[Term] id: PR:000003177 name: shc-transforming protein def: "A protein that is a translation product of the human SHC1, SHC2, SHC3 or SHC4 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The canonical protein sequence has a core domain architecture consisting of a copy of the Phosphotyrosine interaction domain (PTB/PID) (Pfam:PF00640) and a copy of the SH2 domain (Pfam:PF00017) towards the C-terminus." [PRO:CNA, PRO:DAN] comment: Category=family. synonym: "SHC" EXACT [] xref: PIRSF:PIRSF038768 is_a: PR:000000001 ! protein