[Term]
id: PR:000001002
name: CD19 molecule
def: "A protein that is a translation product of the human CD19 gene or a 1:1 ortholog thereof. It is composed of an N-terminal extracellular domain containing two Ig-like C2-type (immunoglobulin-like) domains, followed by a single-pass transmembrane segment and a cytoplasmic C-terminal tail. CD19 expression is restricted to members of the B cell lineage. It functions as a co-receptor for B-cell antigen receptor (BCR), regulating signal transduction." [PMID:15778510]
comment: Category=gene. Requested by=CL.
synonym: "CD19" EXACT PRO-short-label [PRO:DNx]
synonym: "differentiation antigen CD19" EXACT []
synonym: "T-cell surface antigen Leu-12" EXACT []
synonym: "B-lymphocyte surface antigen B4" EXACT []
xref: IUPHARobj:2764
xref: PIRSF:PIRSF016630
is_a: PR:000000001 ! protein