[Term] id: PR:000003288 name: typical ubiquitin-conjugating enzyme E2 def: "A protein that is a stand alone version of the Ubiquitin-conjugating enzyme (Pfam:PF00179) domain. This class is called typical because it contains an essential Cys residue and hence the catalytic activity required to form a thiol-ester with ubiquitin in the second step of ubiquitination." [PRO:CNA] comment: Category=family. synonym: "UBC" BROAD [PRO:DNx] is_a: PR:000000001 ! protein