[Term]
id: PR:000001471
name: interleukin-10
def: "A class 2 cytokine, IL-10 type that is a translation product of the human IL10 gene or a 1:1 ortholog thereof. Active interleukin-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T cells. Structurally, IL-10 is a protein of about 160 amino acids that contains four conserved cysteines involved in disulfide bonds." [PANTHER:PTHR11585:SF1, PRO:JAN]
comment: Category=gene.
synonym: "CSIF" EXACT []
synonym: "IL10" EXACT PRO-short-label [PRO:DNx]
synonym: "IL-10" EXACT []
synonym: "cytokine synthesis inhibitory factor" EXACT []
xref: PANTHER:PTHR11585:SF1
is_a: PR:000001335 ! class 2 cytokine, IL-10 type