[Term] id: PR:000003919 name: delta-1-pyrroline-5-carboxylate synthase def: "A protein that is a translation product of the human ALDH18A1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "GSAS" RELATED Gene-based [] synonym: "P5CS" RELATED Gene-based [] synonym: "PYCS" RELATED Gene-based [] synonym: "ALDH18A1" EXACT PRO-short-label [PRO:DNx] synonym: "aldehyde dehydrogenase family 18 member A1" EXACT [] synonym: "delta-1-pyrroline-5-carboxylate synthetase" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:P54886-2 name: delta-1-pyrroline-5-carboxylate synthase isoform Short (human) def: "A delta-1-pyrroline-5-carboxylate synthase isoform 2 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hALDH18A1/iso:Short" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P54886-2 xref: Reactome:R-HSA-508031 "PR:P54886-2 located_in GO:0005743" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000039777 ! delta-1-pyrroline-5-carboxylate synthase isoform 2 [Term] id: PR:P54886-1 name: delta-1-pyrroline-5-carboxylate synthase isoform Long (human) def: "A delta-1-pyrroline-5-carboxylate synthase isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hALDH18A1/iso:Long" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P54886-1 xref: Reactome:R-HSA-508039 "PR:P54886-1 located_in GO:0005743" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000039776 ! delta-1-pyrroline-5-carboxylate synthase isoform 1 [Term] id: PR:P54889-1 name: probable delta-1-pyrroline-5-carboxylate synthase isoform b (worm) def: "A probable delta-1-pyrroline-5-carboxylate synthase (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P54889-1." [PRO:DNx, UniProtKB:P54889] comment: Category=organism-sequence. synonym: "ALDH18A1/iso:b (worm)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P54889-1 is_a: PR:P54889 ! probable delta-1-pyrroline-5-carboxylate synthase (worm) relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans [Term] id: PR:000039776 name: delta-1-pyrroline-5-carboxylate synthase isoform 1 def: "A delta-1-pyrroline-5-carboxylate synthase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P54886-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "ALDH18A1/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000003919 ! delta-1-pyrroline-5-carboxylate synthase [Term] id: PR:000039777 name: delta-1-pyrroline-5-carboxylate synthase isoform 2 def: "A delta-1-pyrroline-5-carboxylate synthase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P54886-2 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "ALDH18A1/iso:2" EXACT PRO-short-label [PRO:DNx] is_a: PR:000003919 ! delta-1-pyrroline-5-carboxylate synthase [Term] id: PR:P54889-2 name: probable delta-1-pyrroline-5-carboxylate synthase isoform a (worm) def: "A probable delta-1-pyrroline-5-carboxylate synthase (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P54889-2." [PRO:DNx, UniProtKB:P54889] comment: Category=organism-sequence. synonym: "ALDH18A1/iso:a (worm)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P54889-2 is_a: PR:P54889 ! probable delta-1-pyrroline-5-carboxylate synthase (worm) relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans [Term] id: PR:P54889 name: probable delta-1-pyrroline-5-carboxylate synthase (worm) def: "A delta-1-pyrroline-5-carboxylate synthase that is encoded in the genome of worm." [OMA:P54889, PANTHER:PTHR11063:SF2, PRO:DNx] comment: Category=organism-gene. synonym: "alh-13" RELATED Gene-based [UniProtKB:P54889] synonym: "T22H6.2" RELATED Gene-based [UniProtKB:P54889] synonym: "P5CS (worm)" EXACT [UniProtKB:P54889] synonym: "ALDH18A1 (worm)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P54889 intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans intersection_of: PR:000003919 ! delta-1-pyrroline-5-carboxylate synthase relationship: has_gene_template WormBase:WBGene00011938 ! alh-13 (worm) [Term] id: PR:Q9Z110 name: delta-1-pyrroline-5-carboxylate synthase (mouse) def: "A delta-1-pyrroline-5-carboxylate synthase that is encoded in the genome of mouse." [OMA:Q9Z110, PRO:DNx] comment: Category=organism-gene. synonym: "P5cs" RELATED Gene-based [UniProtKB:Q9Z110] synonym: "Pycs" RELATED Gene-based [UniProtKB:Q9Z110] synonym: "Aldh18a1" RELATED Gene-based [UniProtKB:Q9Z110] synonym: "mALDH18A1" EXACT PRO-short-label [PRO:DNx] synonym: "P5CS (mouse)" EXACT [UniProtKB:Q9Z110] synonym: "aldehyde dehydrogenase family 18 member A1 (mouse)" EXACT [UniProtKB:Q9Z110] xref: UniProtKB:Q9Z110 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000003919 ! delta-1-pyrroline-5-carboxylate synthase relationship: has_gene_template MGI:1888908 ! Aldh18a1 (mouse) [Term] id: PR:P54886 name: delta-1-pyrroline-5-carboxylate synthase (human) def: "A delta-1-pyrroline-5-carboxylate synthase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P54886] comment: Category=organism-gene. synonym: "GSAS" RELATED Gene-based [UniProtKB:P54886] synonym: "P5CS" RELATED Gene-based [UniProtKB:P54886] synonym: "PYCS" RELATED Gene-based [UniProtKB:P54886] synonym: "ALDH18A1" RELATED Gene-based [UniProtKB:P54886] synonym: "hALDH18A1" EXACT PRO-short-label [PRO:DNx] synonym: "aldehyde dehydrogenase family 18 member A1 (human)" EXACT [UniProtKB:P54886] xref: UniProtKB:P54886 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000003919 ! delta-1-pyrroline-5-carboxylate synthase relationship: has_gene_template HGNC:9722 ! ALDH18A1 (human) [Term] id: PR:Q9Z110-2 name: delta-1-pyrroline-5-carboxylate synthase isoform Short (mouse) def: "A delta-1-pyrroline-5-carboxylate synthase isoform 2 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mALDH18A1/iso:Short" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9Z110-2 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000039777 ! delta-1-pyrroline-5-carboxylate synthase isoform 2 [Term] id: PR:Q9Z110-1 name: delta-1-pyrroline-5-carboxylate synthase isoform Long (mouse) def: "A delta-1-pyrroline-5-carboxylate synthase isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mALDH18A1/iso:Long" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9Z110-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000039776 ! delta-1-pyrroline-5-carboxylate synthase isoform 1