[Term]
id: PR:P51790-4
name: H(+)/Cl(-) exchange transporter 3 isoform h3 (human)
def: "An H(+)/Cl(-) exchange transporter 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51790-4." [PRO:DNx, UniProtKB:P51790]
comment: Category=organism-sequence.
synonym: "hCLCN3/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P51790-4
is_a: PR:P51790 ! H(+)/Cl(-) exchange transporter 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P51790-5
name: H(+)/Cl(-) exchange transporter 3 isoform h4 (human)
def: "An H(+)/Cl(-) exchange transporter 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51790-5." [PRO:DNx, UniProtKB:P51790]
comment: Category=organism-sequence.
synonym: "hCLCN3/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P51790-5
is_a: PR:P51790 ! H(+)/Cl(-) exchange transporter 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P51790-2
name: H(+)/Cl(-) exchange transporter 3 isoform h2 (human)
def: "An H(+)/Cl(-) exchange transporter 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51790-2." [PRO:DNx, UniProtKB:P51790]
comment: Category=organism-sequence.
synonym: "hCLCN3/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "H(+)/Cl(-) exchange transporter 3 isoform ClC-3B (human)" EXACT [UniProtKB:P51790]
xref: UniProtKB:P51790-2
is_a: PR:P51790 ! H(+)/Cl(-) exchange transporter 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P51790-1
name: H(+)/Cl(-) exchange transporter 3 isoform 1 (human)
def: "An H(+)/Cl(-) exchange transporter 3 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hCLCN3/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "H(+)/Cl(-) exchange transporter 3 isoform ClC-3A (human)" EXACT [UniProtKB:P51790]
xref: UniProtKB:P51790-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039679 ! H(+)/Cl(-) exchange transporter 3 isoform 1

[Term]
id: PR:000005530
name: H(+)/Cl(-) exchange transporter 3
def: "A CIC family protein that is a translation product of the human CLCN3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Clc3" RELATED Gene-based []
synonym: "CLCN3" EXACT PRO-short-label [PRO:DNx]
synonym: "ClC-3" EXACT []
synonym: "chloride channel protein 3" EXACT []
synonym: "chloride transporter ClC-3" EXACT []
xref: IUPHARobj:702
is_a: PR:000044673 ! CIC family protein

[Term]
id: PR:P51790
name: H(+)/Cl(-) exchange transporter 3 (human)
def: "An H(+)/Cl(-) exchange transporter 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P51790]
comment: Category=organism-gene.
synonym: "CLCN3" RELATED Gene-based [UniProtKB:P51790]
synonym: "hCLCN3" EXACT PRO-short-label [PRO:DNx]
synonym: "ClC-3 (human)" EXACT [UniProtKB:P51790]
synonym: "chloride channel protein 3 (human)" EXACT [UniProtKB:P51790]
synonym: "chloride transporter ClC-3 (human)" EXACT [UniProtKB:P51790]
xref: Reactome:R-HSA-2671918 "PR:P51790 located_in GO:0031902"
xref: DTO:01100074
xref: UniProtKB:P51790
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005530 ! H(+)/Cl(-) exchange transporter 3
relationship: has_gene_template HGNC:2021 ! CLCN3 (human)

[Term]
id: PR:000045819
name: H(+)/Cl(-) exchange transporter 3 phosphorylated 1 (human)
def: "An H(+)/Cl(-) exchange transporter 3 (human) that has been phosphorylated at the position equivalent to Ser-109 of the amino acid sequence represented by UniProtKB:P51790-1. Example: UniProtKB:P51790-1, Ser-109, MOD:00046." [PMID:14754994, iPTMnet:P51790]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:14754994). Status=unreviewed.
synonym: "hCLCN3/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P51790-1, Ser-109, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P51790 ! H(+)/Cl(-) exchange transporter 3 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens