[Term] id: PR:Q02252-2 name: methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform h2 (human) def: "A methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02252-2." [PRO:DNx, UniProtKB:Q02252] comment: Category=organism-sequence. synonym: "hALDH6A1/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q02252-2 is_a: PR:Q02252 ! methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000003930 name: methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial def: "A protein that is a translation product of the human ALDH6A1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "MMSDH" RELATED Gene-based [] synonym: "ALDH6A1" EXACT PRO-short-label [PRO:DNx] synonym: "aldehyde dehydrogenase family 6 member A1" EXACT [] synonym: "malonate-semialdehyde dehydrogenase [acylating]" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q02253 name: methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (rat) def: "A methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial that is encoded in the genome of rat." [PANTHER:PTHR11699:SF27, PRO:DNx] comment: Category=organism-gene. synonym: "Mmsdh" RELATED Gene-based [UniProtKB:Q02253] synonym: "Aldh6a1" RELATED Gene-based [UniProtKB:Q02253] synonym: "rALDH6A1" EXACT PRO-short-label [PRO:DNx] synonym: "MMSDH (rat)" EXACT [UniProtKB:Q02253] synonym: "aldehyde dehydrogenase family 6 member A1 (rat)" EXACT [UniProtKB:Q02253] synonym: "malonate-semialdehyde dehydrogenase [acylating] (rat)" EXACT [UniProtKB:Q02253] xref: UniProtKB:Q02253 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000003930 ! methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial relationship: has_gene_template RGD:621556 ! Aldh6a1 (rat) [Term] id: PR:Q02252-1 name: methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform h1 (human) def: "A methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02252-1." [PRO:DNx, UniProtKB:Q02252] comment: Category=organism-sequence. synonym: "hALDH6A1/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q02252-1 is_a: PR:Q02252 ! methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q0WM29-1 name: methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform 1 (Arabidopsis thaliana) def: "A methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q0WM29-1." [PRO:DNx, UniProtKB:Q0WM29] comment: Category=organism-sequence. synonym: "At-ALDH6A1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q0WM29-1 is_a: PR:Q0WM29 ! methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (Arabidopsis thaliana) relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana [Term] id: PR:Q0WM29 name: methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (Arabidopsis thaliana) def: "A methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial that is encoded in the genome of Arabidopsis thaliana." [OMA:Q0WM29, PRO:DNx] comment: Category=organism-gene. synonym: "ALDH6B2" RELATED Gene-based [UniProtKB:Q0WM29] synonym: "F15N24.6" RELATED Gene-based [UniProtKB:Q0WM29] synonym: "At2g14170" RELATED Gene-based [UniProtKB:Q0WM29] synonym: "T22C12.10" RELATED Gene-based [UniProtKB:Q0WM29] synonym: "At-ALDH6A1" EXACT PRO-short-label [PRO:DNx] synonym: "MMSDH (Arabidopsis thaliana)" EXACT [UniProtKB:Q0WM29] synonym: "MM-ALDH (Arabidopsis thaliana)" EXACT [UniProtKB:Q0WM29] synonym: "aldehyde dehydrogenase family 6 member B2 (Arabidopsis thaliana)" EXACT [UniProtKB:Q0WM29] synonym: "malonate-semialdehyde dehydrogenase [acylating] (Arabidopsis thaliana)" EXACT [UniProtKB:Q0WM29] xref: UniProtKB:Q0WM29 intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana intersection_of: PR:000003930 ! methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial relationship: has_gene_template Araport:AT2G14170 ! ALDH6B2 (Arabidopsis thaliana) [Term] id: PR:Q9EQ20 name: methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (mouse) def: "A methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial that is encoded in the genome of mouse." [OMA:Q9EQ20, PRO:DNx] comment: Category=organism-gene. synonym: "Aldh6a1" RELATED Gene-based [UniProtKB:Q9EQ20] synonym: "mALDH6A1" EXACT PRO-short-label [PRO:DNx] synonym: "MMSDH (mouse)" EXACT [UniProtKB:Q9EQ20] synonym: "aldehyde dehydrogenase family 6 member A1 (mouse)" EXACT [UniProtKB:Q9EQ20] synonym: "malonate-semialdehyde dehydrogenase [acylating] (mouse)" EXACT [UniProtKB:Q9EQ20] xref: UniProtKB:Q9EQ20 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000003930 ! methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial relationship: has_gene_template MGI:1915077 ! Aldh6a1 (mouse) [Term] id: PR:Q7KW39 name: probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (fruit fly) def: "A methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial that is encoded in the genome of fruit fly." [OMA:Q7KW39, PRO:DNx] comment: Category=organism-gene. synonym: "CG17896" RELATED Gene-based [UniProtKB:Q7KW39] synonym: "fly-ALDH6A1" EXACT PRO-short-label [PRO:DNx] synonym: "MMSDH (fruit fly)" EXACT [UniProtKB:Q7KW39] synonym: "malonate-semialdehyde dehydrogenase [acylating] (fruit fly)" EXACT [UniProtKB:Q7KW39] xref: UniProtKB:Q7KW39 intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster intersection_of: PR:000003930 ! methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial relationship: has_gene_template FlyBase:FBgn0023537 ! CG17896 (fruit fly) [Term] id: PR:Q54I10 name: probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (Dictyostelium discoideum) def: "A methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54I10, PRO:DNx] comment: Category=organism-gene. synonym: "aldh6" RELATED Gene-based [UniProtKB:Q54I10] synonym: "mmsdh" RELATED Gene-based [UniProtKB:Q54I10] synonym: "DDB_G0289085" RELATED Gene-based [UniProtKB:Q54I10] synonym: "Dicty-ALDH6A1" EXACT PRO-short-label [PRO:DNx] synonym: "MMSDH (Dictyostelium discoideum)" EXACT [UniProtKB:Q54I10] synonym: "malonate-semialdehyde dehydrogenase [acylating] (Dictyostelium discoideum)" EXACT [UniProtKB:Q54I10] xref: UniProtKB:Q54I10 intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum intersection_of: PR:000003930 ! methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial relationship: has_gene_template dictyBase:DDB_G0289085 ! mmsdh (Dictyostelium discoideum) [Term] id: PR:000043149 name: methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform 1 def: "A methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9EQ20-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "ALDH6A1/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000003930 ! methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial [Term] id: PR:Q02252 name: methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (human) def: "A methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q02252] comment: Category=organism-gene. synonym: "MMSDH" RELATED Gene-based [UniProtKB:Q02252] synonym: "ALDH6A1" RELATED Gene-based [UniProtKB:Q02252] synonym: "hALDH6A1" EXACT PRO-short-label [PRO:DNx] synonym: "aldehyde dehydrogenase family 6 member A1 (human)" EXACT [UniProtKB:Q02252] synonym: "malonate-semialdehyde dehydrogenase [acylating] (human)" EXACT [UniProtKB:Q02252] xref: UniProtKB:Q02252 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000003930 ! methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial relationship: has_gene_template HGNC:7179 ! ALDH6A1 (human) [Term] id: PR:P52713 name: probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (worm) def: "A methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial that is encoded in the genome of worm." [OMA:P52713, PRO:DNx] comment: Category=organism-gene. synonym: "alh-8" RELATED Gene-based [UniProtKB:P52713] synonym: "F13D12.4" RELATED Gene-based [UniProtKB:P52713] synonym: "MMSDH (worm)" EXACT [UniProtKB:P52713] synonym: "ALDH6A1 (worm)" EXACT PRO-short-label [PRO:DNx] synonym: "malonate-semialdehyde dehydrogenase [acylating] (worm)" EXACT [UniProtKB:P52713] xref: UniProtKB:P52713 intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans intersection_of: PR:000003930 ! methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial relationship: has_gene_template WormBase:WBGene00000114 ! alh-8 (worm) [Term] id: PR:Q7KW39-2 name: probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform A (fruit fly) def: "A probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7KW39-2." [PRO:DNx, UniProtKB:Q7KW39] comment: Category=organism-sequence. synonym: "fly-ALDH6A1/iso:A" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q7KW39-2 is_a: PR:Q7KW39 ! probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:Q9EQ20-1 name: methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform 1 (mouse) def: "A methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mALDH6A1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9EQ20-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000043149 ! methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform 1 [Term] id: PR:Q7KW39-1 name: probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform B (fruit fly) def: "A probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7KW39-1." [PRO:DNx, UniProtKB:Q7KW39] comment: Category=organism-sequence. synonym: "fly-ALDH6A1/iso:B" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q7KW39-1 is_a: PR:Q7KW39 ! probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:Q02253-1 name: methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform 1 (rat) def: "A methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rALDH6A1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q02253-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000043149 ! methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform 1 [Term] id: PR:000046315 name: methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial, transit peptide removed form (human) def: "A methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (human) that has had the transit peptide removed. UniProtKB:Q02252, 34-535." [PRO:DNx, Reactome:R-HSA-70890] comment: Category=organism-modification. synonym: "PRO_0000007189" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hALDH6A1/TransPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q02252, 34-535" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-70890 "PR:000046315 located_in GO:0005759" intersection_of: PR:Q02252 ! methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (human) intersection_of: lacks_part SO:0000725 ! transit_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens