[Term]
id: PR:000003001
name: tyrosine-protein kinase Lck isoform 1 phosphorylated 1
def: "A tyrosine-protein kinase Lck isoform 1 phosphorylated form in which the phosphorylation occurs at the autoinhibitory Tyr residue (Tyr-505 in human lck), and in the activation Tyr residue (Tyr-394 in human lck). This form is predominant in the presence of HIV gp120 protein. Example: UniProtKB:P06239-1, Tyr-394/Tyr-505, MOD:00048." [PMID:9043947, PRO:CL, PRO:DAN]
comment: Category=modification.
synonym: "LCK/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "lck autoinhibited" EXACT []
is_a: PR:000003000 ! tyrosine-protein kinase Lck isoform 1 phosphorylated form
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine