[Term]
id: PR:000003096
name: vascular endothelial growth factor B
def: "A protein that is a translation product of the human VEGFB gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "VRF" RELATED Gene-based []
synonym: "VEGFB" EXACT PRO-short-label [PRO:DNx]
synonym: "VEGF-B" EXACT []
synonym: "VEGF-related factor" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000003097
name: vascular endothelial growth factor B isoform 1
def: "A vascular endothelial growth factor B that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49765-1 or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=sequence.
synonym: "VEGF-B186" EXACT []
synonym: "VEGFB/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003096 ! vascular endothelial growth factor B

[Term]
id: PR:O35485
name: vascular endothelial growth factor B (rat)
def: "A vascular endothelial growth factor B that is encoded in the genome of rat." [OMA:O35485, PANTHER:PTHR12025:SF4, PRO:DNx]
comment: Category=organism-gene.
synonym: "Vrf" RELATED Gene-based [UniProtKB:O35485]
synonym: "Vegfb" RELATED Gene-based [UniProtKB:O35485]
synonym: "rVEGFB" EXACT PRO-short-label [PRO:DNx]
synonym: "VRF (rat)" EXACT [UniProtKB:O35485]
synonym: "VEGF-B (rat)" EXACT [UniProtKB:O35485]
synonym: "VEGF-related factor (rat)" EXACT [UniProtKB:O35485]
xref: UniProtKB:O35485
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000003096 ! vascular endothelial growth factor B
relationship: has_gene_template RGD:619799 ! Vegfb (rat)

[Term]
id: PR:000003100
name: vascular endothelial growth factor B isoform 1 cleaved 1
def: "A vascular endothelial growth factor B isoform 1, signal peptide removed form that contains the N-terminal cystine knot domain after proteolytic processing." [PMID:10409677, PRO:CNA]
comment: Category=modification.
synonym: "VEGFB/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000029512 ! vascular endothelial growth factor B isoform 1, signal peptide removed form
relationship: output_of GO:0016485 ! protein processing

[Term]
id: PR:O35485-2
name: vascular endothelial growth factor B isoform rVEGF-B167 (rat)
def: "A vascular endothelial growth factor B (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35485-2." [PRO:DNx, UniProtKB:O35485]
comment: Category=organism-sequence.
synonym: "rVEGFB/iso:rVEGF-B167" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O35485-2
is_a: PR:O35485 ! vascular endothelial growth factor B (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000003101
name: vascular endothelial growth factor B isoform 2
def: "A vascular endothelial growth factor B that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49765-2 or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=sequence.
synonym: "VEGF-B167" EXACT []
synonym: "VEGFB/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003096 ! vascular endothelial growth factor B

[Term]
id: PR:000056589
name: vascular endothelial growth factor B O-glycosylated 1 (human)
def: "A vascular endothelial growth factor B (human) that has been O-glycosylated at the residue equivalent to Thr-187 of the amino acid sequence represented by UniProtKB:P49765-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P49765-1, Thr-187, MOD:00005~GNO:G43417UB." [GlyGen:P49765-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hVEGFB/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P49765-1, Thr-187, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P49765 ! vascular endothelial growth factor B (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P49765-2
name: vascular endothelial growth factor B isoform VEGF-B167 (human)
def: "A vascular endothelial growth factor B isoform 2 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hVEGFB/iso:VEGF-B167" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P49765-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003101 ! vascular endothelial growth factor B isoform 2

[Term]
id: PR:P49765-1
name: vascular endothelial growth factor B isoform VEGF-B186 (human)
def: "A vascular endothelial growth factor B isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hVEGFB/iso:VEGF-B186" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P49765-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003097 ! vascular endothelial growth factor B isoform 1

[Term]
id: PR:000036636
name: vascular endothelial growth factor B isoform 1 cleaved 1 (mouse)
def: "A vascular endothelial growth factor B isoform 1 cleaved 1 in mouse. UniProtKB:P49766-1, 22-127." [PMID:10409677, PRO:CNA]
comment: Category=organism-modification.
synonym: "mVEGFB/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P49766-1, 22-127" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003100 ! vascular endothelial growth factor B isoform 1 cleaved 1

[Term]
id: PR:P49766
name: vascular endothelial growth factor B (mouse)
def: "A vascular endothelial growth factor B that is encoded in the genome of mouse." [OMA:P49766, PRO:DNx]
comment: Category=organism-gene.
synonym: "Vrf" RELATED Gene-based [UniProtKB:P49766]
synonym: "Vegfb" RELATED Gene-based [UniProtKB:P49766]
synonym: "mVEGFB" EXACT PRO-short-label [PRO:DNx]
synonym: "VRF (mouse)" EXACT [UniProtKB:P49766]
synonym: "VEGF-B (mouse)" EXACT [UniProtKB:P49766]
synonym: "VEGF-related factor (mouse)" EXACT [UniProtKB:P49766]
xref: UniProtKB:P49766
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003096 ! vascular endothelial growth factor B
relationship: has_gene_template MGI:106199 ! Vegfb (mouse)

[Term]
id: PR:P49765
name: vascular endothelial growth factor B (human)
def: "A vascular endothelial growth factor B that is encoded in the genome of human." [PRO:CNA, UniProtKB:P49765]
comment: Category=organism-gene.
synonym: "VRF" RELATED Gene-based [UniProtKB:P49765]
synonym: "VEGFB" RELATED Gene-based [UniProtKB:P49765]
synonym: "hVEGFB" EXACT PRO-short-label [PRO:DNx]
synonym: "VEGF-B (human)" EXACT [UniProtKB:P49765]
synonym: "VEGF-related factor (human)" EXACT [UniProtKB:P49765]
xref: UniProtKB:P49765
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003096 ! vascular endothelial growth factor B
relationship: has_gene_template HGNC:12681 ! VEGFB (human)

[Term]
id: PR:P49766-1
name: vascular endothelial growth factor B isoform VEGF-B186 (mouse)
def: "A vascular endothelial growth factor B isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mVEGFB/iso:VEGF-B186" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P49766-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003097 ! vascular endothelial growth factor B isoform 1

[Term]
id: PR:P49766-2
name: vascular endothelial growth factor B isoform VEGF-B167 (mouse)
def: "A vascular endothelial growth factor B isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mVEGFB/iso:VEGF-B167" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P49766-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003101 ! vascular endothelial growth factor B isoform 2

[Term]
id: PR:000029512
name: vascular endothelial growth factor B isoform 1, signal peptide removed form
def: "A vascular endothelial growth factor B isoform 1 that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "VEGFB/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000003097 ! vascular endothelial growth factor B isoform 1
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000025443
name: vascular endothelial growth factor B proteolytic cleavage product
def: "A vascular endothelial growth factor B that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "VEGFB/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000003096 ! vascular endothelial growth factor B

[Term]
id: PR:000049656
name: vascular endothelial growth factor B, signal peptide removed form (human)
def: "A vascular endothelial growth factor B (human) that has had the signal peptide removed. UniProtKB:P49765, 22-207." [PRO:DNx, Reactome:R-HSA-2975973, Reactome:R-HSA-3132756]
comment: Category=organism-modification.
synonym: "PRO_0000023398" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hVEGFB/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P49765, 22-207" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2975973 "PR:000049656 located_in GO:0005576"
xref: Reactome:R-HSA-3132756 "PR:000049656 located_in GO:0031093"
intersection_of: PR:P49765 ! vascular endothelial growth factor B (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O35485-1
name: vascular endothelial growth factor B isoform rVEGF-B186 (rat)
def: "A vascular endothelial growth factor B (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35485-1." [PRO:DNx, UniProtKB:O35485]
comment: Category=organism-sequence.
synonym: "rVEGFB/iso:rVEGF-B186" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O35485-1
is_a: PR:O35485 ! vascular endothelial growth factor B (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus