[Term]
id: PR:000005418
name: serine/threonine-protein kinase Chk2
def: "A protein that is a translation product of the human CHEK2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CDS1" RELATED Gene-based []
synonym: "CHK2" RELATED Gene-based []
synonym: "cds1" EXACT []
synonym: "CHEK2" EXACT PRO-short-label [PRO:DNx]
synonym: "RAD53" RELATED Gene-based []
synonym: "checkpoint kinase 2" EXACT []
synonym: "CHK2 checkpoint homolog" EXACT []
xref: IUPHARobj:1988
is_a: PR:000000001 ! protein

[Term]
id: PR:000030002
name: serine/threonine-protein kinase cds1 (Schizosaccharomyces pombe)
def: "A serine/threonine-protein kinase Chk2 that is encoded in the genome of Schizosaccharomyces pombe." [PRO:DAN]
comment: Category=organism-gene.
synonym: "Spom-cds1" EXACT PRO-short-label [PRO:DAN]
intersection_of: only_in_taxon NCBITaxon:4896 ! Schizosaccharomyces pombe
intersection_of: PR:000005418 ! serine/threonine-protein kinase Chk2
relationship: has_gene_template PomBase:SPCC18B5.11c ! cds1 (Schizosaccharomyces pombe)

[Term]
id: PR:000037297
name: serine/threonine-protein kinase cds1 phosphorylated 2 (Schizosaccharomyces pombe)
def: "A serine/threonine-protein kinase cds1 (Schizosaccharomyces pombe) that has been phosphorylated on the Thr residue in the second TQ motif by rad3, and further phosphorylated a second Thr within the activation loop by autocatalysis. Example: UniProtKB:Q09170, Thr-11/Thr-328, MOD:00047." [PMID:19357077, PomBase:AL]
comment: Category=organism-modification. Kinase=("cds1"; PR:Q09170). Kinase=("rad3"; PR:Q02099).
synonym: "cds1 T328-P" RELATED []
synonym: "Spom-cds1/Phos:2" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:Q09170, Thr-11/Thr-328, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:000030002 ! serine/threonine-protein kinase cds1 (Schizosaccharomyces pombe)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:4896 ! Schizosaccharomyces pombe

[Term]
id: PR:000037296
name: serine/threonine-protein kinase cds1 phosphorylated 1 (Schizosaccharomyces pombe)
def: "A serine/threonine-protein kinase cds1 (Schizosaccharomyces pombe) that has been phosphorylated on the Thr residue in the second TQ motif by rad3. Example: UniProtKB:Q09170, Thr-11, MOD:00047." [PMID:15173168, PomBase:AL]
comment: Category=organism-modification. Kinase=("rad3"; PR:Q02099).
synonym: "Spom-cds1/Phos:1" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:Q09170, Thr-11, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:000030002 ! serine/threonine-protein kinase cds1 (Schizosaccharomyces pombe)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:4896 ! Schizosaccharomyces pombe