[Term]
id: PR:Q8VBY2
name: calcium/calmodulin-dependent protein kinase kinase 1 (mouse)
def: "A calcium/calmodulin-dependent protein kinase kinase 1 that is encoded in the genome of mouse." [OMA:Q8VBY2, PRO:DNx]
comment: Category=organism-gene.
synonym: "Camkk" RELATED Gene-based [UniProtKB:Q8VBY2]
synonym: "Camkk1" RELATED Gene-based [UniProtKB:Q8VBY2]
synonym: "mCAMKK1" EXACT PRO-short-label [PRO:DNx]
synonym: "CaMKK 1 (mouse)" EXACT [UniProtKB:Q8VBY2]
synonym: "CaM-KK 1 (mouse)" EXACT [UniProtKB:Q8VBY2]
synonym: "CaMKK alpha (mouse)" EXACT [UniProtKB:Q8VBY2]
synonym: "CaM-KK alpha (mouse)" EXACT [UniProtKB:Q8VBY2]
synonym: "CaM-kinase kinase 1 (mouse)" EXACT [UniProtKB:Q8VBY2]
synonym: "CaM-kinase IV kinase (mouse)" EXACT [UniProtKB:Q8VBY2]
synonym: "CaM-kinase kinase alpha (mouse)" EXACT [UniProtKB:Q8VBY2]
synonym: "calcium/calmodulin-dependent protein kinase kinase alpha (mouse)" EXACT [UniProtKB:Q8VBY2]
xref: UniProtKB:Q8VBY2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000004994 ! calcium/calmodulin-dependent protein kinase kinase 1
relationship: has_gene_template MGI:1891766 ! Camkk1 (mouse)

[Term]
id: PR:000046560
name: calcium/calmodulin-dependent protein kinase kinase 1 phosphorylated form (human)
def: "A calcium/calmodulin-dependent protein kinase kinase 1 (human) that includes at least one phosphorylated residue. UniProtKB:Q8N5S9, MOD:00696." [PRO:DNx, Reactome:R-HSA-444232]
comment: Category=organism-modification.
synonym: "hCAMKK1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8N5S9, MOD:00696" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-444232 "PR:000046560 located_in GO:0005829"
xref: Reactome:R-HSA-9619356 "PR:000046560 located_in GO:0005829"
intersection_of: has_part MOD:00696 ! phosphorylated residue
intersection_of: PR:Q8N5S9 ! calcium/calmodulin-dependent protein kinase kinase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000004994
name: calcium/calmodulin-dependent protein kinase kinase 1
def: "A protein that is a translation product of the human CAMKK1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Camkk" RELATED Gene-based []
synonym: "CAMKK1" EXACT PRO-short-label [PRO:DNx]
synonym: "CAMKKA" RELATED Gene-based []
synonym: "CaMKK 1" EXACT []
synonym: "CaM-KK 1" EXACT []
synonym: "CaMKK alpha" EXACT []
synonym: "CaM-KK alpha" EXACT []
synonym: "CaM-kinase kinase 1" EXACT []
synonym: "CaM-kinase IV kinase" EXACT []
synonym: "CaM-kinase kinase alpha" EXACT []
synonym: "calcium/calmodulin-dependent protein kinase kinase alpha" EXACT []
xref: IUPHARobj:1956
is_a: PR:000000001 ! protein

[Term]
id: PR:Q3Y416
name: calcium/calmodulin-dependent protein kinase kinase (worm)
def: "A calcium/calmodulin-dependent protein kinase kinase 1 that is encoded in the genome of worm." [OMA:Q3Y416, PANTHER:PTHR24347:SF40, PRO:DNx]
comment: Category=organism-gene.
synonym: "ckk-1" RELATED Gene-based [UniProtKB:Q3Y416]
synonym: "C05H8.1" RELATED Gene-based [UniProtKB:Q3Y416]
synonym: "CAMKK1 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "CaM-KK (worm)" EXACT [UniProtKB:Q3Y416]
synonym: "CaM-kinase kinase (worm)" EXACT [UniProtKB:Q3Y416]
xref: UniProtKB:Q3Y416
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000004994 ! calcium/calmodulin-dependent protein kinase kinase 1
relationship: has_gene_template WormBase:WBGene00000518 ! ckk-1 (worm)

[Term]
id: PR:Q8N5S9-1
name: calcium/calmodulin-dependent protein kinase kinase 1 isoform 1 (human)
def: "A calcium/calmodulin-dependent protein kinase kinase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hCAMKK1/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "calcium/calmodulin-dependent protein kinase kinase 1 isoform A (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "calcium/calmodulin-dependent protein kinase kinase 1 isoform Variant 3 (human)" EXACT [UniProtKB:Q8N5S9]
xref: UniProtKB:Q8N5S9-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000041866 ! calcium/calmodulin-dependent protein kinase kinase 1 isoform 1

[Term]
id: PR:Q8N5S9-2
name: calcium/calmodulin-dependent protein kinase kinase 1 isoform h2 (human)
def: "A calcium/calmodulin-dependent protein kinase kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N5S9-2." [PRO:DNx, UniProtKB:Q8N5S9]
comment: Category=organism-sequence.
synonym: "hCAMKK1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "calcium/calmodulin-dependent protein kinase kinase 1 isoform B (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "calcium/calmodulin-dependent protein kinase kinase 1 isoform Variant 1 (human)" EXACT [UniProtKB:Q8N5S9]
xref: UniProtKB:Q8N5S9-2
is_a: PR:Q8N5S9 ! calcium/calmodulin-dependent protein kinase kinase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q3Y416-2
name: calcium/calmodulin-dependent protein kinase kinase isoform a (worm)
def: "A calcium/calmodulin-dependent protein kinase kinase (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3Y416-2." [PRO:DNx, UniProtKB:Q3Y416]
comment: Category=organism-sequence.
synonym: "CAMKK1/iso:a (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q3Y416-2
is_a: PR:Q3Y416 ! calcium/calmodulin-dependent protein kinase kinase (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:Q3Y416-1
name: calcium/calmodulin-dependent protein kinase kinase isoform b (worm)
def: "A calcium/calmodulin-dependent protein kinase kinase (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3Y416-1." [PRO:DNx, UniProtKB:Q3Y416]
comment: Category=organism-sequence.
synonym: "CAMKK1/iso:b (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q3Y416-1
is_a: PR:Q3Y416 ! calcium/calmodulin-dependent protein kinase kinase (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:Q8VBY2-1
name: calcium/calmodulin-dependent protein kinase kinase 1 isoform 1 (mouse)
def: "A calcium/calmodulin-dependent protein kinase kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mCAMKK1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8VBY2-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000041866 ! calcium/calmodulin-dependent protein kinase kinase 1 isoform 1

[Term]
id: PR:P97756
name: calcium/calmodulin-dependent protein kinase kinase 1 (rat)
def: "A calcium/calmodulin-dependent protein kinase kinase 1 that is encoded in the genome of rat." [PANTHER:PTHR24347:SF40, PRO:DNx]
comment: Category=organism-gene.
synonym: "Camkk1" RELATED Gene-based [UniProtKB:P97756]
synonym: "rCAMKK1" EXACT PRO-short-label [PRO:DNx]
synonym: "CaMKK 1 (rat)" EXACT [UniProtKB:P97756]
synonym: "CaM-KK 1 (rat)" EXACT [UniProtKB:P97756]
synonym: "CaMKK alpha (rat)" EXACT [UniProtKB:P97756]
synonym: "CaM-KK alpha (rat)" EXACT [UniProtKB:P97756]
synonym: "CaM-kinase kinase 1 (rat)" EXACT [UniProtKB:P97756]
synonym: "CaM-kinase IV kinase (rat)" EXACT [UniProtKB:P97756]
synonym: "CaM-kinase kinase alpha (rat)" EXACT [UniProtKB:P97756]
synonym: "calcium/calmodulin-dependent protein kinase kinase alpha (rat)" EXACT [UniProtKB:P97756]
xref: UniProtKB:P97756
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000004994 ! calcium/calmodulin-dependent protein kinase kinase 1
relationship: has_gene_template RGD:62023 ! Camkk1 (rat)

[Term]
id: PR:000041866
name: calcium/calmodulin-dependent protein kinase kinase 1 isoform 1
def: "A calcium/calmodulin-dependent protein kinase kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N5S9-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "CAMKK1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000004994 ! calcium/calmodulin-dependent protein kinase kinase 1

[Term]
id: PR:Q8N5S9
name: calcium/calmodulin-dependent protein kinase kinase 1 (human)
def: "A calcium/calmodulin-dependent protein kinase kinase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8N5S9]
comment: Category=organism-gene.
synonym: "CAMKK1" RELATED Gene-based [UniProtKB:Q8N5S9]
synonym: "CAMKKA" RELATED Gene-based [UniProtKB:Q8N5S9]
synonym: "hCAMKK1" EXACT PRO-short-label [PRO:DNx]
synonym: "CaMKK 1 (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "CaM-KK 1 (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "CaMKK alpha (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "CaM-KK alpha (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "CaM-kinase kinase 1 (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "CaM-kinase IV kinase (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "CaM-kinase kinase alpha (human)" EXACT [UniProtKB:Q8N5S9]
synonym: "calcium/calmodulin-dependent protein kinase kinase alpha (human)" EXACT [UniProtKB:Q8N5S9]
xref: UniProtKB:Q8N5S9
xref: Reactome:R-HSA-442775 "PR:Q8N5S9 located_in GO:0005829"
xref: Reactome:R-HSA-9619232 "PR:Q8N5S9 located_in GO:0005829"
xref: DTO:03100232
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004994 ! calcium/calmodulin-dependent protein kinase kinase 1
relationship: has_gene_template HGNC:1469 ! CAMKK1 (human)

[Term]
id: PR:P97756-1
name: calcium/calmodulin-dependent protein kinase kinase 1 isoform 1 (rat)
def: "A calcium/calmodulin-dependent protein kinase kinase 1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rCAMKK1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P97756-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000041866 ! calcium/calmodulin-dependent protein kinase kinase 1 isoform 1