[Term]
id: PR:Q8N5S9-1
name: calcium/calmodulin-dependent protein kinase kinase 1 isoform 1 (human)
def: "A calcium/calmodulin-dependent protein kinase kinase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hCAMKK1/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "calcium/calmodulin-dependent protein kinase kinase 1 isoform A (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "calcium/calmodulin-dependent protein kinase kinase 1 isoform Variant 3 (human)" EXACT [UniProtKB:Q8N5S9]
xref: UniProtKB:Q8N5S9-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000041866 ! calcium/calmodulin-dependent protein kinase kinase 1 isoform 1

[Term]
id: PR:Q8N5S9-2
name: calcium/calmodulin-dependent protein kinase kinase 1 isoform h2 (human)
def: "A calcium/calmodulin-dependent protein kinase kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N5S9-2." [PRO:DNx, UniProtKB:Q8N5S9]
comment: Category=organism-sequence.
synonym: "hCAMKK1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "calcium/calmodulin-dependent protein kinase kinase 1 isoform B (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "calcium/calmodulin-dependent protein kinase kinase 1 isoform Variant 1 (human)" EXACT [UniProtKB:Q8N5S9]
xref: UniProtKB:Q8N5S9-2
is_a: PR:Q8N5S9 ! calcium/calmodulin-dependent protein kinase kinase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046560
name: calcium/calmodulin-dependent protein kinase kinase 1 phosphorylated form (human)
def: "A calcium/calmodulin-dependent protein kinase kinase 1 (human) that includes at least one phosphorylated residue. UniProtKB:Q8N5S9, MOD:00696." [PRO:DNx, Reactome:R-HSA-444232]
comment: Category=organism-modification.
synonym: "hCAMKK1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8N5S9, MOD:00696" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-444232 "PR:000046560 located_in GO:0005829"
xref: Reactome:R-HSA-9619356 "PR:000046560 located_in GO:0005829"
intersection_of: has_part MOD:00696 ! phosphorylated residue
intersection_of: PR:Q8N5S9 ! calcium/calmodulin-dependent protein kinase kinase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000004994
name: calcium/calmodulin-dependent protein kinase kinase 1
def: "A protein that is a translation product of the human CAMKK1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Camkk" RELATED Gene-based []
synonym: "CAMKK1" EXACT PRO-short-label [PRO:DNx]
synonym: "CAMKKA" RELATED Gene-based []
synonym: "CaMKK 1" EXACT []
synonym: "CaM-KK 1" EXACT []
synonym: "CaMKK alpha" EXACT []
synonym: "CaM-KK alpha" EXACT []
synonym: "CaM-kinase kinase 1" EXACT []
synonym: "CaM-kinase IV kinase" EXACT []
synonym: "CaM-kinase kinase alpha" EXACT []
synonym: "calcium/calmodulin-dependent protein kinase kinase alpha" EXACT []
xref: IUPHARobj:1956
is_a: PR:000000001 ! protein

[Term]
id: PR:Q8N5S9
name: calcium/calmodulin-dependent protein kinase kinase 1 (human)
def: "A calcium/calmodulin-dependent protein kinase kinase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8N5S9]
comment: Category=organism-gene.
synonym: "CAMKK1" RELATED Gene-based [UniProtKB:Q8N5S9]
synonym: "CAMKKA" RELATED Gene-based [UniProtKB:Q8N5S9]
synonym: "hCAMKK1" EXACT PRO-short-label [PRO:DNx]
synonym: "CaMKK 1 (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "CaM-KK 1 (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "CaMKK alpha (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "CaM-KK alpha (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "CaM-kinase kinase 1 (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "CaM-kinase IV kinase (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "CaM-kinase kinase alpha (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "calcium/calmodulin-dependent protein kinase kinase alpha (human)" EXACT [UniProtKB:Q8N5S9]
xref: UniProtKB:Q8N5S9
xref: Reactome:R-HSA-442775 "PR:Q8N5S9 located_in GO:0005829"
xref: Reactome:R-HSA-9619232 "PR:Q8N5S9 located_in GO:0005829"
xref: DTO:03100232
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004994 ! calcium/calmodulin-dependent protein kinase kinase 1
relationship: has_gene_template HGNC:1469 ! CAMKK1 (human)