[Term]
id: PR:000046414
name: serine-protein kinase ATM acetylated 1 (human)
def: "A serine-protein kinase ATM (human) that has been post-translationally modified to include N6-acetyllysine at position 3016 of the amino acid sequence represented by UniProtKB:Q13315. UniProtKB:Q13315, Lys-3016, MOD:00064." [PRO:DNx, Reactome:R-HSA-5682043]
comment: Category=organism-modification.
synonym: "hATM/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13315, Lys-3016, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5682043 "PR:000046414 located_in GO:0005654"
is_a: PR:Q13315 ! serine-protein kinase ATM (human)
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000035452
name: serine-protein kinase ATM unphosphorylated form (human)
def: "A serine-protein kinase ATM unphosphorylated form in human." [PRO:KER]
comment: Category=organism-modification.
synonym: "hATM/PhosRes-" EXACT PRO-short-label [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035451 ! serine-protein kinase ATM unphosphorylated form

[Term]
id: PR:Q13315
name: serine-protein kinase ATM (human)
def: "A serine-protein kinase ATM that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "ATM" RELATED Gene-based [UniProtKB:Q13315]
synonym: "hATM" EXACT PRO-short-label [PRO:DNx]
synonym: "A-T mutated (human)" EXACT [UniProtKB:Q13315]
synonym: "ataxia telangiectasia mutated (human)" EXACT [UniProtKB:Q13315]
xref: Reactome:R-HSA-69484 "PR:Q13315 located_in GO:0005654"
xref: Reactome:R-HSA-9665169 "PR:Q13315 located_in GO:0005782"
xref: Reactome:R-HSA-9665171 "PR:Q13315 located_in GO:0005829"
xref: DTO:03100033
xref: UniProtKB:Q13315
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004427 ! serine-protein kinase ATM
relationship: has_gene_template HGNC:795 ! ATM (human)

[Term]
id: PR:000004427
name: serine-protein kinase ATM
def: "A protein that is a translation product of the human ATM gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ATM" EXACT PRO-short-label [PRO:DNx]
synonym: "A-T mutated" EXACT []
synonym: "A-T mutated homolog" EXACT []
synonym: "ataxia telangiectasia mutated" EXACT []
synonym: "ataxia telangiectasia mutated homolog" EXACT []
xref: IUPHARobj:1934
is_a: PR:000000001 ! protein

[Term]
id: PR:Q13315-1
name: serine-protein kinase ATM isoform 1 (human)
def: "A serine-protein kinase ATM isoform 1 that is encoded in the genome of human." [PRO:CNx]
comment: Category=organism-sequence.
synonym: "hATM/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13315-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026201 ! serine-protein kinase ATM isoform 1

[Term]
id: PR:000045909
name: serine-protein kinase ATM phosphorylated 1 (human)
def: "A serine-protein kinase ATM (human) that has been phosphorylated at Tyr-370. UniProtKB:Q13315, Tyr-370, MOD:00048." [PMID:25601159, iPTMnet:Q13315]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:25601159). Status=unreviewed.
synonym: "hATM/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13315, Tyr-370, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q13315 ! serine-protein kinase ATM (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000035423
name: serine-protein kinase ATM phosphorylated 2 (human)
def: "A serine-protein kinase ATM phosphorylated 2 in human. This phosphorylated form is observed during mitosis and spindle depolymerization (nocodazole). Ser-1403 is phosphorylated by Aurora B kinase. UniProtKB:Q13315, Ser-1403/Ser-1981, MOD:00046." [PMID:22099307, PRO:KER]
comment: Category=organism-modification. Kinase=("AURKB"; PR:Q96GD4).
synonym: "hATM/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13315, Ser-1403/Ser-1981, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035422 ! serine-protein kinase ATM phosphorylated 2
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000026217
name: serine-protein kinase ATM isoform 1 phosphorylated 1 (human)
def: "A serine-protein kinase ATM isoform 1 phosphorylated 1 in human. UniProtKB:Q13315-1, Ser-1981, MOD:00046." [PRO:CNx]
comment: Category=organism-modification.
synonym: "hATM/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13315-1, Ser-1981, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026203 ! serine-protein kinase ATM isoform 1 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine