[Term]
id: PR:Q9YHT4
name: 5-aminolevulinate synthase, erythroid-specific, mitochondrial (zebrafish)
def: "A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is encoded in the genome of zebrafish." [OMA:Q9YHT4, PANTHER:PTHR13693:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "alas2" RELATED Gene-based [UniProtKB:Q9YHT4]
synonym: "alas-e" RELATED Gene-based [UniProtKB:Q9YHT4]
synonym: "z-ALAS2" EXACT PRO-short-label [PRO:DNx]
synonym: "ALAS-E (zebrafish)" EXACT [UniProtKB:Q9YHT4]
synonym: "delta-ALA synthase 2 (zebrafish)" EXACT [UniProtKB:Q9YHT4]
synonym: "5-aminolevulinic acid synthase 2 (zebrafish)" EXACT [UniProtKB:Q9YHT4]
synonym: "delta-aminolevulinate synthase 2 (zebrafish)" EXACT [UniProtKB:Q9YHT4]
xref: UniProtKB:Q9YHT4
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000003917 ! 5-aminolevulinate synthase, erythroid-specific, mitochondrial
relationship: has_gene_template ZFIN:ZDB-GENE-001229-1 ! alas2 (zebrafish)

[Term]
id: PR:Q54UX3
name: 5-aminolevulinate synthase (Dictyostelium discoideum)
def: "A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is encoded in the genome of Dictyostelium discoideum." [PANTHER:PTHR13693:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "DDB0231416" RELATED Gene-based [UniProtKB:Q54UX3]
synonym: "Dicty-ALAS2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q54UX3
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000003917 ! 5-aminolevulinate synthase, erythroid-specific, mitochondrial
relationship: has_gene_template dictyBase:DDB_G0280763 ! hemA (Dictyostelium discoideum)

[Term]
id: PR:Q63147
name: 5-aminolevulinate synthase, erythroid-specific, mitochondrial (rat)
def: "A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is encoded in the genome of rat." [OMA:Q63147, PRO:DNx]
comment: Category=organism-gene.
synonym: "Alas2" RELATED Gene-based [UniProtKB:Q63147]
synonym: "Alase" RELATED Gene-based [UniProtKB:Q63147]
synonym: "rALAS2" EXACT PRO-short-label [PRO:DNx]
synonym: "ALAS-E (rat)" EXACT [UniProtKB:Q63147]
synonym: "delta-ALA synthase 2 (rat)" EXACT [UniProtKB:Q63147]
synonym: "5-aminolevulinic acid synthase 2 (rat)" EXACT [UniProtKB:Q63147]
synonym: "delta-aminolevulinate synthase 2 (rat)" EXACT [UniProtKB:Q63147]
xref: UniProtKB:Q63147
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000003917 ! 5-aminolevulinate synthase, erythroid-specific, mitochondrial
relationship: has_gene_template RGD:2084 ! Alas2 (rat)

[Term]
id: PR:P22557
name: 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human)
def: "A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is encoded in the genome of human." [PRO:CNA, UniProtKB:P22557]
comment: Category=organism-gene.
synonym: "ASB" RELATED Gene-based [UniProtKB:P22557]
synonym: "ALAS2" RELATED Gene-based [UniProtKB:P22557]
synonym: "ALASE" RELATED Gene-based [UniProtKB:P22557]
synonym: "hALAS2" EXACT PRO-short-label [PRO:DNx]
synonym: "ALAS-E (human)" EXACT [UniProtKB:P22557]
synonym: "delta-ALA synthase 2 (human)" EXACT [UniProtKB:P22557]
synonym: "5-aminolevulinic acid synthase 2 (human)" EXACT [UniProtKB:P22557]
synonym: "delta-aminolevulinate synthase 2 (human)" EXACT [UniProtKB:P22557]
xref: UniProtKB:P22557
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003917 ! 5-aminolevulinate synthase, erythroid-specific, mitochondrial
relationship: has_gene_template HGNC:397 ! ALAS2 (human)

[Term]
id: PR:O14092
name: 5-aminolevulinate synthase, mitochondrial (Schizosaccharomyces pombe 972h-)
def: "A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O14092, PANTHER:PTHR13693:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "hem1" RELATED Gene-based [UniProtKB:O14092]
synonym: "SPAC2F3.09" RELATED Gene-based [UniProtKB:O14092]
synonym: "Spom972h-ALAS2" EXACT PRO-short-label [PRO:DNx]
synonym: "delta-ALA synthase (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O14092]
synonym: "5-aminolevulinic acid synthase (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O14092]
synonym: "delta-aminolevulinate synthase (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O14092]
xref: UniProtKB:O14092
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000003917 ! 5-aminolevulinate synthase, erythroid-specific, mitochondrial
relationship: has_gene_template PomBase:SPAC2F3.09 ! hem1 (Schizosaccharomyces pombe)

[Term]
id: PR:000003917
name: 5-aminolevulinate synthase, erythroid-specific, mitochondrial
def: "A 5-aminolevulinate synthase that is a translation product of the human ALAS2 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "ASB" RELATED Gene-based []
synonym: "ALAS2" EXACT PRO-short-label [PRO:DNx]
synonym: "ALASE" RELATED Gene-based []
synonym: "ALAS-E" EXACT []
synonym: "delta-ALA synthase 2" EXACT []
synonym: "5-aminolevulinic acid synthase 2" EXACT []
synonym: "delta-aminolevulinate synthase 2" EXACT []
is_a: PR:000026125 ! 5-aminolevulinate synthase

[Term]
id: PR:000046306
name: 5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine form (human)
def: "A 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human) that has had the transit peptide removed and that includes at least one pyridoxal phosphate lysine. UniProtKB:P22557, 50-587, MOD:00128." [PRO:DNx, Reactome:R-HSA-1022083]
comment: Category=organism-modification.
synonym: "PRO_0000001223, MOD:00128" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hALAS2/TransPep-/PyrdoxLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P22557, 50-587, MOD:00128" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1022083 "PR:000046306 located_in GO:0005759"
intersection_of: has_part MOD:00128 ! N6-pyridoxal phosphate-L-lysine
intersection_of: PR:P22557 ! 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human)
intersection_of: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P22557-1
name: 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (human)
def: "A 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hALAS2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P22557-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039074 ! 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1

[Term]
id: PR:P22557-3
name: 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform h3 (human)
def: "A 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22557-3." [PRO:DNx, UniProtKB:P22557]
comment: Category=organism-sequence.
synonym: "hALAS2/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform F143M (human)" EXACT [UniProtKB:P22557]
xref: UniProtKB:P22557-3
is_a: PR:P22557 ! 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P08680
name: 5-aminolevulinate synthase, erythroid-specific, mitochondrial (mouse)
def: "A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is encoded in the genome of mouse." [OMA:P08680, PRO:DNx]
comment: Category=organism-gene.
synonym: "Alas2" RELATED Gene-based [UniProtKB:P08680]
synonym: "mALAS2" EXACT PRO-short-label [PRO:DNx]
synonym: "ALAS-E (mouse)" EXACT [UniProtKB:P08680]
synonym: "delta-ALA synthase 2 (mouse)" EXACT [UniProtKB:P08680]
synonym: "5-aminolevulinic acid synthase 2 (mouse)" EXACT [UniProtKB:P08680]
synonym: "delta-aminolevulinate synthase 2 (mouse)" EXACT [UniProtKB:P08680]
xref: UniProtKB:P08680
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003917 ! 5-aminolevulinate synthase, erythroid-specific, mitochondrial
relationship: has_gene_template MGI:87990 ! Alas2 (mouse)

[Term]
id: PR:P09950
name: 5-aminolevulinate synthase, mitochondrial (yeast)
def: "A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is encoded in the genome of yeast." [OMA:P09950, PANTHER:PTHR13693:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "CYD1" RELATED Gene-based [UniProtKB:P09950]
synonym: "HEM1" RELATED Gene-based [UniProtKB:P09950]
synonym: "yALAS2" EXACT PRO-short-label [PRO:DNx]
synonym: "YDR232W" RELATED Gene-based [UniProtKB:P09950]
synonym: "YD9934.16" RELATED Gene-based [UniProtKB:P09950]
synonym: "delta-ALA synthase (yeast)" EXACT [UniProtKB:P09950]
synonym: "5-aminolevulinic acid synthase (yeast)" EXACT [UniProtKB:P09950]
synonym: "delta-aminolevulinate synthase (yeast)" EXACT [UniProtKB:P09950]
xref: UniProtKB:P09950
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000003917 ! 5-aminolevulinate synthase, erythroid-specific, mitochondrial
relationship: has_gene_template SGD:S000002640 ! HEM1 (yeast)

[Term]
id: PR:P22557-4
name: 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform h4 (human)
def: "A 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22557-4." [PRO:DNx, UniProtKB:P22557]
comment: Category=organism-sequence.
synonym: "hALAS2/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P22557-4
is_a: PR:P22557 ! 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P22557-2
name: 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform h2 (human)
def: "A 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22557-2." [PRO:DNx, UniProtKB:P22557]
comment: Category=organism-sequence.
synonym: "hALAS2/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform Delta4 (human)" EXACT [UniProtKB:P22557]
xref: UniProtKB:P22557-2
is_a: PR:P22557 ! 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000039074
name: 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1
def: "A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22557-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "ALAS2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003917 ! 5-aminolevulinate synthase, erythroid-specific, mitochondrial

[Term]
id: PR:000018947
name: 5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed form
def: "A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that has had the transit peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "ALAS2/TransPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000003917 ! 5-aminolevulinate synthase, erythroid-specific, mitochondrial
intersection_of: lacks_part SO:0000725 ! transit_peptide

[Term]
id: PR:P08680-1
name: 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (mouse)
def: "A 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mALAS2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P08680-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039074 ! 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1

[Term]
id: PR:Q63147-1
name: 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (rat)
def: "A 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rALAS2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q63147-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000039074 ! 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1