[Term]
id: PR:P15260
name: interferon gamma receptor 1 (human)
def: "An interferon gamma receptor alpha chain that is encoded in the genome of human." [PRO:WCB, UniProtKB:P15260]
comment: Category=organism-gene.
synonym: "IFNGR1" RELATED Gene-based [UniProtKB:P15260]
synonym: "hIFNGR1" EXACT PRO-short-label [PRO:DNx]
synonym: "CD119 (human)" EXACT [UniProtKB:P15260]
synonym: "CDw119 (human)" EXACT [UniProtKB:P15260]
synonym: "IFN-gamma-R1 (human)" EXACT [UniProtKB:P15260]
synonym: "IFN-gamma-R-alpha (human)" EXACT [UniProtKB:P15260]
synonym: "IFN-gamma receptor 1 (human)" EXACT [UniProtKB:P15260]
synonym: "interferon gamma receptor alpha-chain (human)" EXACT [UniProtKB:P15260]
xref: UniProtKB:P15260
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001361 ! interferon gamma receptor alpha chain
relationship: has_gene_template HGNC:5439 ! IFNGR1 (human)

[Term]
id: PR:P15260-2
name: interferon gamma receptor 1 isoform h2 (human)
def: "An interferon gamma receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15260-2." [PRO:DNx, UniProtKB:P15260]
comment: Category=organism-sequence.
synonym: "hIFNGR1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P15260-2
is_a: PR:P15260 ! interferon gamma receptor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P15260-1
name: interferon gamma receptor 1 isoform h1 (human)
def: "An interferon gamma receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15260-1." [PRO:DNx, UniProtKB:P15260]
comment: Category=organism-sequence.
synonym: "hIFNGR1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P15260-1
is_a: PR:P15260 ! interferon gamma receptor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000001361
name: interferon gamma receptor alpha chain
def: "A protein that is a translation product of the human IFNGR1 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "CD119" EXACT []
synonym: "Ifngr" RELATED Gene-based []
synonym: "CDw119" EXACT []
synonym: "IFNGR1" EXACT PRO-short-label [PRO:DNx]
synonym: "IFN-gamma-R1" EXACT []
synonym: "IFN-gamma-R-alpha" EXACT []
synonym: "IFN-gamma receptor 1" EXACT []
synonym: "interferon gamma receptor alpha-chain" EXACT []
xref: IUPHARobj:1725
xref: PANTHER:PTHR20859:SF5
is_a: PR:000000001 ! protein

[Term]
id: PR:000047964
name: interferon gamma receptor 1, signal peptide removed form (human)
def: "An interferon gamma receptor 1 (human) that has had the signal peptide removed. UniProtKB:P15260, 18-489." [PRO:DNx, Reactome:R-HSA-629623]
comment: Category=organism-modification.
synonym: "PRO_0000011009" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hIFNGR1/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P15260, 18-489" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-629623 "PR:000047964 located_in GO:0005886"
intersection_of: PR:P15260 ! interferon gamma receptor 1 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047965
name: interferon gamma receptor 1, signal peptide removed phosphorylated 1 (human)
def: "An interferon gamma receptor 1 (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at position 457 of the amino acid sequence represented by UniProtKB:P15260. UniProtKB:P15260, 18-489, Tyr-457, MOD:00048." [PRO:DAN, Reactome:R-HSA-873798]
comment: Category=organism-modification. Note: The modified site indicated here (Tyr-457) is referred to as Tyr-440 in the literature (Y440, accounting for signal peptide removal). [PRO:DAN]
synonym: "hIFNGR1/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000011009, Tyr-457, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DAN]
synonym: "UniProtKB:P15260, 18-489, Tyr-457, MOD:00048" EXACT PRO-proteoform-std [PRO:DAN]
xref: Reactome:R-HSA-873798 "PR:000047965 located_in GO:0005886"
is_a: PR:P15260 ! interferon gamma receptor 1 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part SO:0000418 ! signal_peptide