathepsin A (human)" EXACT [UniProtKB:P10619] synonym: "protective protein for beta-galactosidase (human)" EXACT [UniProtKB:P10619] xref: UniProtKB:P10619 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000006022 ! lysosomal protective protein relationship: has_gene_template HGNC:9251 ! CTSA (human)