[Term]
id: PR:Q07812-8
name: apoptosis regulator BAX isoform sigma (human)
def: "An apoptosis regulator BAX isoform 8 that is encoded in the genome of human." [PRO:SY]
comment: Category=organism-sequence.
synonym: "hBAX/iso:sigma" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q07812-8
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002306 ! apoptosis regulator BAX isoform 8

[Term]
id: PR:Q07812-7
name: apoptosis regulator BAX isoform psi (human)
def: "An apoptosis regulator BAX isoform 7 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
comment: Category=organism-sequence.
synonym: "hBAX/iso:psi" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q07812-7
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002305 ! apoptosis regulator BAX isoform 7

[Term]
id: PR:Q07812-6
name: apoptosis regulator BAX isoform zeta (human)
def: "An apoptosis regulator BAX isoform 6 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
comment: Category=organism-sequence.
synonym: "hBAX/iso:zeta" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q07812-6
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002304 ! apoptosis regulator BAX isoform 6

[Term]
id: PR:Q07812-5
name: apoptosis regulator BAX isoform epsilon (human)
def: "An apoptosis regulator BAX isoform 5 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
comment: Category=organism-sequence.
synonym: "hBAX/iso:epsilon" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q07812-5
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002303 ! apoptosis regulator BAX isoform 5

[Term]
id: PR:Q07812-4
name: apoptosis regulator BAX isoform delta (human)
def: "An apoptosis regulator BAX isoform 4 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
comment: Category=organism-sequence.
synonym: "hBAX/iso:delta" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q07812-4
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002302 ! apoptosis regulator BAX isoform 4

[Term]
id: PR:Q07812-3
name: apoptosis regulator BAX isoform gamma (human)
def: "An apoptosis regulator BAX isoform 3 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
comment: Category=organism-sequence.
synonym: "hBAX/iso:gamma" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q07812-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002301 ! apoptosis regulator BAX isoform 3

[Term]
id: PR:Q07812-2
name: apoptosis regulator BAX isoform beta (human)
def: "An apoptosis regulator BAX isoform 2 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
comment: Category=organism-sequence.
synonym: "hBAX/iso:beta" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q07812-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002300 ! apoptosis regulator BAX isoform 2

[Term]
id: PR:Q07812-1
name: apoptosis regulator BAX isoform alpha (human)
def: "An apoptosis regulator BAX isoform 1 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
comment: Category=organism-sequence.
synonym: "hBAX/iso:alpha" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q07812-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002299 ! apoptosis regulator BAX isoform 1

[Term]
id: PR:Q07812
name: apoptosis regulator BAX (human)
def: "An apoptosis regulator BAX that is encoded in the genome of human." [PRO:SY, UniProtKB:Q07812]
comment: Category=organism-gene.
synonym: "BAX" RELATED Gene-based [UniProtKB:Q07812]
synonym: "hBAX" EXACT PRO-short-label [PRO:DNx]
synonym: "BCL2L4" RELATED Gene-based [UniProtKB:Q07812]
synonym: "Bcl2-L-4 (human)" EXACT [UniProtKB:Q07812]
synonym: "Bcl-2-like protein 4 (human)" EXACT [UniProtKB:Q07812]
xref: UniProtKB:Q07812
xref: Reactome:R-HSA-139907 "PR:Q07812 located_in GO:0005829"
xref: Reactome:R-HSA-139916 "PR:Q07812 located_in GO:0005829"
xref: Reactome:R-HSA-139949 "PR:Q07812 located_in GO:0005741"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002193 ! apoptosis regulator BAX
relationship: has_gene_template HGNC:959 ! BAX (human)

[Term]
id: PR:000002193
name: apoptosis regulator BAX
def: "A protein that is a translation product of the human BAX gene or a 1:1 ortholog thereof. In this class the Bcl-2 domain is characterized by the presence of the BH3, BH1, and BH2 motifs." [PRO:SY, PRO:WCB]
comment: Category=gene.
synonym: "BAX" EXACT PRO-short-label [PRO:DNx]
synonym: "BCL2L4" RELATED Gene-based []
synonym: "Bcl2-L-4" EXACT []
synonym: "Bcl-2-like protein 4" EXACT []
xref: PIRSF:PIRSF038828
is_a: PR:000000001 ! protein

[Term]
id: PR:000036214
name: apoptosis regulator BAX acetylated 1 (human)
def: "An apoptosis regulator BAX (human) that is N-terminal Met acetylated. Example: UniProtKB:Q07812-1, Met-1, MOD:00058." [TDR:1457]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hBAX/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q07812-1, Met-1, MOD:00058" NARROW PRO-proteoform-std [PRO:DNx]
xref: TDR:1457
xref: TDR:17995
is_a: PR:Q07812 ! apoptosis regulator BAX (human)
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045886
name: apoptosis regulator BAX phosphorylated 1 (human)
def: "An apoptosis regulator BAX (human) that has been phosphorylated at the position equivalent to Thr-167 of the amino acid sequence represented by UniProtKB:Q07812-1. Example: UniProtKB:Q07812-1, Thr-167, MOD:00047." [PMID:19182807, iPTMnet:Q07812]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:19182807). Status=unreviewed.
synonym: "hBAX/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q07812-1, Thr-167, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q07812 ! apoptosis regulator BAX (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens