[Term]
id: PR:Q03267
name: DNA-binding protein Ikaros (mouse)
def: "A DNA-binding protein Ikaros that is encoded in the genome of mouse." [OMA:Q03267, PRO:DNx]
comment: Category=organism-gene.
synonym: "Lyf1" RELATED Gene-based [UniProtKB:Q03267]
synonym: "Ikzf1" RELATED Gene-based [UniProtKB:Q03267]
synonym: "Ikaros" RELATED Gene-based [UniProtKB:Q03267]
synonym: "mIKZF1" EXACT PRO-short-label [PRO:DNx]
synonym: "Zfpn1a1" RELATED Gene-based [UniProtKB:Q03267]
synonym: "Znfn1a1" RELATED Gene-based [UniProtKB:Q03267]
synonym: "Ikaros family zinc finger protein 1 (mouse)" EXACT [UniProtKB:Q03267]
synonym: "lymphoid transcription factor LyF-1 (mouse)" EXACT [UniProtKB:Q03267]
xref: UniProtKB:Q03267
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001811 ! DNA-binding protein Ikaros
relationship: has_gene_template MGI:1342540 ! Ikzf1 (mouse)

[Term]
id: PR:000018260
name: DNA-binding protein Ikaros isoform 1 phosphorylated 1
def: "A DNA-binding protein Ikaros isoform 1 phosphorylated form in which the phosphorylation occurs within the serine/threonine-rich conserved region (p1)." [PMID:15024069]
comment: Category=modification.
synonym: "IKZF1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000018259 ! DNA-binding protein Ikaros isoform 1 phosphorylated form
relationship: has_part MOD:00696 ! phosphorylated residue

[Term]
id: PR:000001811
name: DNA-binding protein Ikaros
def: "An Ikaros-like zinc finger transcription factor that is a translation product of the human IKZF1 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "IK1" RELATED Gene-based []
synonym: "LYF1" RELATED Gene-based []
synonym: "IKZF1" EXACT PRO-short-label [PRO:DNx]
synonym: "IKAROS" RELATED Gene-based []
synonym: "ZNFN1A1" RELATED Gene-based []
synonym: "Zfpn1a1" RELATED Gene-based []
synonym: "Ikaros family zinc finger protein 1" EXACT []
synonym: "lymphoid transcription factor LyF-1" EXACT []
is_a: PR:000002986 ! Ikaros-like zinc finger transcription factor

[Term]
id: PR:O42410
name: DNA-binding protein Ikaros (chicken)
def: "A DNA-binding protein Ikaros that is encoded in the genome of chicken." [OMA:O42410, PRO:DNx]
comment: Category=organism-gene.
synonym: "IK" RELATED Gene-based [UniProtKB:O42410]
synonym: "IKZF1" RELATED Gene-based [UniProtKB:O42410]
synonym: "IKAROS" RELATED Gene-based [UniProtKB:O42410]
synonym: "ZNFN1A1" RELATED Gene-based [UniProtKB:O42410]
synonym: "chick-IKZF1" EXACT PRO-short-label [PRO:DNx]
synonym: "Ikaros family zinc finger protein 1 (chicken)" EXACT [UniProtKB:O42410]
xref: UniProtKB:O42410
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000001811 ! DNA-binding protein Ikaros
relationship: has_gene_template NCBIGene:395974 ! IKZF1 (chicken)

[Term]
id: PR:Q13422-8
name: DNA-binding protein Ikaros isoform Ikx (human)
def: "A DNA-binding protein Ikaros (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13422-8." [PRO:DNx, UniProtKB:Q13422]
comment: Category=organism-sequence.
synonym: "hIKZF1/iso:Ikx" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13422-8
is_a: PR:Q13422 ! DNA-binding protein Ikaros (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13422-3
name: DNA-binding protein Ikaros isoform hIk3 (human)
def: "A DNA-binding protein Ikaros (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13422-3." [PRO:DNx, UniProtKB:Q13422]
comment: Category=organism-sequence.
synonym: "hIKZF1/iso:hIk3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13422-3
is_a: PR:Q13422 ! DNA-binding protein Ikaros (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13422-2
name: DNA-binding protein Ikaros isoform Ik2 (human)
def: "A DNA-binding protein Ikaros isoform 6 that is encoded in the genome of human." [PRO:HJD]
comment: Category=organism-sequence.
synonym: "hIKZF1/iso:Ik2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13422-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002155 ! DNA-binding protein Ikaros isoform 6

[Term]
id: PR:Q13422-1
name: DNA-binding protein Ikaros isoform Ik1 (human)
def: "A DNA-binding protein Ikaros isoform 1 that is encoded in the genome of human." [PRO:HJD]
comment: Category=organism-sequence.
synonym: "hIKZF1/iso:Ik1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13422-1
xref: Reactome:R-HSA-9017118 "PR:Q13422-1 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002150 ! DNA-binding protein Ikaros isoform 1

[Term]
id: PR:Q13422-7
name: DNA-binding protein Ikaros isoform hIk7 (human)
def: "A DNA-binding protein Ikaros (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13422-7." [PRO:DNx, UniProtKB:Q13422]
comment: Category=organism-sequence.
synonym: "hIKZF1/iso:hIk7" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13422-7
is_a: PR:Q13422 ! DNA-binding protein Ikaros (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13422-6
name: DNA-binding protein Ikaros isoform Ik6 (human)
def: "A DNA-binding protein Ikaros isoform 2 that is encoded in the genome of human." [PRO:HJD]
comment: Category=organism-sequence.
synonym: "hIKZF1/iso:Ik6" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13422-6
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002151 ! DNA-binding protein Ikaros isoform 2

[Term]
id: PR:Q13422-5
name: DNA-binding protein Ikaros isoform Ik5 (human)
def: "A DNA-binding protein Ikaros isoform 4 that is encoded in the genome of human." [PRO:HJD]
comment: Category=organism-sequence.
synonym: "hIKZF1/iso:Ik5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13422-5
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002153 ! DNA-binding protein Ikaros isoform 4

[Term]
id: PR:Q13422-4
name: DNA-binding protein Ikaros isoform hIk4 (human)
def: "A DNA-binding protein Ikaros (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13422-4." [PRO:DNx, UniProtKB:Q13422]
comment: Category=organism-sequence.
synonym: "hIKZF1/iso:hIk4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13422-4
is_a: PR:Q13422 ! DNA-binding protein Ikaros (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q03267-5
name: DNA-binding protein Ikaros isoform IV (mouse)
def: "A DNA-binding protein Ikaros isoform 5 that is encoded in the genome of mouse." [PRO:HJD]
comment: Category=organism-sequence.
synonym: "mIKZF1/iso:IV" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q03267-5
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002154 ! DNA-binding protein Ikaros isoform 5

[Term]
id: PR:000018259
name: DNA-binding protein Ikaros isoform 1 phosphorylated form
def: "A DNA-binding protein Ikaros isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "IKZF1/iso:1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
intersection_of: has_part MOD:00696 ! phosphorylated residue
intersection_of: PR:000002150 ! DNA-binding protein Ikaros isoform 1

[Term]
id: PR:Q13422
name: DNA-binding protein Ikaros (human)
def: "A DNA-binding protein Ikaros that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q13422]
comment: Category=organism-gene.
synonym: "IK1" RELATED Gene-based [UniProtKB:Q13422]
synonym: "LYF1" RELATED Gene-based [UniProtKB:Q13422]
synonym: "IKZF1" RELATED Gene-based [UniProtKB:Q13422]
synonym: "IKAROS" RELATED Gene-based [UniProtKB:Q13422]
synonym: "hIKZF1" EXACT PRO-short-label [PRO:DNx]
synonym: "ZNFN1A1" RELATED Gene-based [UniProtKB:Q13422]
synonym: "Ikaros family zinc finger protein 1 (human)" EXACT [UniProtKB:Q13422]
synonym: "lymphoid transcription factor LyF-1 (human)" EXACT [UniProtKB:Q13422]
xref: UniProtKB:Q13422
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001811 ! DNA-binding protein Ikaros
relationship: has_gene_template HGNC:13176 ! IKZF1 (human)

[Term]
id: PR:Q03267-4
name: DNA-binding protein Ikaros isoform III (mouse)
def: "A DNA-binding protein Ikaros isoform 4 that is encoded in the genome of mouse." [PRO:HJD]
comment: Category=organism-sequence.
synonym: "mIKZF1/iso:III" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q03267-4
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002153 ! DNA-binding protein Ikaros isoform 4

[Term]
id: PR:Q03267-6
name: DNA-binding protein Ikaros isoform V (mouse)
def: "A DNA-binding protein Ikaros isoform 6 that is encoded in the genome of mouse." [PRO:HJD]
comment: Category=organism-sequence.
synonym: "mIKZF1/iso:V" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q03267-6
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002155 ! DNA-binding protein Ikaros isoform 6

[Term]
id: PR:Q03267-1
name: DNA-binding protein Ikaros isoform VI (mouse)
def: "A DNA-binding protein Ikaros isoform 1 that is encoded in the genome of mouse." [PRO:HJD]
comment: Category=organism-sequence.
synonym: "mIKZF1/iso:VI" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q03267-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002150 ! DNA-binding protein Ikaros isoform 1

[Term]
id: PR:000002150
name: DNA-binding protein Ikaros isoform 1
def: "A DNA-binding protein Ikaros that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03267-1 or a 1:1 ortholog thereof." [PRO:HJD]
comment: Category=sequence.
synonym: "IKZF1/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "DNA-binding protein Ikaros isoform VI" EXACT []
synonym: "DNA-binding protein Ikaros isoform Ik1" EXACT []
is_a: PR:000001811 ! DNA-binding protein Ikaros

[Term]
id: PR:000002151
name: DNA-binding protein Ikaros isoform 2
def: "A DNA-binding protein Ikaros that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03267-2 or a 1:1 ortholog thereof." [PMID:18623087, PMID:8895580, PRO:DAN, PRO:HJD]
comment: Category=sequence. Note: This isoform lacks four N-terminal zinc finger domains in comparison to isoform 1, thus functioning as a dominant negative.
synonym: "IKZF1/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "DNA-binding protein Ikaros isoform Ik6" EXACT []
is_a: PR:000001811 ! DNA-binding protein Ikaros

[Term]
id: PR:000002152
name: DNA-binding protein Ikaros isoform 3
def: "A DNA-binding protein Ikaros that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03267-3 or a 1:1 ortholog thereof." [PRO:HJD]
comment: Category=sequence.
synonym: "IKZF1/iso:3" EXACT PRO-short-label [PRO:DNx]
synonym: "DNA-binding protein Ikaros isoform II" EXACT []
is_a: PR:000001811 ! DNA-binding protein Ikaros

[Term]
id: PR:000002153
name: DNA-binding protein Ikaros isoform 4
def: "A DNA-binding protein Ikaros that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03267-4 or a 1:1 ortholog thereof." [PMID:11781232, PRO:DAN, PRO:HJD]
comment: Category=sequence.
synonym: "IKZF1/iso:4" EXACT PRO-short-label [PRO:DNx]
synonym: "DNA-binding protein Ikaros isoform III" EXACT []
synonym: "DNA-binding protein Ikaros isoform Ik5" EXACT []
is_a: PR:000001811 ! DNA-binding protein Ikaros

[Term]
id: PR:000002154
name: DNA-binding protein Ikaros isoform 5
def: "A DNA-binding protein Ikaros that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03267-5 or a 1:1 ortholog thereof." [PRO:HJD]
comment: Category=sequence.
synonym: "IKZF1/iso:5" EXACT PRO-short-label [PRO:DNx]
synonym: "DNA-binding protein Ikaros isoform IV" EXACT []
is_a: PR:000001811 ! DNA-binding protein Ikaros

[Term]
id: PR:000002155
name: DNA-binding protein Ikaros isoform 6
def: "A DNA-binding protein Ikaros that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03267-6 or a 1:1 ortholog thereof." [PMID:1439790, PMID:8964602, PRO:HJD]
comment: Category=sequence.
synonym: "IKZF1/iso:6" EXACT PRO-short-label [PRO:DNx]
synonym: "DNA-binding protein Ikaros isoform V" EXACT []
synonym: "DNA-binding protein Ikaros isoform Ik2" EXACT []
is_a: PR:000001811 ! DNA-binding protein Ikaros

[Term]
id: PR:Q03267-3
name: DNA-binding protein Ikaros isoform II (mouse)
def: "A DNA-binding protein Ikaros isoform 3 that is encoded in the genome of mouse." [PRO:HJD]
comment: Category=organism-sequence.
synonym: "mIKZF1/iso:II" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q03267-3
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002152 ! DNA-binding protein Ikaros isoform 3

[Term]
id: PR:Q03267-2
name: DNA-binding protein Ikaros isoform I (mouse)
def: "A DNA-binding protein Ikaros isoform 2 that is encoded in the genome of mouse." [PRO:HJD]
comment: Category=organism-sequence.
synonym: "mIKZF1/iso:I" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q03267-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002151 ! DNA-binding protein Ikaros isoform 2

[Term]
id: PR:O42410-1
name: DNA-binding protein Ikaros isoform 1 (chicken)
def: "A DNA-binding protein Ikaros (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O42410-1." [PRO:DNx, UniProtKB:O42410]
comment: Category=organism-sequence.
synonym: "chick-IKZF1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O42410-1
is_a: PR:O42410 ! DNA-binding protein Ikaros (chicken)
relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus