[Term] id: PR:P14316 name: interferon regulatory factor 2 (human) def: "An interferon regulatory factor 2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P14316] comment: Category=organism-gene. synonym: "IRF2" RELATED Gene-based [UniProtKB:P14316] synonym: "hIRF2" EXACT PRO-short-label [PRO:DNx] synonym: "IRF-2 (human)" EXACT [UniProtKB:P14316] xref: Reactome:R-HSA-994031 "PR:P14316 located_in GO:0005654" xref: Reactome:R-HSA-1015681 "PR:P14316 located_in GO:0005829" xref: UniProtKB:P14316 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000002044 ! interferon regulatory factor 2 relationship: has_gene_template HGNC:6117 ! IRF2 (human) [Term] id: PR:000002044 name: interferon regulatory factor 2 def: "An interferon regulatory factor 1/2 that is a translation product of the human IRF2 gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. synonym: "IRF2" EXACT PRO-short-label [PRO:DNx] synonym: "IRF-2" EXACT [] is_a: PR:000001862 ! interferon regulatory factor 1/2 [Term] id: PR:P23906 name: interferon regulatory factor 2 (mouse) def: "An interferon regulatory factor 2 that is encoded in the genome of mouse." [OMA:P23906, PRO:DNx] comment: Category=organism-gene. synonym: "Irf2" RELATED Gene-based [UniProtKB:P23906] synonym: "mIRF2" EXACT PRO-short-label [PRO:DNx] synonym: "IRF-2 (mouse)" EXACT [UniProtKB:P23906] xref: UniProtKB:P23906 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000002044 ! interferon regulatory factor 2 relationship: has_gene_template MGI:96591 ! Irf2 (mouse) [Term] id: PR:000028810 name: interferon regulatory factor 2 isoform 1 def: "An interferon regulatory factor 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14316-1 or a 1:1 ortholog thereof." [PMID:12738767, PRO:PD] comment: Category=sequence. synonym: "IRF2/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000002044 ! interferon regulatory factor 2 [Term] id: PR:000028813 name: interferon regulatory factor 2 isoform 1 acetylated 1 (human) def: "An interferon regulatory factor 2 isoform 1 acetylated 1 in human. UniProtKB:P14316-1, Lys-75/Lys-78, MOD:00064." [PMID:12738767, PRO:PD] comment: Category=organism-modification. synonym: "hIRF2/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P14316-1, Lys-75/Lys-78, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028812 ! interferon regulatory factor 2 isoform 1 acetylated 1 relationship: has_part MOD:00064 ! N6-acetyl-L-lysine [Term] id: PR:000028812 name: interferon regulatory factor 2 isoform 1 acetylated 1 def: "An interferon regulatory factor 2 isoform 1 that has been acetylated at the two Lys residues in the motif PKTWKA located in IRF (Pfam:PF00605) domain. Example: UniProtKB:P14316-1, Lys-75/Lys-78, MOD:00064." [PMID:12738767, PRO:PD] comment: Category=modification. Acetylase=("EP300"; PR:000007102). Acetylase=("KAT2B"; PR:000012332). synonym: "IRF2/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000028810 ! interferon regulatory factor 2 isoform 1 relationship: has_part MOD:00064 ! N6-acetyl-L-lysine [Term] id: PR:Q98925 name: interferon regulatory factor 2 (chicken) def: "An interferon regulatory factor 2 that is encoded in the genome of chicken." [OMA:Q98925, PANTHER:PTHR11949:SF3, PRO:DNx] comment: Category=organism-gene. synonym: "IRF2" RELATED Gene-based [UniProtKB:Q98925] synonym: "chick-IRF2" EXACT PRO-short-label [PRO:DNx] synonym: "IRF-2 (chicken)" EXACT [UniProtKB:Q98925] xref: UniProtKB:Q98925 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000002044 ! interferon regulatory factor 2 relationship: has_gene_template NCBIGene:396115 ! IRF2 (chicken) [Term] id: PR:P14316-2 name: interferon regulatory factor 2 isoform h2 (human) def: "An interferon regulatory factor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14316-2." [PRO:DNx, UniProtKB:P14316] comment: Category=organism-sequence. synonym: "hIRF2/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "interferon regulatory factor 2 isoform IRF-2s (human)" EXACT [UniProtKB:P14316] synonym: "interferon regulatory factor 2 isoform IRF-2[S] (human)" EXACT [UniProtKB:P14316] xref: UniProtKB:P14316-2 is_a: PR:P14316 ! interferon regulatory factor 2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P14316-1 name: interferon regulatory factor 2 isoform 1 (human) def: "An interferon regulatory factor 2 isoform 1 that is encoded in the genome of human." [PRO:PD] comment: Category=organism-sequence. synonym: "hIRF2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P14316-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028810 ! interferon regulatory factor 2 isoform 1