[Term]
id: PR:000004993
name: calcium/calmodulin-dependent protein kinase type IV
def: "A protein that is a translation product of the human CAMK4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CAMK" RELATED Gene-based []
synonym: "CAMK4" EXACT PRO-short-label [PRO:DNx]
synonym: "CAMKIV" RELATED Gene-based []
synonym: "CAMK-GR" RELATED Gene-based []
synonym: "CaMK IV" EXACT []
synonym: "CaM kinase-GR" EXACT []
xref: IUPHARobj:1955
is_a: PR:000000001 ! protein

[Term]
id: PR:000046559
name: calcium/calmodulin-dependent protein kinase type IV phosphorylated 2 (human)
def: "A calcium/calmodulin-dependent protein kinase type IV (human) that has been post-translationally modified to include phosphoserine at positions 12 and 13 of the amino acid sequence represented by UniProtKB:Q16566. UniProtKB:Q16566, Ser-12/Ser-13, MOD:00046." [PRO:DNx, Reactome:R-HSA-111902]
comment: Category=organism-modification.
synonym: "hCAMK4/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16566, Ser-12/Ser-13, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-111902 "PR:000046559 located_in GO:0005654"
is_a: PR:Q16566 ! calcium/calmodulin-dependent protein kinase type IV (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P13234
name: calcium/calmodulin-dependent protein kinase type IV (rat)
def: "A calcium/calmodulin-dependent protein kinase type IV that is encoded in the genome of rat." [OMA:P13234, PRO:DNx]
comment: Category=organism-gene.
synonym: "Camk4" RELATED Gene-based [UniProtKB:P13234]
synonym: "rCAMK4" EXACT PRO-short-label [PRO:DNx]
synonym: "CaMK IV (rat)" EXACT [UniProtKB:P13234]
synonym: "calspermin (rat)" EXACT [UniProtKB:P13234]
synonym: "CaM kinase-GR (rat)" EXACT [UniProtKB:P13234]
xref: UniProtKB:P13234
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000004993 ! calcium/calmodulin-dependent protein kinase type IV
relationship: has_gene_template RGD:2264 ! Camk4 (rat)

[Term]
id: PR:000045956
name: calcium/calmodulin-dependent protein kinase type IV phosphorylated 1 (human)
def: "A calcium/calmodulin-dependent protein kinase type IV (human) that has been phosphorylated at Thr-200. UniProtKB:Q16566, Thr-200, MOD:00047." [PMID:15143065, PMID:19506079, iPTMnet:Q16566]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:15143065, PMID:19506079). Status=unreviewed.
synonym: "hCAMK4/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16566, Thr-200, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-9619155 "PR:000045956 located_in GO:0005654"
is_a: PR:Q16566 ! calcium/calmodulin-dependent protein kinase type IV (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16566
name: calcium/calmodulin-dependent protein kinase type IV (human)
def: "A calcium/calmodulin-dependent protein kinase type IV that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q16566]
comment: Category=organism-gene.
synonym: "CAMK" RELATED Gene-based [UniProtKB:Q16566]
synonym: "CAMK4" RELATED Gene-based [UniProtKB:Q16566]
synonym: "CAMKIV" RELATED Gene-based [UniProtKB:Q16566]
synonym: "hCAMK4" EXACT PRO-short-label [PRO:DNx]
synonym: "CAMK-GR" RELATED Gene-based [UniProtKB:Q16566]
synonym: "CaMK IV (human)" EXACT [UniProtKB:Q16566]
synonym: "CaM kinase-GR (human)" EXACT [UniProtKB:Q16566]
xref: Reactome:R-HSA-57900 "PR:Q16566 located_in GO:0005829"
xref: DTO:03100222
xref: UniProtKB:Q16566
xref: Reactome:R-HSA-112280 "PR:Q16566 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004993 ! calcium/calmodulin-dependent protein kinase type IV
relationship: has_gene_template HGNC:1464 ! CAMK4 (human)

[Term]
id: PR:P13234-2
name: calcium/calmodulin-dependent protein kinase type IV isoform r2 (rat)
def: "A calcium/calmodulin-dependent protein kinase type IV (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13234-2." [PRO:DNx, UniProtKB:P13234]
comment: Category=organism-sequence.
synonym: "rCAMK4/iso:r2" EXACT PRO-short-label [PRO:DNx]
synonym: "calcium/calmodulin-dependent protein kinase type IV isoform Calspermin (rat)" EXACT [UniProtKB:P13234]
synonym: "calcium/calmodulin-dependent protein kinase type IV isoform Testis-specific (rat)" EXACT [UniProtKB:P13234]
xref: UniProtKB:P13234-2
is_a: PR:P13234 ! calcium/calmodulin-dependent protein kinase type IV (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P13234-1
name: calcium/calmodulin-dependent protein kinase type IV isoform r1 (rat)
def: "A calcium/calmodulin-dependent protein kinase type IV (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13234-1." [PRO:DNx, UniProtKB:P13234]
comment: Category=organism-sequence.
synonym: "rCAMK4/iso:r1" EXACT PRO-short-label [PRO:DNx]
synonym: "calcium/calmodulin-dependent protein kinase type IV isoform Beta (rat)" EXACT [UniProtKB:P13234]
synonym: "calcium/calmodulin-dependent protein kinase type IV isoform Calcium-calmodulin-dependent protein kinase type IV (rat)" EXACT [UniProtKB:P13234]
xref: UniProtKB:P13234-1
is_a: PR:P13234 ! calcium/calmodulin-dependent protein kinase type IV (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000046140
name: calcium/calmodulin-dependent protein kinase type IV phosphorylated 1 (rat)
def: "A calcium/calmodulin-dependent protein kinase type IV (rat) that has been phosphorylated at the position equivalent to Ser-437 of the amino acid sequence represented by UniProtKB:P13234-1. Example: UniProtKB:P13234-1, Ser-437, MOD:00046." [PMID:8340352, iPTMnet:P13234]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:8340352). Status=unreviewed.
synonym: "rCAMK4/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P13234-1, Ser-437, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P13234 ! calcium/calmodulin-dependent protein kinase type IV (rat)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P08414
name: calcium/calmodulin-dependent protein kinase type IV (mouse)
def: "A calcium/calmodulin-dependent protein kinase type IV that is encoded in the genome of mouse." [OMA:P08414, PRO:DNx]
comment: Category=organism-gene.
synonym: "Camk4" RELATED Gene-based [UniProtKB:P08414]
synonym: "mCAMK4" EXACT PRO-short-label [PRO:DNx]
synonym: "CaMK IV (mouse)" EXACT [UniProtKB:P08414]
synonym: "CaM kinase-GR (mouse)" EXACT [UniProtKB:P08414]
xref: UniProtKB:P08414
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000004993 ! calcium/calmodulin-dependent protein kinase type IV
relationship: has_gene_template MGI:88258 ! Camk4 (mouse)