[Term]
id: PR:000001013
name: integrin alpha-X
def: "An integrin alpha with A domain that is a translation product of the human ITGAX gene or a 1:1 ortholog thereof. Integrin alpha-X complexed with beta-2 is a receptor for fibrinogen. It recognizes the sequence GPR in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis." [UniProtKB:P20702]
comment: Category=gene. Requested by=CL.
synonym: "CD11C" RELATED Gene-based []
synonym: "CD11c" EXACT []
synonym: "ITGAX" EXACT PRO-short-label [PRO:DNx]
synonym: "Leu M5" EXACT []
synonym: "CD11 antigen-like family member C" EXACT []
synonym: "leukocyte adhesion receptor p150,95" EXACT []
synonym: "leukocyte adhesion glycoprotein p150,95 alpha chain" EXACT []
xref: IUPHARobj:2454
is_a: PR:000001005 ! integrin alpha with A domain

[Term]
id: PR:Q9QXH4
name: integrin alpha-X (mouse)
def: "An integrin alpha-X that is encoded in the genome of mouse." [OMA:Q9QXH4, PRO:DNx]
comment: Category=organism-gene.
synonym: "Itgax" RELATED Gene-based [UniProtKB:Q9QXH4]
synonym: "mITGAX" EXACT PRO-short-label [PRO:DNx]
synonym: "CD11c (mouse)" EXACT [UniProtKB:Q9QXH4]
synonym: "CD11 antigen-like family member C (mouse)" EXACT [UniProtKB:Q9QXH4]
synonym: "leukocyte adhesion receptor p150,95 (mouse)" EXACT [UniProtKB:Q9QXH4]
synonym: "leukocyte adhesion glycoprotein p150,95 alpha chain (mouse)" EXACT [UniProtKB:Q9QXH4]
xref: UniProtKB:Q9QXH4
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001013 ! integrin alpha-X
relationship: has_gene_template MGI:96609 ! Itgax (mouse)