[Term]
id: PR:000003284
name: dual specificity mitogen-activated protein kinase kinase 3
def: "A dual specificity mitogen-activated protein kinase kinase 3/6 that is a translation product of the human MAP2K3 gene or a 1:1 ortholog thereof." [TLR:AMM]
comment: Category=gene. Requested by=TLR.
synonym: "MEK3" RELATED Gene-based []
synonym: "MKK3" RELATED Gene-based []
synonym: "SKK2" RELATED Gene-based []
synonym: "MEK 3" EXACT []
synonym: "MAP2K3" EXACT PRO-short-label [PRO:DNx]
synonym: "PRKMK3" RELATED Gene-based []
synonym: "MAPKK 3" EXACT []
synonym: "MAPK/ERK kinase 3" EXACT []
synonym: "MAP kinase kinase 3" EXACT []
xref: IUPHARobj:2064
is_a: PR:000021990 ! dual specificity mitogen-activated protein kinase kinase 3/6

[Term]
id: PR:O09110-1
name: dual specificity mitogen-activated protein kinase kinase 3 isoform 2 (mouse)
def: "A dual specificity mitogen-activated protein kinase kinase 3 isoform 1 that is encoded in the genome of mouse." [TLR:AMM]
comment: Category=organism-sequence.
synonym: "mMAP2K3/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "dual specificity mitogen-activated protein kinase kinase 3 isoform 3b (mouse)" EXACT [UniProtKB:O09110]
xref: UniProtKB:O09110-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000021942 ! dual specificity mitogen-activated protein kinase kinase 3 isoform 1

[Term]
id: PR:O09110-2
name: dual specificity mitogen-activated protein kinase kinase 3 isoform 1 (mouse)
def: "A dual specificity mitogen-activated protein kinase kinase 3 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mMAP2K3/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O09110-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000021944 ! dual specificity mitogen-activated protein kinase kinase 3 isoform 2

[Term]
id: PR:000049827
name: dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated 2 (mouse)
def: "A dual specificity mitogen-activated protein kinase kinase 3 isoform 2 (mouse) that has been phosphorylated at Ser-218 and Thr-222. UniProtKB:O09110-1, Ser-218, MOD:00046|Thr-222, MOD:00047." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079). Evidence=(ECO:0006055, based on PMID:21183079).
synonym: "mMAP2K3/iso:2/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O09110-1, Ser-218, MOD:00046|Thr-222, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:O09110-1 ! dual specificity mitogen-activated protein kinase kinase 3 isoform 2 (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049826
name: dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated 1 (mouse)
def: "A dual specificity mitogen-activated protein kinase kinase 3 isoform 2 (mouse) that has been phosphorylated at Ser-218. UniProtKB:O09110-1, Ser-218, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079). Evidence=(ECO:0006055, based on PMID:21183079).
synonym: "mMAP2K3/iso:2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O09110-1, Ser-218, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:O09110-1 ! dual specificity mitogen-activated protein kinase kinase 3 isoform 2 (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:O09110
name: dual specificity mitogen-activated protein kinase kinase 3 (mouse)
def: "A dual specificity mitogen-activated protein kinase kinase 3 that is encoded in the genome of mouse." [OMA:O09110, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mkk3" RELATED Gene-based [UniProtKB:O09110]
synonym: "Map2k3" RELATED Gene-based [UniProtKB:O09110]
synonym: "Prkmk3" RELATED Gene-based [UniProtKB:O09110]
synonym: "mMAP2K3" EXACT PRO-short-label [PRO:DNx]
synonym: "MEK 3 (mouse)" EXACT [UniProtKB:O09110]
synonym: "MAPKK 3 (mouse)" EXACT [UniProtKB:O09110]
synonym: "MAPK/ERK kinase 3 (mouse)" EXACT [UniProtKB:O09110]
synonym: "MAP kinase kinase 3 (mouse)" EXACT [UniProtKB:O09110]
xref: UniProtKB:O09110
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003284 ! dual specificity mitogen-activated protein kinase kinase 3
relationship: has_gene_template MGI:1346868 ! Map2k3 (mouse)