[Term]
id: PR:000002334
name: mitogen-activated protein kinase 8 isoform 1
def: "A mitogen-activated protein kinase 8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P45983-2 or a 1:1 ortholog thereof." [PRO:JAN]
comment: Category=sequence.
synonym: "MAPK8/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "JNK1-alpha-1" EXACT []
is_a: PR:000002206 ! mitogen-activated protein kinase 8

[Term]
id: PR:000002335
name: mitogen-activated protein kinase 8 isoform 2
def: "A mitogen-activated protein kinase 8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P45983-1 or a 1:1 ortholog thereof." [PRO:JAN]
comment: Category=sequence.
synonym: "MAPK8/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "JNK1-alpha-2" EXACT []
is_a: PR:000002206 ! mitogen-activated protein kinase 8

[Term]
id: PR:000002206
name: mitogen-activated protein kinase 8
def: "A protein that is a translation product of the human MAPK8 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "JNK1" RELATED Gene-based []
synonym: "MAPK8" EXACT PRO-short-label [PRO:DNx]
synonym: "PRKM8" RELATED Gene-based []
synonym: "SAPK1" RELATED Gene-based []
synonym: "JNK-46" EXACT []
synonym: "MAPK 8" EXACT []
synonym: "SAPK1C" RELATED Gene-based []
synonym: "MAP kinase 8" EXACT []
synonym: "c-Jun N-terminal kinase 1" EXACT []
synonym: "stress-activated protein kinase 1" EXACT []
synonym: "stress-activated protein kinase JNK1" EXACT []
xref: IUPHARobj:1496
is_a: PR:000000001 ! protein

[Term]
id: PR:000002337
name: mitogen-activated protein kinase 8 isoform 4
def: "A mitogen-activated protein kinase 8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P45983-4 or a 1:1 ortholog thereof." [PRO:JAN]
comment: Category=sequence.
synonym: "JNK1-beta-2" EXACT []
synonym: "MAPK8/iso:4" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000002206 ! mitogen-activated protein kinase 8

[Term]
id: PR:000021993
name: mitogen-activated protein kinase 8 phosphorylated form
def: "A mitogen-activated protein kinase 8 that includes at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "MAPK8/PhosRes+" EXACT PRO-short-label [PRO:DNx]
intersection_of: has_part MOD:00696 ! phosphorylated residue
intersection_of: PR:000002206 ! mitogen-activated protein kinase 8

[Term]
id: PR:P49185
name: mitogen-activated protein kinase 8 (rat)
def: "A mitogen-activated protein kinase 8 that is encoded in the genome of rat." [OMA:P49185, PRO:DNx]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "Jnk1" RELATED Gene-based [UniProtKB:P49185]
synonym: "Mapk8" RELATED Gene-based [UniProtKB:P49185]
synonym: "Prkm8" RELATED Gene-based [UniProtKB:P49185]
synonym: "rMAPK8" EXACT PRO-short-label [PRO:DNx]
synonym: "MAPK 8 (rat)" EXACT [UniProtKB:P49185]
synonym: "p54 gamma (rat)" EXACT [UniProtKB:P49185]
synonym: "SAPK gamma (rat)" EXACT [UniProtKB:P49185]
synonym: "MAP kinase 8 (rat)" EXACT [UniProtKB:P49185]
synonym: "c-Jun N-terminal kinase 1 (rat)" EXACT [UniProtKB:P49185]
synonym: "stress-activated protein kinase JNK1 (rat)" EXACT [UniProtKB:P49185]
xref: UniProtKB:P49185
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000002206 ! mitogen-activated protein kinase 8
relationship: has_gene_template RGD:621506 ! Mapk8 (rat)

[Term]
id: PR:000021982
name: mitogen-activated protein kinase 8 phosphorylated 1
def: "A mitogen-activated protein kinase 8 phosphorylated form in which the phosphorylation occurs at the TxY motif that activates the MAP kinases." [PMID:16212907, TLR:AMM]
comment: Category=modification. Requested by=TLR.
synonym: "MAPK8/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000021993 ! mitogen-activated protein kinase 8 phosphorylated form

[Term]
id: PR:Q91Y86
name: mitogen-activated protein kinase 8 (mouse)
def: "A mitogen-activated protein kinase 8 that is encoded in the genome of mouse." [OMA:Q91Y86, PRO:DNx]
comment: Category=organism-gene.
synonym: "Jnk1" RELATED Gene-based [UniProtKB:Q91Y86]
synonym: "Mapk8" RELATED Gene-based [UniProtKB:Q91Y86]
synonym: "Prkm8" RELATED Gene-based [UniProtKB:Q91Y86]
synonym: "mMAPK8" EXACT PRO-short-label [PRO:DNx]
synonym: "MAPK 8 (mouse)" EXACT [UniProtKB:Q91Y86]
synonym: "MAP kinase 8 (mouse)" EXACT [UniProtKB:Q91Y86]
synonym: "c-Jun N-terminal kinase 1 (mouse)" EXACT [UniProtKB:Q91Y86]
synonym: "stress-activated protein kinase JNK1 (mouse)" EXACT [UniProtKB:Q91Y86]
xref: UniProtKB:Q91Y86
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002206 ! mitogen-activated protein kinase 8
relationship: has_gene_template MGI:1346861 ! Mapk8 (mouse)

[Term]
id: PR:P45983
name: mitogen-activated protein kinase 8 (human)
def: "A mitogen-activated protein kinase 8 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P45983]
comment: Category=organism-gene.
synonym: "JNK1" RELATED Gene-based [UniProtKB:P45983]
synonym: "MAPK8" RELATED Gene-based [UniProtKB:P45983]
synonym: "PRKM8" RELATED Gene-based [UniProtKB:P45983]
synonym: "SAPK1" RELATED Gene-based [UniProtKB:P45983]
synonym: "SAPK1C" RELATED Gene-based [UniProtKB:P45983]
synonym: "hMAPK8" EXACT PRO-short-label [PRO:DNx]
synonym: "JNK-46 (human)" EXACT [UniProtKB:P45983]
synonym: "MAPK 8 (human)" EXACT [UniProtKB:P45983]
synonym: "MAP kinase 8 (human)" EXACT [UniProtKB:P45983]
synonym: "c-Jun N-terminal kinase 1 (human)" EXACT [UniProtKB:P45983]
synonym: "stress-activated protein kinase 1c (human)" EXACT [UniProtKB:P45983]
synonym: "stress-activated protein kinase JNK1 (human)" EXACT [UniProtKB:P45983]
xref: Reactome:R-HSA-168141 "PR:P45983 located_in GO:0005829"
xref: DTO:03100320
xref: UniProtKB:P45983
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002206 ! mitogen-activated protein kinase 8
relationship: has_gene_template HGNC:6881 ! MAPK8 (human)

[Term]
id: PR:000002336
name: mitogen-activated protein kinase 8 isoform 3
def: "A mitogen-activated protein kinase 8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P45983-3 or a 1:1 ortholog thereof." [PRO:JAN]
comment: Category=sequence.
synonym: "JNK1-beta-1" EXACT []
synonym: "MAPK8/iso:3" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000002206 ! mitogen-activated protein kinase 8

[Term]
id: PR:Q7TSJ7
name: mitogen-activated protein kinase isoform 2 (mouse)
def: "A mitogen-activated protein kinase 8 isoform 2 that is encoded in the genome of mouse." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "mMAPK8/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q7TSJ7
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002335 ! mitogen-activated protein kinase 8 isoform 2

[Term]
id: PR:P45983-4
name: mitogen-activated protein kinase 8 isoform 4 (human)
def: "A mitogen-activated protein kinase 8 isoform 4 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hMAPK8/iso:4" EXACT PRO-short-label [PRO:DNx]
synonym: "mitogen-activated protein kinase 8 isoform JNK1-beta-2 (human)" EXACT [UniProtKB:P45983]
xref: UniProtKB:P45983-4
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002337 ! mitogen-activated protein kinase 8 isoform 4

[Term]
id: PR:P45983-5
name: mitogen-activated protein kinase 8 isoform h5 (human)
def: "A mitogen-activated protein kinase 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P45983-5." [PRO:DNx, UniProtKB:P45983]
comment: Category=organism-sequence.
synonym: "hMAPK8/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P45983-5
is_a: PR:P45983 ! mitogen-activated protein kinase 8 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:A6P3E4
name: mitogen-activated protein kinase isoform 3 (mouse)
def: "A mitogen-activated protein kinase 8 isoform 3 that is encoded in the genome of mouse." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "mMAPK8/iso:3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:A6P3E4
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002336 ! mitogen-activated protein kinase 8 isoform 3

[Term]
id: PR:Q91Y86-1
name: mitogen-activated protein kinase 8 isoform 1 (mouse)
def: "A mitogen-activated protein kinase 8 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "mMAPK8/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q91Y86-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002334 ! mitogen-activated protein kinase 8 isoform 1

[Term]
id: PR:P45983-1
name: mitogen-activated protein kinase 8 isoform 2 (human)
def: "A mitogen-activated protein kinase 8 isoform 2 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hMAPK8/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "mitogen-activated protein kinase 8 isoform JNK1-alpha-2 (human)" EXACT [UniProtKB:P45983]
xref: UniProtKB:P45983-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002335 ! mitogen-activated protein kinase 8 isoform 2

[Term]
id: PR:P45983-3
name: mitogen-activated protein kinase 8 isoform 3 (human)
def: "A mitogen-activated protein kinase 8 isoform 3 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hMAPK8/iso:3" EXACT PRO-short-label [PRO:DNx]
synonym: "mitogen-activated protein kinase 8 isoform JNK1-beta-1 (human)" EXACT [UniProtKB:P45983]
xref: UniProtKB:P45983-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002336 ! mitogen-activated protein kinase 8 isoform 3

[Term]
id: PR:P45983-2
name: mitogen-activated protein kinase 8 isoform 1 (human)
def: "A mitogen-activated protein kinase 8 isoform 1 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hMAPK8/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "mitogen-activated protein kinase 8 isoform JNK1-alpha-1 (human)" EXACT [UniProtKB:P45983]
xref: UniProtKB:P45983-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002334 ! mitogen-activated protein kinase 8 isoform 1