[Term]
id: PR:000025999
name: catechol O-methyltransferase isoform 2
def: "A catechol O-methyltransferase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88587-2 or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=sequence.
synonym: "COMT/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000005731 ! catechol O-methyltransferase

[Term]
id: PR:O88587-1
name: catechol O-methyltransferase isoform 1 (mouse)
def: "A catechol O-methyltransferase isoform 1 that is encoded in the genome of mouse." [PMID:20374420, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mCOMT/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "MB-COMT (mouse)" EXACT []
synonym: "membrane bound COMT" EXACT []
xref: UniProtKB:O88587-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000025997 ! catechol O-methyltransferase isoform 1

[Term]
id: PR:F4ZGF2
name: catechol O-methyltransferase A (zebrafish)
def: "A catechol O-methyltransferase that is encoded in the genome of zebrafish." [PRO:DNx]
comment: Category=organism-gene.
synonym: "comta" RELATED Gene-based [UniProtKB:F4ZGF2]
synonym: "z-COMT" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:F4ZGF2
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000005731 ! catechol O-methyltransferase
relationship: has_gene_template ZFIN:ZDB-GENE-050913-117 ! comta (zebrafish)

[Term]
id: PR:P21964
name: catechol O-methyltransferase (human)
def: "A catechol O-methyltransferase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P21964]
comment: Category=organism-gene.
synonym: "COMT" RELATED Gene-based [UniProtKB:P21964]
synonym: "hCOMT" EXACT PRO-short-label [PRO:DNx]
xref: Reactome:R-HSA-175974 "PR:P21964 located_in GO:0005829"
xref: Reactome:R-HSA-379386 "PR:P21964 located_in GO:0005886"
xref: UniProtKB:P21964
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005731 ! catechol O-methyltransferase
relationship: has_gene_template HGNC:2228 ! COMT (human)

[Term]
id: PR:000005731
name: catechol O-methyltransferase
def: "A protein that is a translation product of the human COMT gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "COMT" EXACT PRO-short-label [PRO:DNx]
synonym: "Comt1" RELATED Gene-based []
xref: IUPHARobj:2472
is_a: PR:000000001 ! protein

[Term]
id: PR:P21964-2
name: catechol O-methyltransferase isoform Soluble (human)
def: "A catechol O-methyltransferase isoform 2 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hCOMT/iso:Soluble" EXACT PRO-short-label [PRO:DNx]
synonym: "catechol O-methyltransferase isoform S-COMT (human)" EXACT [UniProtKB:P21964]
xref: UniProtKB:P21964-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025999 ! catechol O-methyltransferase isoform 2

[Term]
id: PR:P22734
name: catechol O-methyltransferase (rat)
def: "A catechol O-methyltransferase that is encoded in the genome of rat." [OMA:P22734, PANTHER:PTHR10509:SF2, PRO:DNx]
comment: Category=organism-gene.
synonym: "Comt" RELATED Gene-based [UniProtKB:P22734]
synonym: "rCOMT" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P22734
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000005731 ! catechol O-methyltransferase
relationship: has_gene_template RGD:2379 ! Comt (rat)

[Term]
id: PR:000025997
name: catechol O-methyltransferase isoform 1
def: "A catechol O-methyltransferase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88587-1 or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=sequence.
synonym: "COMT/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000005731 ! catechol O-methyltransferase

[Term]
id: PR:O42898
name: probable catechol O-methyltransferase 1 (Schizosaccharomyces pombe 972h-)
def: "A catechol O-methyltransferase that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O42898, PRO:DNx]
comment: Category=organism-gene.
synonym: "SPBC119.03" RELATED Gene-based [UniProtKB:O42898]
synonym: "Spom972h-COMT" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O42898
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000005731 ! catechol O-methyltransferase
relationship: has_gene_template PomBase:SPBC119.03 ! SPBC119.03 (Schizosaccharomyces pombe)

[Term]
id: PR:P21964-1
name: catechol O-methyltransferase isoform Membrane-bound (human)
def: "A catechol O-methyltransferase isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hCOMT/iso:Membrane-bound" EXACT PRO-short-label [PRO:DNx]
synonym: "catechol O-methyltransferase isoform MB-COMT (human)" EXACT [UniProtKB:P21964]
xref: UniProtKB:P21964-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025997 ! catechol O-methyltransferase isoform 1

[Term]
id: PR:P22734-2
name: catechol O-methyltransferase isoform Soluble (rat)
def: "A catechol O-methyltransferase (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22734-2." [PRO:DNx, UniProtKB:P22734]
comment: Category=organism-sequence.
synonym: "rCOMT/iso:Soluble" EXACT PRO-short-label [PRO:DNx]
synonym: "catechol O-methyltransferase isoform S-COMT (rat)" EXACT [UniProtKB:P22734]
xref: UniProtKB:P22734-2
is_a: PR:P22734 ! catechol O-methyltransferase (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:F4ZGF2-2
name: catechol O-methyltransferase A isoform 2 (zebrafish)
def: "A catechol O-methyltransferase A (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:F4ZGF2-2." [PRO:DNx, UniProtKB:F4ZGF2]
comment: Category=organism-sequence.
synonym: "z-COMT/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:F4ZGF2-2
is_a: PR:F4ZGF2 ! catechol O-methyltransferase A (zebrafish)
relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio

[Term]
id: PR:F4ZGF2-1
name: catechol O-methyltransferase A isoform 1 (zebrafish)
def: "A catechol O-methyltransferase A (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:F4ZGF2-1." [PRO:DNx, UniProtKB:F4ZGF2]
comment: Category=organism-sequence.
synonym: "z-COMT/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:F4ZGF2-1
is_a: PR:F4ZGF2 ! catechol O-methyltransferase A (zebrafish)
relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio

[Term]
id: PR:P22734-1
name: catechol O-methyltransferase isoform Membrane-bound (rat)
def: "A catechol O-methyltransferase (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22734-1." [PRO:DNx, UniProtKB:P22734]
comment: Category=organism-sequence.
synonym: "rCOMT/iso:Membrane-bound" EXACT PRO-short-label [PRO:DNx]
synonym: "catechol O-methyltransferase isoform MB-COMT (rat)" EXACT [UniProtKB:P22734]
xref: UniProtKB:P22734-1
is_a: PR:P22734 ! catechol O-methyltransferase (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:O88587
name: catechol O-methyltransferase (mouse)
def: "A catechol O-methyltransferase that is encoded in the genome of mouse." [OMA:O88587, PRO:DNx]
comment: Category=organism-gene.
synonym: "Comt" RELATED Gene-based [UniProtKB:O88587]
synonym: "Comt1" RELATED Gene-based [UniProtKB:O88587]
synonym: "mCOMT" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O88587
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000005731 ! catechol O-methyltransferase
relationship: has_gene_template MGI:88470 ! Comt (mouse)

[Term]
id: PR:O88587-2
name: catechol O-methyltransferase isoform 2 (mouse)
def: "A catechol O-methyltransferase isoform 2 that is encoded in the genome of mouse." [PMID:20374420, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mCOMT/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "s-COMT (mouse)" EXACT []
synonym: "soluble COMT (mouse)" EXACT []
xref: UniProtKB:O88587-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000025999 ! catechol O-methyltransferase isoform 2