[Term]
id: PR:P55088-2
name: aquaporin-4 isoform 1 (mouse)
def: "An aquaporin-4 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mAQP4/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "aquaporin-4 isoform MIWC1 (mouse)" EXACT [UniProtKB:P55088]
synonym: "aquaporin-4 isoform AQP4-M21 (mouse)" EXACT [UniProtKB:P55088]
xref: UniProtKB:P55088-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039790 ! aquaporin-4 isoform 2

[Term]
id: PR:000004184
name: aquaporin-4
def: "An aquaporin protein that is a translation product of the human AQP4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "AQP4" EXACT PRO-short-label [PRO:DNx]
synonym: "MIWC" EXACT []
synonym: "WCH4" EXACT []
synonym: "AQP-4" EXACT []
synonym: "mercurial-insensitive water channel" EXACT []
xref: IUPHARobj:691
is_a: PR:000044672 ! aquaporin protein

[Term]
id: PR:P55088
name: aquaporin-4 (mouse)
def: "An aquaporin-4 that is encoded in the genome of mouse." [OMA:P55088, PRO:DNx]
comment: Category=organism-gene.
synonym: "Aqp4" RELATED Gene-based [UniProtKB:P55088]
synonym: "mAQP4" EXACT PRO-short-label [PRO:DNx]
synonym: "MIWC (mouse)" EXACT [UniProtKB:P55088]
synonym: "WCH4 (mouse)" EXACT [UniProtKB:P55088]
synonym: "AQP-4 (mouse)" EXACT [UniProtKB:P55088]
synonym: "mercurial-insensitive water channel (mouse)" EXACT [UniProtKB:P55088]
xref: UniProtKB:P55088
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000004184 ! aquaporin-4
relationship: has_gene_template MGI:107387 ! Aqp4 (mouse)

[Term]
id: PR:P47863-2
name: aquaporin-4 isoform Short (rat)
def: "An aquaporin-4 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P47863-2." [PRO:DNx, UniProtKB:P47863]
comment: Category=organism-sequence.
synonym: "rAQP4/iso:Short" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P47863-2
is_a: PR:P47863 ! aquaporin-4 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000045838
name: aquaporin-4 phosphorylated 1 (human)
def: "An aquaporin-4 (human) that has been phosphorylated at the position equivalent to Ser-276 of the amino acid sequence represented by UniProtKB:P55087-1. Example: UniProtKB:P55087-1, Ser-276, MOD:00046." [PMID:26013827, iPTMnet:P55087]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:26013827). Status=unreviewed.
synonym: "hAQP4/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P55087-1, Ser-276, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P55087 ! aquaporin-4 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P55088-3
name: aquaporin-4 isoform m3 (mouse)
def: "An aquaporin-4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55088-3." [PRO:DNx, UniProtKB:P55088]
comment: Category=organism-sequence.
synonym: "mAQP4/iso:m3" EXACT PRO-short-label [PRO:DNx]
synonym: "aquaporin-4 isoform MIWC3 (mouse)" EXACT [UniProtKB:P55088]
xref: UniProtKB:P55088-3
is_a: PR:P55088 ! aquaporin-4 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P55087-1
name: aquaporin-4 isoform 2 (human)
def: "An aquaporin-4 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hAQP4/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P55087-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039789 ! aquaporin-4 isoform 1

[Term]
id: PR:P55087
name: aquaporin-4 (human)
def: "An aquaporin-4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P55087]
comment: Category=organism-gene.
synonym: "AQP4" RELATED Gene-based [UniProtKB:P55087]
synonym: "hAQP4" EXACT PRO-short-label [PRO:DNx]
synonym: "MIWC (human)" EXACT [UniProtKB:P55087]
synonym: "WCH4 (human)" EXACT [UniProtKB:P55087]
synonym: "AQP-4 (human)" EXACT [UniProtKB:P55087]
synonym: "mercurial-insensitive water channel (human)" EXACT [UniProtKB:P55087]
xref: Reactome:R-HSA-431733 "PR:P55087 located_in GO:0005886"
xref: UniProtKB:P55087
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004184 ! aquaporin-4
relationship: has_gene_template HGNC:637 ! AQP4 (human)

[Term]
id: PR:P47863
name: aquaporin-4 (rat)
def: "An aquaporin-4 that is encoded in the genome of rat." [OMA:P47863, PANTHER:PTHR19139:SF34, PRO:DNx]
comment: Category=organism-gene.
synonym: "Aqp4" RELATED Gene-based [UniProtKB:P47863]
synonym: "rAQP4" EXACT PRO-short-label [PRO:DNx]
synonym: "MIWC (rat)" EXACT [UniProtKB:P47863]
synonym: "WCH4 (rat)" EXACT [UniProtKB:P47863]
synonym: "AQP-4 (rat)" EXACT [UniProtKB:P47863]
synonym: "mercurial-insensitive water channel (rat)" EXACT [UniProtKB:P47863]
xref: UniProtKB:P47863
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000004184 ! aquaporin-4
relationship: has_gene_template RGD:2143 ! Aqp4 (rat)

[Term]
id: PR:P55088-1
name: aquaporin-4 isoform 2 (mouse)
def: "An aquaporin-4 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mAQP4/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "aquaporin-4 isoform MIWC2 (mouse)" EXACT [UniProtKB:P55088]
synonym: "aquaporin-4 isoform AQP4-M1 (mouse)" EXACT [UniProtKB:P55088]
xref: UniProtKB:P55088-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039789 ! aquaporin-4 isoform 1

[Term]
id: PR:P47863-1
name: aquaporin-4 isoform Long (rat)
def: "An aquaporin-4 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rAQP4/iso:Long" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P47863-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000039789 ! aquaporin-4 isoform 1

[Term]
id: PR:000039789
name: aquaporin-4 isoform 1
def: "An aquaporin-4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55087-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "AQP4/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000004184 ! aquaporin-4

[Term]
id: PR:P47863-3
name: aquaporin-4 isoform r3 (rat)
def: "An aquaporin-4 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P47863-3." [PRO:DNx, UniProtKB:P47863]
comment: Category=organism-sequence.
synonym: "rAQP4/iso:r3" EXACT PRO-short-label [PRO:DNx]
synonym: "aquaporin-4 isoform AQP4-M23 (rat)" EXACT [UniProtKB:P47863]
xref: UniProtKB:P47863-3
is_a: PR:P47863 ! aquaporin-4 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000039790
name: aquaporin-4 isoform 2
def: "An aquaporin-4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55087-2 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "AQP4/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000004184 ! aquaporin-4

[Term]
id: PR:P55087-2
name: aquaporin-4 isoform 1 (human)
def: "An aquaporin-4 isoform 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hAQP4/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P55087-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039790 ! aquaporin-4 isoform 2