[Term]
id: PR:000003236
name: 14-3-3 protein zeta/delta
def: "A 14-3-3 protein that is a translation product of the human YWHAZ gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "SEZ-2" EXACT []
synonym: "YWHAZ" EXACT PRO-short-label [PRO:DNx]
synonym: "KCIP-1" RELATED []
synonym: "protein kinase C inhibitor protein 1" RELATED []
is_a: PR:000003237 ! 14-3-3 protein

[Term]
id: PR:000036164
name: 14-3-3 protein zeta/delta acetylated 1 (human)
def: "A 14-3-3 protein zeta/delta (human) that is N-terminal Met acetylated. Example: UniProtKB:P63104-1, Met-1, MOD:00058." [TDR:2016]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hYWHAZ/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P63104-1, Met-1, MOD:00058" NARROW PRO-proteoform-std [PRO:DNx]
xref: TDR:2016
xref: TDR:22219
is_a: PR:P63104 ! 14-3-3 protein zeta/delta (human)
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P63104-2
name: 14-3-3 protein zeta/delta isoform h2 (human)
def: "A 14-3-3 protein zeta/delta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63104-2." [PRO:DNx, UniProtKB:P63104]
comment: Category=organism-sequence.
synonym: "hYWHAZ/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P63104-2
is_a: PR:P63104 ! 14-3-3 protein zeta/delta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P63104-1
name: 14-3-3 protein zeta/delta isoform 1 (human)
def: "A 14-3-3 protein zeta/delta isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hYWHAZ/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P63104-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040069 ! 14-3-3 protein zeta/delta isoform 1

[Term]
id: PR:000044509
name: 14-3-3 protein zeta/delta unphosphorylated 1 (human)
def: "A 14-3-3 protein zeta/delta (human) that lacks phosphorylation on a Ser residue equivalent to Ser-184 in UniProtKB:P63104-1. Example: UniProtKB:P63104-1, Ser-184, PR:000026291." [PMID:15696159, PRO:CNA]
comment: Category=organism-modification. Evidence=(ECO:0000006, PMID:15696159). Note: Proteoform created based on papers selected via the eFIP text mining tool.
synonym: "hYWHAZ/UnPhos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P63104-1, Ser-184, PR:000026291" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P63104 ! 14-3-3 protein zeta/delta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000044508
name: 14-3-3 protein zeta/delta phosphorylated 1 (human)
def: "A 14-3-3 protein zeta/delta (human) that is phosphorylated on a Ser residue equivalent to Ser-184 in UniProtKB:P63104-1. Example: UniProtKB:P63104-1, Ser-184, MOD:00046." [PMID:15696159, PRO:CNA]
comment: Category=organism-modification. Evidence=(ECO:0000006, PMID:15696159). Note: Proteoform created based on papers selected via the eFIP text mining tool.
synonym: "hYWHAZ/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P63104-1, Ser-184, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P63104 ! 14-3-3 protein zeta/delta (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P63104
name: 14-3-3 protein zeta/delta (human)
def: "A 14-3-3 protein zeta/delta that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-gene.
synonym: "YWHAZ" RELATED Gene-based [UniProtKB:P63104]
synonym: "hYWHAZ" EXACT PRO-short-label [PRO:DNx]
synonym: "KCIP-1 (human)" BROAD [UniProtKB:P63104]
synonym: "protein kinase C inhibitor protein 1 (human)" BROAD [UniProtKB:P63104]
xref: Reactome:R-HSA-206099 "PR:P63104 located_in GO:0005829"
xref: Reactome:R-HSA-450469 "PR:P63104 located_in GO:0005654"
xref: Reactome:R-HSA-2457868 "PR:P63104 located_in GO:0030659"
xref: UniProtKB:P63104
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003236 ! 14-3-3 protein zeta/delta
relationship: has_gene_template HGNC:12855 ! YWHAZ (human)

[Term]
id: PR:000045851
name: 14-3-3 protein zeta/delta phosphorylated 2 (human)
def: "A 14-3-3 protein zeta/delta (human) that has been phosphorylated at the position equivalent to Ser-58 of the amino acid sequence represented by UniProtKB:P63104-1. Example: UniProtKB:P63104-1, Ser-58, MOD:00046." [PMID:11956222, PMID:12861023, PMID:16376338, iPTMnet:P63104]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:11956222, PMID:12861023, PMID:16376338). Status=unreviewed.
synonym: "hYWHAZ/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P63104-1, Ser-58, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P63104 ! 14-3-3 protein zeta/delta (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens